Research | Baycrest

Chow, Tiffany Dr.

Tiffany Chow

Dr. Tiffany Chow, MD, MSc

Senior Scientist Rotman Research Institute, Behavioural Neurology, Dept of Medicine, Baycrest

Assistant Professor of Neurology Department of Medicine, Neurology Division, University of Toronto

Assistant Professor of Psychiatry Department of Medicine, Geriatric Psychiatry Division, University of Toronto

Research Focus

My clinical research is dedicated to finding meaningful interventions for patients with behavioural disturbances due to dementia. These interventions range from pharmacologic ways of compensating for neurotransmitter imbalances caused by the dementia to non-pharmacologic means, such as specialized Day Programs or dance. Against a backdrop of No Known Cure, clinical research in dementia is a deep frontier for neuroscientists. The most Frequently Asked Question in my Frontotemporal Dementia Clinic is, “Dr., how long will this dementia go on? What do we expect to happen over time?” My research goals have arisen from my best response thus far, that there are four phases to this behaviourally-disturbed type of dementia, beginning with a questionably symptomatic phase, a definitely abnormal behavioural and personality change that intensifies and almost always requires pharmacotherapy, then a third stage, during which the patients symptoms subside and become withdrawn, amotivated, and intermittently agitated. The fourth stage for this dementia resembles the final stages of all neurodegenerative dementias.

My research is an attempt to identify what causes that crucial shift from stage 2 to stage 3. Thus far, I cannot link that shift to a critical degree of structural atrophy.

My efforts have utilized in vivo radioligand PET imaging and functional MRI methods, as opposed to post-mortem tissue staining that is difficult to connect to the shift in behavioural disturbances we observe over the course of the illness. The long-range goal is to identify a clear target to inform pharmacotherapy.

Currently, I am most intrigued by an apparent subclinical response of cerebral cortex in FTD to memantine, which is hypothesized to have neuroprotective properties. The placebo-controlled crossover study to follow-up on results from the initial open-label FDG-PET study will launch later this year.

The nature of behavioural disturbances in dementia belies brain-behaviour correlations taught from lesion studies: by the time patients are diagnosed, the ravages of FTD and Alzheimer's disease have struck in several places, not just within one frontosubcortical circuit. Patients paradoxically manifest both apathy and hyperactive disinhibition during the first half of the illness.

As one of the investigators in the multidisciplinary Frontotemporal Dementia Workgroup, I am dedicated to advancing innovative and meaningful research in FTD by optimizing collaboration among investigators, facilitating patient and family participation in research, and providing a collegial, educational forum for investigators, clinicians and their trainees.

Publications

Title Source (Journal/Book/Conference) Authors/Presenters Published On Type
A case of semantic variant primary progressive aphasia with severe insular atrophy Neurocase Chow TW, Links KA, Masterman DL, Mendez MF, Vinters HV 1366862400 Journal Article
Neuroimaging during a Working Memory Task in Remote Traumatic Brain Injury: Evidence from NHL Alumni Esopenko C, Kumar PK, Alain C, Chow TW, McIntosh AR, Strother S, Levine B 1365825600 Presentation
Determinants of survival in autopsy-confirmed patients with behavioral variant frontotemporal dementia (bvFTD) Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Xie S, van Swieten JC, Seelaar H, Dopper EGP, Onyike CU, Hillis A, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin K, Johnson JK, Gorno-Tempini ML, Rosen H, Neuhaus J, Latham C, Lee AS, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor M, Warren JD, Fox NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow T, Manes F, Grafman J, Cappa SF, Freedman M, Miller BL, Grossman M 1365652800 Abstract
The Interaction between Traumatic Brain Injury and Aging: Evidence from NHL Alumni Esopenko C, Kumar PK, Alain C, Chow TW, McIntosh AR, Strother S, Levine B 1360126800 Presentation
Does Logopenic Progressive Aphasia Exist? Telehealth Geriatric Psychiatry Rounds Chow TW, Jokel R 1358485200 Presentation
P-Words That Go Together: PNFA, PT and slP City-wide Behavioural Neurology Videoconference Rounds Chow TW, Argent S, Jokel R 1357707600 Presentation
Incorporating new diagnostic schemas, genetics, and proteinopathy into the evaluation of frontotemporal degeneration. Continuum (Minneapolis, Minn.) Chow TW, Alobaidy AA 1357016400 Journal Article
Whole-brain white matter disruption in semantic and nonfluent variants of primary progressive aphasia. Human brain mapping Schwindt GC, Graham NL, Rochon E, Tang-Wai DF, Lobaugh NJ, Chow TW, Black SE 1357016400 Journal Article
The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: The next therapeutic frontier). Alzheimer's & dementia : the journal of the Alzheimer's Association Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Jackson G, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian ZS, Sutherland M, Abushakra S, Lewcock J, Farese R, Kenet RO, Laferla F, Perrin S, Whitaker S, Honig L, Mesulam MM, Boeve B, Grossman M, Miller BL, Cummings JL 1357016400 Journal Article
Frontotemporal degeneration, the next therapeutic frontier: Molecules and animal models for frontotemporal degeneration drug development. Alzheimer's & dementia : the journal of the Alzheimer's Association Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian Z, Sutherland M, Farese R, Miller BL, Cummings J 1357016400 Journal Article
Fluorodeoxyglucose positron emission tomography in semantic dementia after 6 months of memantine: an open-label pilot study. International journal of geriatric psychiatry Chow TW, Fam D, Graff-Guerrero A, Verhoeff NP, Tang-Wai DF, Masellis M, Black SE, Wilson AA, Houle S, Pollock BG 1357016400 Journal Article
When dementia is in the house: needs assessment survey for young caregivers. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques Nichols KR, Fam D, Cook C, Pearce M, Elliot G, Baago S, Rockwood K, Chow TW 1357016400 Journal Article
Changes to saccade behaviors in Parkinson's disease following dancing and observation of dancing. Frontiers in neurology Cameron IG, Brien DC, Links K, Robichaud S, Ryan JD, Munoz DP, Chow TW 1357016400 Journal Article
ACADEMIC GRAND ROUNDS: Dementia FAQs Penticton Regional Hospital Department of Psychiatry Chow TW 1354770000 Presentation
You can manage a dementia without cure: Frontotemporal degeneration Journal of Current Clinical Care Chow TW 1352955600 Journal Article
What Can You Do about Dementia? As a Caregiver and As a Vulnerable Aging Person Hadassah-WIZO group (Machar) Chow TW 1352696400 Presentation
Development of supportive services through community engagement in FTD International Journal of Psychiatry Shnall A, Agate A, Grinberg A, Huijbregts M, Nguyen M, Chow TW 1350273600 Journal Article
FDG-PET in semantic dementia after 6 months of memantine: an open-label study International Journal of Geriatric Psychiatry Chow TW, Fam D, Graff-Guerrero A, Verhoeff NPG, Binns MA, Tang-Wai DF, Masellis M, Black SE, Wilson AA, Houle S, Pollock BG 1349496000 Journal Article
When Dementia is in the House Alzheimer Society of Guelph and Wellington Chow TW 1349323200 Presentation
Abnormal network connectivity in frontotemporal dementia: Evidence for prefrontal isolation Cortex Farb NA, Grady CL, Strother S, Tang-Wai DF, Masellis M, Black S, Freedman M, Pollock BG, Campbell KL, Hasher L, Chow TW 1348459200 Journal Article
A case of apathy due to frontotemporal dementia responsive to memantine Neurocase Links KA, Black SE, Chow TW 1334462400 Journal Article
Neuroimaging in MCI: What to Order in What Order Rotman Research Institute Annual Conference Chow TW 1332734400 Presentation
Revisiting Memory in Alzheimer's Disease American Neuropsychiatric Association Gilboa A, Anderson N, Chow TW 1332475200 Presentation
Serotonergic function and treatment of behavioral and psychological symptoms of frontotemporal dementia. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry Herrmann N, Black SE, Chow T, Cappell J, Tang-Wai DF, Lanctôt KL 1325394000 Journal Article
Cholinergic pathways and cognition in patients with schizophrenia: a pilot study. Schizophrenia research Rajji TK, Chow TW, Voineskos AN, Links KA, Miranda D, Mamo DC, Ismail Z, Pollock BG, Mulsant BH 1325394000 Journal Article
Trajectories of behavioral disturbance in dementia. Journal of Alzheimer's disease : JAD Chow TW, Fridhandler JD, Binns MA, Lee A, Merrilees J, Rosen HJ, Ketelle R, Miller BL 1325394000 Journal Article
An [11C]SB-13 PET study correlating neuropsychiatric symptoms in Alzheimer’s disease with regional beta-amyloid burden Psychiatry Research: Neuroimaging Kaye ED, Honjo K, Petrovic-Poljak A, Reekum R, Streiner DL, Wilson AA, Black SE, Freedman M, Rusjan P, Houle S, Chow TW, Verhoeff NPLG 1325307600 Journal Article
Perils and PIBfalls of Imaging Patients with Alzheimer's Disease Centre for Addiction and Mental Health PET Research Seminar Chow TW 1322802000 Presentation
Does Logopenic Progressive Aphasia Exist? City-wide Behavioural Neurology Videoconference Rounds Chow TW, Jokel R 1322024400 Presentation
Frontotemporal Dementia Chinese Dementia Research Association's 5th Congress of Asian Society against Dementia Chow TW 1320555600 Presentation
Hong Kong University Alzheimer's Disease Research Network Seminar Dementia FAQs HKU Alzheimer's Disease Research Network and Research Centre of Heart, Brain, Hormone & Healthy Aging, Department of Psychiatry Division of Geriatrics, Department of Medicine, QMH, Department of Anat. Chow TW 1320379200 Presentation
Differentiating normal from pathological atrophy: When Is Frontotemporal Atrophy Normal? Amyotrophic Lateral Sclerosis and Frontotemporal Dementias Chow TW 1320120000 Book Chapter
Workshop: Dementia FAQs Canadian Conference on Dementia Chow TW 1319774400 Presentation
When Is Frontotemporal Atrophy Normal? Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias Chow TW 1317960000 Book Chapter
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia Brain Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Neuhaus J, van Swieten JC, Seelaar H, Dopper EGP, Onyike CU, Hillis AE, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin KP, Johnson JK, Gorno-Tempini ML, Rosen H, Latham C, Lee A, Kipps CM, Lillo P, Piguet O, Rohrer J, Rossor M, Warren NC, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Grossman M, and Miller BL 1317873600 Journal Article
An Open-Label Study of the Short-Term Effects of Memantine on FDG-PET in Frontotemporal Dementia Neuropsychiatric Disease and Treatment Chow TW, Graff-Guerrero A, Verhoeff NPG, Binns MA, Tang-Wai DF, Freedman M, Masellis M, Black SE, Wilson AA, Houle S, Pollock BG 1310184000 Journal Article
Serotonergic function and treatment of behavioural and psychological symptoms of frontotemporal dementia American Journal of Geriatric Psychiatry Herrmann N, Black SE, Chow TW, Cappell J, Tang-Wai DF, Lanctot KL 1310184000 Journal Article
Implication of the salience network in frontotemporal dementia Canadian Neurological Sciences Federation meeting Chow TW 1308110400 Presentation
Annual Dementia Teaching Course:An Update on Frontotemporal Dementia Implication of the Salience Network in Frontotemporal Dementia Canadian Neurological Sciences Federation meeting Chow TW 1308110400 Presentation
Brain perfusion and NPI correlates of apathy in Alzheimer’s and frontotemporal dementia Neurology Chow TW, Binns MA, Lam IWS, Szilagyi G, Links KA, Black SE 1306900800 Journal Article
Visual rating versus volumetry to detect frontotemporal dementia Dementia and Geriatric Cognitive Disorders Chow TW, Gao F, Links KA, Ween JE, Tang-Wai DF, Ramirez J, Scott CJM, Freedman M, Stuss DT, Black SE 1306814400 Journal Article
Which Neuroimaging Biomarkers are Ready for Primetime? American Geriatrics Society Chow TW, Nair A, Auchus A 1305345600 Presentation
Comparative utility of linear, area and volumetric measures in detecting brain changes in FTD in correlation with cognitive performance 5th International Conference on Frontotemporal Dementia Gao FQ, Deshpande N, Ramierez J, Van Gaal S, Chow TW, Freedman M, Behl P, Black SE 1305259200 Presentation
An international needs assessment of caregivers for frontotemporal dementia syndromes Canadian Journal of Neurological Sciences Chow TW, Pio FJ, Rockwood K 1304740800 Journal Article
A case of frontotemporal dementia with severe insular atrophy Neurocase Chow TW, Links KA, Masterman DL, Mendez MF, Vinters HV 1304740800 Journal Article
Prolactin response to Citalopram challenge predicts behavioural improvement in Frontotemporal Dementia INTERNATIONAL PSYCHOGERIATRICS Herrmann N, Black SE, Chow TW, Freedman M, Lanctôt KL 1303963200 Abstract
Neuroplasticity in dementia following language intervention: Illusion or possibility? Alzheimer's & Dementia Jokel R, Anderson N, Black S, Rochon E, Freedman M, Chow T, Tang-Wai D 1303617600 Journal Article
Moderate to advanced stages of dementia: Palliative care questions and some answers American Academy of Neurology Annual Meeting Chow TW 1303272000 Presentation
Sensitivity of Diagnostic Criteria in Autopsy-Confirmed Patients with Behavioral Variant Frontotemporal Dementia (bvFTD): First Report of the International bvFTD Criteria Consortium NEUROLOGY Rascovsky K, Hodges JR, Knopman D, Mendez MF, Kramer JH, Van Swieten JC, Seelaar H, Dopper EGP, Onyike CU, Hillis A, Josephs KA, Boeve BF, Kertesz A, Seeley WW, Rankin K, Johnson JK, Tempini MLG, Rosen H, Neuhaus J, Latham C, Lee AS, Kipps CM, Lillo P, Piguet O, Rohrer JD, Rossor M, Galasko D, Salmon DP, Black SE, Mesulam M, Weintraub S, Dickerson BC, Diehl-Schmid J, Pasquier F, Deramecourt V, Lebert F, Pijnenburg Y, Chow TW, Manes F, Grafman J, Cappa SF, Freedman M, Warren JD, Fox NC, Grossman M, Miller BL 1302667200 Abstract
The Impact of the Right Insula on Behavior and Cognition in Frontotemporal Dementia Neurology Farb N, Chow TW, Tang-Wai D, Masellis M 1302580800 Presentation
Sensitivity of Diagnostic Criteria in Autopsy-Confirmed Patients with Behavioral Variant Frontotemporal Dementia (bvFTD): First Report of the International bvFTD Criteria Consortium Neurology American Academy of Neurology Rascovsky K, Hodges J, Knopman D, Chow TW, Manes F, Grafman J, Cappa S, Freedman M, Warren J, Fox N, Grossman M, Miller B 1302580800 Abstract
The Impact of the Right Insula on Behavior and Cognition in Frontotemporal Dementia Neurology American Academy of Neurology Farb N, Chow TW, Tang-Wai D, Masellis M 1302580800 Abstract
Course 2ES.003: Advanced Palliative Care and Symptom management of ALS, Alzheimer's Disease, Parkinson's Disease, and Brain Tumors Moderate to Advanced Stages of Dementia: Palliative Care Questions and Some Answers American Academy of Neurology Annual Meeting Chow TW 1302408000 Presentation
Frontotemporal dementia: The next therapeutic frontier Lou Ruvo Brain Institute Chow TW 1301025600 Presentation
Frontotemporal Dementia: The Next Therapeutic Frontier Lou Ruvo Brain Institute Chow TW 1301025600 Presentation
Treatment of Behavioural and Psychological Symptoms of Dementia in Frontotemporal Dementia with Citalopram AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Herrmann N, Chow TW, Black SE, Freedman M, Lanctot KL 1300680000 Abstract
Effects of aging on 5-HT2AR binding: a HRRT PET study with and without partial volume corrections International Journal of Geriatric Psychiatry Uchida H, Chow TW, Graff-Guerrero A, Kapur S, Houle S, Smith GS, Pollock BG, Mulsant BH, Mamo DC 1299733200 Journal Article
Speaker's Panel on Bill 52 Donna Cansfield, Ontario MPP Chow TW 1299733200 Presentation
Visual rating vs. volumetry to detect frontotemporal dementia. Dementia and Geriatric Cognitive Disorders Chow TW, Gao F, Links KA, Ween JE, Tang-Wai DF, Ramirez J, Scott CJM, Freedman M, Stuss DT, Black SE 1298955600 Journal Article
Oh, the Things You'll See with FTD Rotman Research Institute Weekly Rounds Chow TW 1298869200 Presentation
What Can We Learn about the Lifespan from Studying Dementia? Institute for Life Course and Aging Chow TW 1294894800 Presentation
What Can We Learn about the Lifespan from Studying Dementia? Institute for Life Course and Aging Chow TW 1294894800 Presentation
Effects of aging on 5-HT(2A) R binding: a HRRT PET study with and without partial volume corrections. International Journal of Geriatric Psychiatry Uchida H, Chow TW, Mamo DC, Kapur S, Mulsant BH, Houle S, Pollock BG, Graff-Guerrero A 1293858000 Journal Article
What is Frontotemporal Dementia and How Can We Manage It? McGill University Psychiatry and Neurology Rounds Chow TW 1292475600 Presentation
Clinicopathological Case: Rapidly Progressive Frontotemporal Dementia That on Autopsy, Wasn’t City-wide Behavioural Neurology International Video-teleconference Rounds Chow TW, Hazrati L 1291179600 Presentation
Can Memantine Bring Salience to the Salience Network? Robarts Research Institute Chow TW 1288756800 Presentation
Gaze palsy, alien limb, and chorea: Movement disorders in dementia Canadian Consortium on Dementia Chow TW 1287374400 Presentation
What are the different initial presentations of frontotemporal dementia? Indiana Alzheimer Disease Center Chow TW 1286337600 Presentation
From prevention to palliation Canadian Association of Geriatric Psychiatry Chow TW 1285128000 Presentation
Prevalence of primitive reflexes and parkinsonian signs in dementia Canadian Journal of Neurological Sciences Links KA, Merims D, Binns MA, Freedman M, Chow TW 1283313600 Journal Article
Occupation attributes relate to location of atrophy in frontotemporal lobar degeneration Neuropsychologia Spreng RN, Rosen H, Strother S, Chow TW, Diehl-Schmid J, Freedman M, Graff-Radford N, Hodges J, Lipton A, Mendez M, Morelli S, Black SE, Miller BL, Levine B 1283140800 Journal Article
Meet the Scientist Rotman Research Institute/KLARU Summer Rounds Chow TW 1281326400 Presentation
The effect of memantine on FDG-PET imaging in frontotemporal dementia Alzheimer’s Association International Conference on Alzheimer’s Disease Chow TW, Graff-Guerrero A, Freedman M, Tang-Wai D, Black SE, Pollock BG 1278734400 Presentation
A brief history of research in frontotemporal dementia (and celebration of Bruce Miller's impact on it) Frontiers in Human Neuroscience Chow TW 1277438400 Abstract
What is Frontotemporal Dementia and How Can We Manage It? Alzheimer Society of Sarnia Annual General Meeting Chow TW 1276142400 Presentation
What to pack for your aging journey International Association for Jewish Homes and Services for the Aging Symposium Chow TW 1273982400 Presentation
Dementia: From Beginning to End University of Toronto Division of Neurology Chow TW 1272081600 Presentation
Has study of patients with dementia shed any light on brain-behavior relationships? American Academy of Neurology Annual Meeting Chow TW 1270958400 Presentation
A brief history of research in frontotemporal dementia (and celebration of Bruce Miller's impact on it) 20th Anniversary of the Rotman Research Institute Chow TW 1269489600 Presentation
Concepts in Caring for Frontotemporal Dementia Dalhousie University Chow TW 1268110800 Presentation
Recollection and familiarity for public events in neurologically intact older adults and two brain-damaged patients Neuropsychologia Petrican R, Gopie N, Leach L, Chow TW, Richards B, Moscovitch M 1267419600 Journal Article
Pre- and Post-Memantine FDG-PET Imaging in Frontotemporal Dementia NEUROLOGY Chow TW, Graff-Guerrero A, Freedman M, Tang-Wai D, Black SE, Pollock BG 1267419600 Abstract
From Breakthroughs in Frontotemporal Dementia to Bedside Clinical Neuroscience Rounds for the Divisions of Neurology and Neurosurgery Chow TW 1267419600 Presentation
Alzheimer's disease neuropathologic changes in semantic dementia Neurocase Chow TW, Varpetian A, Moss T, Vinters HV, Marquez S, Miller C 1267333200 Journal Article
Women and Alzheimer’s Disease: In the Past and for the Future Baycrest Speakers Series Znaimer L, Chow TW 1265778000 Presentation
What's on the Differential Diagnosis List for Frontotemporal Dementia? Rotman Research Institute Weekly Rounds) Chow TW 1263186000 Presentation
The brainstem: anatomy, assessment, and clinical syndromes. Journal of Neuropsychiatry and Clinical Neurosciences Hurley RA, Flashman LA, Chow TW, Taber KH 1262322000 Journal Article
Managing the Caregiver and the Patient with Frontotemporal Dementia BC Mental Health Chow TW 1258693200 Presentation
Is It or Ain’t It FTD? BC Mental Health Chow TW 1258693200 Presentation
What’s on the differential diagnosis list for frontotemporal dementia? City-wide Behavioural Neurology International Video-teleconference Rounds Chow TW 1257915600 Presentation
Prevalence of primitive reflexes and Parkinsonism among patients with dementia Canadian Conference on Dementia Links K, Merims D, Binns M, Freedman M, Chow TW 1254456000 Presentation
Clinical impact of latest genetics and neuropath news in FTD 5th Canadian Conference on Dementia Chow TW 1254456000 Presentation
Pre-and post-memantine FDG-PET imaging in frontotemporal dementia 5th Canadian Conference on Dementia Chow TW, Binns MA, Freedman M, Pollock BG, Verhoeff NP, Graff-Guerrero A 1254369600 Presentation
Pre- and post-memantine FDG-PET imaging in frontotemporal dementia 5th Canadian Conference on Dementia Chow TW, Binns MA, Freedman M, Pollock B, Verhoeff NPLG, Graff-Guerrero A 1254369600 Presentation
A million tweets to remember Chow TW 1254369600 Presentation
Apathy is not associated with basal ganglia atrophy in frontotemporal dementia American Journal of Geriatric Psychiatry Links KA, Chow TW, Binns M, Freedman M, Stuss DT, Scott CJ, Ramirez J, Black SE 1251777600 Journal Article
The Road to Fearless Caregiving Northwestern University Chow TW 1249099200 Presentation
Apathy symptom profile and behavioral associations in frontotemporal dementia vs dementia of Alzheimer type Archives of Neurology Chow TW, Binns MA, Cummings JL, Lam I, Black SE, Miller BL, Freedman M, Stuss DT, van Reekum R 1248148800 Journal Article
Test-retest variability of high resolution positron emission tomography (PET) imaging of cortical serotonin (5HT2A) receptors in older, healthy adults BMC Medical Imaging Chow TW, Mamo DC, Uchida H, Houle S, Smith G, Pollock BG, Mulsant BH 1246852800 Journal Article
Prevalence of Primitive Reflexes and Parkinsonism Among Patients with Dementia UNIVERSITY OF TORONTO DEPARTMENT OF PSYCHIATRY Links K, Merims D, Binns M, Freedman M, Chow TW 1246161600 Abstract
High resolution research tomography with healthy elderly does not require partial volume correction 35th Annual Harvey Stancer Research Day Chow T, Graff-Guerrero A, Uchida H, Mamo DC, Houle S, Kapur S, Pollock BG, Mulsant BH 1245902400 Presentation
When Is Frontotemporal Atrophy Normal? Research Workshop on Frontotemporal Dementia in ALS Chow TW 1243828800 Presentation
Apathy symptom profile and behavioral associations in frontotemporal dementia vs. Alzheimer’s disease Psychiatry Grand Rounds Binns MA, Chow TW 1242964800 Presentation
Apathy in dementia is a significant behavioural challenge Canadian Geriatric Scoeity Chow TW 1239768000 Presentation
Managing difficult behaviours due to frontotemporal dementia Rewilak D, Chow T 1239681600 Presentation
Pre- and post-memantine FDG-PET imaging in frontotemporal dementia AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Chow T, Binns M, Dombrower H, Freedman M, Verhoeff P, Pollock BG 1236229200 Abstract
Pre- and post-memantine FDG-PET imaging in frontotemporal dementia. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Chow TW, Binns MA, Freedman M, Pollock B, Verhoeff NPLG, Graff-Guerrero A 1236229200 Abstract
Treatment of behavioral and psychological symptoms of dementia in Frontotemporal Dementia with Citalopram AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Herrmann N, Black SE, Chow TW, Freedman M, Lanctot KL 1236229200 Abstract
Does your brainstem look from the outside? American Neuropsychiatric Association Annual Meeting Chow TW 1233464400 Presentation
100 Years After Alzheimer: Contemporary Neurology Practice Assessment of Referrals for Dementia American Journal Of Alzheimer's Disease And Other Dementias Chow TW, Binder C, Smyth S, Cohen S, Robillard A 1230786000 Journal Article
The Rising Tide of Alzheimers Canadian Broadcasting Company Chow TW 1230786000 Presentation
How to get around apathy over the Neuropsychiatric Inventory Rotman Rounds Binns MA, Chow TW 1226293200 Presentation
Review: insufficient evidence on Huperzine A for Alzheimer's. Evidence-Based Mental Health Chow TW 1225512000 Journal Article
How Can We Best Support FTD Caregivers? Alzheimer Society of Hamilton and Halton Chow TW 1224561600 Presentation
Overlap in frontotemporal atrophy between normal aging and patients with frontotemporal dementias Alzheimer Disease & Associated Disorders Chow TW, Binns MA, Freedman M, Stuss DT, Ramirez J, Scott CJM, Black SE 1222833600 Journal Article
Apathy is associated with harmful behaviors in frontotemporal dementia and Alzheimer’s disease Dementia and Geriatric Cognitive Disorders Chow TW, Binns MA, van Reekum R, Freedman M, Cummings JL, Lam I, Black SE, Miller BL 1220414400 Abstract
Occupation attributes relate to laterality of atrophy in frontotemporal lobar degeneration Dementia and Geriatric Cognitive Disorders Spreng RN, Rosen HJ, Black SE, Chow TW, Diehl-Schmid J, Freedman M, Graff-Radford NR, Hodges JR, Lipton AM, Mendez MF, Morelli SA, Miller BL, Levine B 1220414400 Abstract
Magnetic resonance imaging in frontotemporal dementia shows subcortical atrophy Dementia and Geriatric Cognitive Disorders Chow TW, Izenberg A, Binns MA, Freedman M, Stuss DT, Scott CJM, Ramirez J, Black SE 1215662400 Journal Article
Reliable measurement of cortical 5HT2 receptors in older adults with [18F]-setoperone PET imaging shows gender and aging effects Harvey Stancer Research Day Chow T, Uchida H, Graff-Guerrero A, Mamo D, Houle S, Smith G, Pollock BG, Mulsant BH 1213848000 Presentation
Frontotemporal dementia: Translating research into clinical practice Dementia Course Chow TW 1213675200 Presentation
Distraction during relational reasoning: The role of prefrontal cortex in interference control Neuropsychologia Krawczyk DC, Morrison RG, Viskontas I, Holyoak KJ, Chow TW, Mendez MF, Miller BL, Knowlton BJ 1212292800 Journal Article
Dancing with Parkinson's CBC News Sunday Chow TW 1211947200 Presentation
Managing the Frontotemporal Dementias McMaster University Geriatric Medicine Grand Rounds Chow TW 1210305600 Presentation
Neuroimaging Advances and New Ethical Dilemmas in Alzheimer’s Disease Detection The Rutherford Show Chow TW 1206590400 Presentation
PET Imaging in Dementia 18th Annual Rotman Research Institute Conference Chow TW 1206504000 Presentation
Diagnosis and treatment of dementia: 2. Diagnosis Canadian Medical Association Journal Feldman HH, Jacova C, Robillard A, Garcia A, Chow T, Borrie M, Schipper HM, Blair M, Kertesz A, Chertkow H 1206417600 Journal Article
Test-Retest Variability of High Resolution Positron Emission Tomography (PET) Imaging of Cortical Serotonin (5HT2A) Receptors in Older, Healthy Adults 18th Annual Rotman Research Institute Conference Chow TW 1206417600 Presentation
Reliability of evaluation of cortical 5HT2 receptors in older adults with [18F]-setoperone PET imaging BRAIN AND COGNITION Uchida H, Chow TW, Mamo DC, Houle S, Smith G, Pollock BG, Mulsant BH 1206331200 Abstract
Multidisciplinary design and implementation of a day program specialized for the frontotemporal dementias American Journal of Alzheimer's Disease and Other Dementias Grinberg A, Lagunoff J, Phillips D, Stern B, Goodman M, Chow T 1199163600 Journal Article
Managing t he Frontotemporal Dementias Geriatric Medicine Ground Rounds Chow T 1199163600 Presentation
Frontotemporal Dementia: Translating Research into Current Clinical Practice. Congress of the Canadian Neurological Sciences Federation Dementia Course Chow T 1199163600 Presentation
"Speaking of which: How to distinguish between primary progressive aphasias in the clinic" Canadian Consortium on Dementia Chow TW 1192680000 Presentation
Managing the Frontotemporal Dementias Canadian Consortium on Dementia Chow TW 1192680000 Presentation
Structural neuroimaging in the diagnosis of dementia Alzheimer's & Dementia Chow TW 1191211200 Journal Article
Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): Current limitations and future directions Alzheimer Disease and Associated Disorders Rascovsky K, Hodges JR, Kipps CM, Johnson JK, Seeley WW, Mendez MF, Knopman D, Kertesz A, Mesulam M, Salmon DP, Galasko D, Chow TW, DeCarli C, Hillis A, Josephs K, Kramer JH, Weintraub S, Grossman M, Gorno-Tempini ML, Miller BM 1191211200 Journal Article
Studying patients with dementia using PET imaging PET Research Seminar Chow TW 1189656000 Presentation
Early detection of the frontotemporal dementias 2nd International Research Workshop on Frontotemporal Dementia in ALS Chow TW 1181448000 Presentation
SSRIs for treatment of cognition in AD and potential disease modification Neuropsychiatric Disease and Treatment Chow TW, Pollock BG, Milgram NW, 1178510400 Journal Article
Focal Cortical Syndromes American Academy of Neurology Chow T 1178337600 Presentation
Apathy and other behaviors in frontotemporal dementia Annual meeting of the American Academy of Neurology Binns MA, Chow TW 1178164800 Presentation
From clinic to genetics lab and back again: The impact of genetic breakthroughs Many Faces of Dementia Conference Chow TW 1172206800 Presentation
How does Alzheimer’s research influence the other dementias? Artiss Powell Memorial Lecture Chow TW 1170219600 Presentation
Comparison of manual and semi-automated delineation of regions of interest for radioligand PET imaging analysis BMC Nuclear Medicine Chow TW, Takeshita S, Honjo K, Pataky CE, St Jacques PL, Kusano ML, Caldwell CB, Ramirez J, Black S, Verhoeff NPLG 1167627600 Journal Article
How does Alzheimers research influence the other dementias? Artiss Powell Memorial Lecture Chow T 1167627600 Presentation
Apathy and other behaviours in frontotemporal dementia Annual meeting of the American Academy of Neurology Chow T 1167627600 Presentation
Potential cognitive enhancing and disease modification effects of SSRIs for Alzheimer's disease. Neuropsychiatric Disease and Treatment Chow TW, Pollock BG, Milgram NW 1167627600 Journal Article
Frontal-subcortical circuits and a rationale for neuroreceptor quanitification in frontotemporal dementia Treatment of Frontotemporal Dementia: Identifying Pathophysiologic Targets Chow TW 1165381200 Presentation
Frontal-subcortical circuits and a rationale for neuroreceptor quantification in FTD NEUROPSYCHOPHARMACOLOGY Chow T, Rusjan P, Meyer J, Verhoeff NP, Pollock BG, Smith G 1165122000 Abstract
Treatment of frontotemporal dementia: Identifying pathophysiologic targets 45th Annual meeting of the American College of Neuropsychopharmacology Chow TW, Clark L, Josephs K, Zetterberg H, Pollock BG 1165122000 Presentation
Apathy, depression, incipient dementia? A difficult differential diagnosis. CAMH-KLARU Conference Chow T, Mamo D 1161316800 Presentation
Diagnosis of Frontotemporal Dementia UCSF International Conference on Frontotemporal Dementia Chow TW 1157515200 Presentation
Iatrogenic apathy in frontotemporal dementia University of California at San Francisco Chow TW, Binns MA, Pataky CE, Huang D, Yeo T, Cummings JL, Lam I, Black SE, Kelly S, Miller BL, Freedman M 1157515200 Presentation
Left orbitofrontal atrophy correlates with disinhibition and apathy in frontotemporal degeneration ALZHEIMER’S & DEMENTIA Chow TW, Binns MA, Freedman M, Stuss DT, Ramirez J, Verhoeff NPLG, Black SE 1153022400 Abstract
Exploring the recognition memory deficit in Parkinson's disease: estimates of recollection versus familiarity Brain Davidson PSR, Anaki D, Saint-Cyr J, Chow TW, Moscovitch M 1151726400 Journal Article
The diagnostic utility of regional atrophy in frontotemporal degeneration ALZHEIMER’S & DEMENTIA Chow TW, Binns MA, Freedman M, Stuss DT, Ramirez J, Black SE 1150344000 Abstract
The neurology of frontotemporal degeneration Department of Communication Disorders Conference Chow TW 1147406400 Presentation
Frontal-subcortical circuits The Human Frontal Lobes: Functions and Disorders Chow TW, Cummings JL 1146974400 Book Chapter
Early stages of FTD show subcortical atrophy NEUROLOGY Izenberg AE, Chow TW, Binns MA, Freedman M, Stuss DT, Ramirez J, Black SE 1144209600 Abstract
From clinic to genetics lab and back again: Do genetics breakthroughs impact AD management? Rotman Rounds Chow TW 1143950400 Presentation
Early stages of FTD show subcortical atrophy 58th Annual Meeting of the American-Academy-of-Neurology Izenberg AE, Chow T, Binns M, Freedman M, Stuss D, Ramirez J, Black S 1142312400 Presentation
Alexithymia in dementia University of California at San Francisco Pataky CE, St Jacques P, Davidson P, Grady C, Chow TW 1141794000 Presentation
Early onset dementias Alzheimer's Society of Toronto Chow TW 1137128400 Presentation
Variations in regional SPECT hypoperfusion and clinical features in frontotemporal dementia Neurology McMurtray AM, Chen A, Shapira JS, Chow TW, Mishkin F, Miller BL, Mendez MF 1136091600 Journal Article
Asian Americans and Alzheimer's Disease: Assimilation, Culture, and Beliefs. Journal of Aging Studies Jones RS, Chow TW, Gatz M 1136091600 Journal Article
MMSE scores decline at a greater rate in frontotemporal degeneration than in AD Dementia and Geriatric Cognitive Disorders Chow TW, Hynan LS, Lipton AM 1136091600 Journal Article
Frontal-subcortical circuits adn a rationale for neuroceptor quantification in frontotemporal dementia Annual meeting of the American College of Neuropsychopharmacology: Treatment of Frontotemporal Dementia - Identifying Pathophysiologic Targets Chow T 1136091600 Presentation
Treatment of frontotemporal dementia: Identifying pathophysiologic targets" American College of Neuropsychopharmacology Chow T 1136091600 Presentation
Recognition memory for emotional stimuli in frontotemporal dementia 12th Annual Meeting of the Cognitive Neuroscience Society St Jacques PL, Chow TW, Grady CL, Davidson PSR, Pataky CE, Springer M 1133413200 Presentation
What to do about Early Onset Dementias 2nd Annual Dementia Care Providers Network Chow TW 1131426000 Presentation
Evidence for a Serotonergic Deficit in Frontotemporal Degeneration International Psychiatric Association Congress Chow TW 1127448000 Presentation
Evidence Based management of Frontotemporal Dementias: Is There Any? Geriatric Research Education and Clinical Center Noon Educational Series Chow TW 1122350400 Presentation
Evaluation and refinement of an MR-based brain pet partial volume correction method using the Zubal brain phantom JOURNAL OF NUCLEAR MEDICINE Kusano ML, Caldwell CB, Lanctot KL, Chow TW 1119067200 Abstract
Frontotemporal lobar degeneration - Demographic characteristics of 353 patients Archives of Neurology Johnson JK, Diehl J, Mendez MF, Chow TW, Neuhaus J, Pace-Savitsky C, Shapiro JS, Rosen HJ, Forstl H, Kurz A, Miller BL 1117598400 Journal Article
A dementia by any other name. What if it is not Alzheimer’s? Alzheimer’s Care Quarterly Chow TW 1115611200 Journal Article
Neuropsychiatry in frontotemporal degeneration correlates with right dorsolateral prefrontal and left temporal atrophy Sixteenth Annual Meeting of the American Neuropsychiatric Association Chow TW, Binns MA, Ramirez J, Black SE 1108270800 Presentation
Treatment approaches to symptoms associated with frontotemporal degeneration Current Psychiatry Reports Chow TW 1104555600 Journal Article
Functional analysis of a recurrent missense mutation in Notch3 in CADASIL Journal of Neurology, Neurosurgery & Psychiatry Haritunians T, Chow T, De Lange RPJ, Nichols JT, Ghavimi D, Dorrani N, St Clair DM, Weinmaster G, Schanen C 1104555600 Journal Article
Referral patterns for syndromes associated with frontotemporal lobar degeneration Alzheimer Disease and Associated Disorders Chow TW, Hodges J, Miller BL, Smith V, Mendez MF, Lipton AM, Dawson K 1104555600 Journal Article
Reduced serotonin 1a receptor binding potential and abnormal oral behaviors in frontotemporal degeneration Neurology Chow TW, Verhoeff NPLG, Takeshita S, Freedman M, Black S, Wilson A, Hussey D, Houle S, Meyer J 1104555600 Abstract
Overview of Frontotemporal Degeneration City-Wide Grand Rounds, University of Toronto, Division of Neurology Chow T 1104555600 Presentation
Overview of Frontotemporal Dementia University of Toronto Fifth Annual Behavioural Neurology Academic Clinic Day Program Chow T 1104555600 Presentation
Is There Any Evidence-Based Management of Frontotemporal Dementia? Baycrest Centre Psychiatry Grand Rounds Chow T 1104555600 Presentation
The differential diagnosis of pseudobulbar affect (PBA). Distinguishing PBA among disorders of mood and affect CNS spectrums Arciniegas DB, Lauterbach EC, Anderson KE, Chow TW, Flashman LA, Hurley RA, Kaufer DI, McAllister TW, Reeve A, Schiffer RB, Silver JM 1104555600 Journal Article
Update on Frontotemporal Dementia Medicine Grand Rounds Chow TW 1101186000 Presentation
Update on Frontotemporal Dementia Annual Meeting of the Minnesota Psychiatric Society Chow T 1099108800 Presentation
Spousal caregiving for frontotemporal dementia Kunin-Lunenfeld Applied Research Unit 4th Annual Conference McCleary L, Marziali E, Chow TW 1099022400 Presentation
Depression in frontotemporal dementia is associated with decreased left temporal lobe 5HT1a receptor density ANNALS OF NEUROLOGY Chow TW, Verhoeff NPLG, Takeshita S, St Jacques PL, Freedman M, Black SE, Wilson A, Hussey D, Houle S, Meyer J 1096862400 Abstract
Evidence-based management of frontotemporal degeneration with serotonergic agents INTERNATIONAL PSYCHOGERIATRICS Chow T 1094011200 Abstract
Cognitive decline, Gerstmann's syndrome, and apraxia in a case of corticobasal ganglionic degeneration (CBGD) International Journal Of Psychology Siegenthaler AL, Stokes KA, Park NW, Chow TW 1091937600 Abstract
Cognitive decline, Gerstmann syndrome, and apraxia in a case of Corticobasal Ganglionic Degeneration (CBGD) International Journal of Psychology Siegenthaler AL, Stokes KA, Park NW, Chow TW 1091937600 Presentation
A Dementia by Any Other Name Alzheimer's Association Chow TW 1090036800 Presentation
Supporting caregivers of patients with frontotemporal dementia Symposium for Frontotemporal Dementia McCleary L, Marziali E, Chow TW 1089691200 Presentation
Volumetric correlation of basal ganglia and physical disability in frontotemporal lobar degeneration Symposium for Frontotemporal Dementia Thomas VS, St Jacques PL, Chow TW 1089691200 Presentation
Reduced serotonin 1a receptors in depressed frontotemporal lobar degeneration subjects Symposium for Frontotemporal Dementia Chow TW, Verhoeff NPLG, Takeshita S, Freedman M, Black SE, Wilson A, Hussey D, Houle S, Meyer J 1089691200 Presentation
What's New in Dementia Medication and Research? A Look at Frontotemporal Dementia Alzheimer's Society of Toronto Chow TW 1086840000 Presentation
New Uses for Cholinesterase Inhibitors Clinical and Ethical Issues in Geriatric Care Chow TW 1082088000 Presentation
Ethnic Diversity in Dementia Annual Conference of the Connecticut Chapter of the Alzheimer's Association Chow TW 1080795600 Presentation
A neurocomputational model of analogical reasoning and its breakdown in frontotemporal lobar degeneration Journal of Cognitive Neuroscience Morrison RG, Krawczyk DC, Holyoak KJ, Hummel JE, Chow TW, Miller BL, Knowlton BJ 1072933200 Journal Article
Clinicopathological concordance of dementia diagnoses by community versus tertiary care clinicians American Journal of Alzheimer's Disease and Other Dementias Mok W, Chow TW, Zheng L, Mack WJ, Miller C 1072933200 Journal Article
Relational integration and executive function in Alzheimer's disease Neuropsychology Waltz JA, Knowlton BJ, Holyoak KJ, McPherson S, Boone KB, Back C, Reback E, O'Connor S, Masterman D, Chow T, Cummings JL, Miller BL 1072933200 Journal Article
Functional Imaging Studies: (Wo)Man vs. Machine in ROI Analysis Rotman Rounds Chow T 1072933200 Presentation
The Big Picture: When and Why to Order Neuroimaging St. Michael's Hospital Psychiatry Grand Rounds Chow T 1072933200 Presentation
Imaging Issues in Dementia Baycrest Hospital Department of Psychology Grand Rounds Chow T 1072933200 Presentation
A Case of Early Onset Dementia with Vertigo Baycrest Centre Bahavioral Neurology Rounds Chow T 1072933200 Presentation
Is There a Serotonergic Deficit in Frontotemporal Degeneration Annual University of Toronto Neurology Faculty Research Day Chow T 1072933200 Presentation
Rett Syndrome and Frontotemporal Dementia: Features Shared by the Dementias of the Very Young and Middle Aged Baycrest Centre Behavioral Neurology Rounds Chow T 1072933200 Presentation
New Use of Cholinesterase Inhibitors Lecture for Clinical and Ethical Issues in Geriatric Care, Baycrest Centre Chow T 1072933200 Presentation
Evaluating drug studies: When should a study cause me to change my practice? Alzheimer's Disease Research Center Dementia Update Conference Chow TW 1068872400 Presentation
Early Onset Dementias 'Health on the Line' with Avery Haines Chow TW 1065758400 Presentation
Caregiver reliability in reporting symptoms of dementia among Japanese-Americans in Hawaii 2nd Canadian Colloquium on Dementia Chow TW, Mok W, Vigen C, Masaki K 1064980800 Presentation
Asian and Pacific Islander Communities' Response to Guidelines for Alzheimer's Disease Care UCSF Memory and Aging Center Team Conference Chow TW 1054872000 Presentation
MMSE scores decline at a greater rate in frontotemporal lobar degeneration than in Alzheimer's disease NEUROLOGY Lipton A, Chow TW, Hynan L 1052798400 Abstract
Asian and Pacific Islander Communities' Response to Guidelines for Alzheimer's Disease Care Castle Medical Center Medicine Grand Rounds Chow TW 1049774400 Presentation
The role of prefrontal cortex in inhibiting competing perceptual and semantic information in relational reasoning JOURNAL OF COGNITIVE NEUROSCIENCE Krawczyk DC, Morrison RG, Holyoak KJ, Chow TW, Mendez M, Knowlton BJ 1049000400 Abstract
Successful coalition building between Grassroots Organizations and a mainstream/corporate organization Workshop for American Society on Aging/National Coalition on Aging meeting Chow TW 1047704400 Presentation
The Asian and Pacific Islander Communities’ Response to Guidelines for AD Care Faces of Dementia Conference Chow TW 1046408400 Presentation
The Big Picture: When & Why to Order Neuroimaging USC and Alzheimer's Association of LA, Riverside and San Bernadino Counties Faces of Dementia Conference Chow TW 1046408400 Presentation
Novel tau polymorphisms, tau haplotypes, and splicing in familial and sporadic frontotemporal dementia Archives of Neurology Sobrido MJ, Miller BL, Havlioglu N, Zhukareva V, Jiang Z, Nasreddine ZS, Lee YVM, Cummings JL, Chow TW, Wilhelmsen KC, Wu JY, Geschwind DH 1041397200 Journal Article
Randomized controlled trials in long-term care residents with dementia: a systematic review Journal of the American Medical Directors Association Mills EJ, Chow TW 1041397200 Journal Article
Frontotemporal dementias: clinical features and management Seminars in Clinical Neuropsychiatry Chow TW 1041397200 Journal Article
Therapeutic interventions for frontotemporal dementias What If It's Not Alzheimer's? A Caregiver's Guide to Frontotemporal Dementia Chow TW 1041397200 Book Chapter
PET Imaging and the Neuropsychiatry of Dementia Toronto Behavioural Neurology Section meeting Chow T 1041397200 Presentation
Is Corticobasal Ganglionic Degeneration a Frontotemporal Lobar Degeneration? Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Chow T 1041397200 Presentation
Serotonin and Frontotemporal Dementia Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Chow T 1041397200 Presentation
Dementia among American ethnic groups Workshop for American Society on Aging/National Coalition on Aging meeting Chow TW 1041397200 Presentation
Frontotemporal Dementia Recognition and Management (featured speaker) New Hampshire Alzheimer's Association Annual Conference Chow TW 1036731600 Presentation
How Close Are We to a Cure for Alzheimer's The Corinne Precourt Rubottom Lecture Chow TW 1036126800 Presentation
Medication Precautions for Alzheimer's Disease Patients ABC News Chow TW 1035954000 Presentation
Considerations in Primary Progressive Aphasia UCLA Dept of Neurology Brain Matters Seminar Chow TW 1032840000 Presentation
Functional MRI performance on semantic processing tasks in semantic dementia Frontotemporal Dementia Conference Chow TW, Adamson MM, Sungkarat W, Singh M 1031889600 Presentation
Post-surgical confusion and Alzheimer’s disease 8th International Conference on Alzheimer's Disease and Related Disorders Chow TW, Zheng L, Shigemitsu J, Mack W, Murdock G 1027137600 Presentation
Post-surgical confusion and Alzheimer's disease NEUROBIOLOGY OF AGING Chow T, Zheng L, Shigemitsu J, Mack W, Murdock G 1025496000 Abstract
Quality Indicators for Dementia Management in the Context of Asian-American Elders Kaiser Medicine Grand Rounds Chow TW 1025064000 Presentation
Emerging treatment in Mild Cognitive Impairment (MCI) and Alzheimer's disease Hong Kong Alzheimer's Disease Conference 2002 Chow TW 1019620800 Presentation
Differential Diagnosis Of Frontotemporal Dementia and AD: Clinical, Genetic, Neuropsychological And Imaging Advances Hong Kong Alzheimer's Disease Conference 2002 Chow TW 1019620800 Presentation
Frontotemporal Dementia: the Pick's of the Litter Baycrest Centre for Geriatric Care Grand Rounds Chow TW 1016773200 Presentation
Open label trial of guanfacine for symptomatic treatment of frontotemporal dementia Journal of Neuropsychiatry and Clinical Neuroscience Chow TW 1015650000 Abstract
Effect of neuropsychiatric symptoms of Alzheimer's disease on Chinese and American caregivers International Journal of Geriatric Psychiatry Pang FC, Chow TW, Cummings JL, Leung VP, Chiu HFK, Lam LCW, Chen QL, Tai CT, Chen LW, Wang SJ, Fuh JL 1009861200 Journal Article
Neuropsychiatric symptoms of Alzheimer's disease differ in Chinese and American patients International Journal of Geriatric Psychiatry Chow TW, Cummings JL, Leung VPY, Chiu HFK, Lam LCW, Chen QL, Liu CK, Tai CT, Chen LW, Wang SJ, Fuh JL 1009861200 Journal Article
Goals in symptomatic pharmacologic management of frontotemporal lobar degeneration American Journal of Alzheimer's Disease and Other Dementias Chow TW, Mendez MF 1009861200 Journal Article
Frontotemporal dementia classification and neuropsychiatry Neurologist Chow TW, Miller BL, Boone K, Mishkin F, Cummings JL 1009861200 Journal Article
Depression Parkinson's Disease: Diagnosis and Clinical Management Chow TW, Verhoeff NPLG, Takeshita S, St Jacques PL, Freedman M, Black S, Wilson A, Hussey D, Houle S, Meyer J 1009861200 Book Chapter
Gender and age at onset in frontotemporal dementia syndromes Neurology Chow TW, Hodges J, Dawson K, Miller BL, Smith V, Mendez MF 1009861200 Abstract
Neuropsychiatric Consequences of Stroke USC Dept of Psychiatry Grand Rounds Chow T 1009861200 Presentation
Gait and Cognitive Disorders of the Elderly USC Community Hospital Network Chow TW 1005195600 Presentation
Treating underserved minority Alzheimer’s disease populations 8th Annual Conference on Behavior, Clinical Neuroscience, Substance Abuse, & Culture Chow TW 1003982400 Presentation
Neuropsychiatric symptoms of Chinese and Caucasian patients with Alzheimer's disease differ Suzhou No. 2 General Hospital Grand Rounds Chow TW 1000699200 Presentation
Clinical diagnosis of the most common dementias Suzhou No. 2 General Hospital Grand Rounds Chow TW 1000699200 Presentation
A-Words in Behavioral Neurology Neuroanatomy Lecture Series, USC medical students Chow TW 990072000 Presentation
Frontotemporal Dementia Diagnosis and Management Harbor-UCLA Medical Center Department of Neurology Grand Rounds Chow TW 987739200 Presentation
Update on Interventions for Alzheimer's Disease University of Colorado Neurology Grand Rounds Chow TW 985323600 Presentation
Relational reasoning and semantic inhibition in human prefrontal cortex BRAIN AND COGNITION Morrison RG, Krawczyk D, Knowlton BJ, Holyoak KJ, Boone KB, Chow TW, Mishkin FS 984891600 Abstract
Update on Interventions for Alzheimer's Disease Celebration of Caregiving Chow TW 984718800 Presentation
Orbitofrontal and anterior cingulate cortex neurofibrillary tangle burden is associated with agitation in Alzheimer disease Annals of Neurology Tekin S, Mega MS, Masterman DM, Chow T, Garakian J, Vinters HV, Cummings JL 983422800 Journal Article
Advanced Topics in Dementia Diagnosis and Treatment for Non-Neurologists Cottage Hospital Grand Rounds Chow TW 981694800 Presentation
Review of the Dementias Rancho Los Amigos National Rehabilitation Center Grand Rounds Chow TW 979794000 Presentation
Encephalitis Lethargica: Lessons for Neuropsychiatry Psychiatric Annals Cummings JL, Chow T, Masterman D 978325200 Journal Article
Quality indicators for dementia in vulnerable community-dwelling and hospitalized elders Annals of Internal Medicine Chow TW, MacLean CH 978325200 Journal Article
Behavioral changes in subtypes of primary progressive aphasia and other frontotemporal dementias BRAIN AND COGNITION Chow TW, Boone K, Mishkin F, Miller BL 978325200 Abstract
Treating Underserved Minority Alzheimer's Disease Populations 8th Annual Conference on Behavior, Clinical Neuroscience, Substance Abuse, and Culture Chow T 978325200 Presentation
Frontotemporal Dementia: Diagnostic Features and What to Do about Them UCLA Department of Neurosciences Grand Rounds Chow TW 974264400 Presentation
Utilization of Alzheimer's disease community resources by Asian-Americans in California International Journal of Geriatric Psychiatry Chow TW, Ross L, Fox P, Cummings JL, Lin KM 967780800 Journal Article
Results of UCLA Alzheimer’s Disease Research Center Outreach to the Chinese Community of Los Angeles 5th Annual UCLA Research Conference on Aging Chow TW, Hui E, Lin J, Lu M-S, Chin P, Lin A, Sun J, Chuan J, Cham P, Chou A, Bao E, Lowe K 961560000 Presentation
Dementia associated with Amyotrophic Lateral Sclerosis Neurobase Chow TW 957844800 Journal Article
Risk factors for primary progressive aphasias: variants of frontotemporal dementia 3rd International Congress of Neuropsychiatry Chow TW, Boone K, Mishkin F, Miller BL, Ho V, Cholfin J, Geschwind DH 955252800 Presentation
Warning Signs of Alzheimer's Disease CBS Local News Chow TW 951714000 Presentation
Pedophilia and temporal lobe disturbances Journal of Neuropsychiatry & Clinical Neurosciences Mendez MF, Chow T, Ringman J, Twitchell G, Hinkin CH 946702800 Journal Article
Personality changes in frontal lobe disorders Current Psychiatry Reports Chow TW 946702800 Journal Article
Neuropsychiatry - clinical assessment and approach to diagnosis Comprehensive Textbook of Psychiatry, Sixth Edition Chow T, Cummings JL 946702800 Book Chapter
Depression in Parkinson's Disease - pharmacological characteristics and treatment Depression Associated with Medical Illness Chow TW, Cummings JL 946702800 Book Chapter
The amygdala and Alzheimer's disease The Amygdala - A Functional Analysis Chow TW, Cummings JL 946702800 Book Chapter
Xenon SPECT in classification of frontotemporal dementia subgroups Neurology Chow TW, Mendez MF, Mishkin F, Boone K, Miller BL 946702800 Abstract
Beta-Secretase and the Mouse Vaccine: Implications for Alzheimer's Disease Patients CNN Saturday Chow TW 941256000 Presentation
Identification of Beta-Secretase by Amgen NBC News Chow TW 940564800 Presentation
Identification of Beta-Secretase by Amgen Fox 11 News Chow TW 940564800 Presentation
Alzheimer’s Disease Research and the Alzheimer's Association Memory Walk Fox 11 News Chow TW 937713600 Presentation
Memory Walk Kick-Off Public Service Announcement for National Alzheimer’s Association Chow TW 936763200 Presentation
Neurological Consultation E.R. television show Chow TW 935812800 Presentation
Review of Dementias Rand Summer Institute on the Demography, Economics and Epidemiology of Aging Chow TW 930283200 Presentation
Clinical characteristics of frontotemporal dementia compared to Alzheimer’s disease Gerontological Society of America Meeting Mendez MF, Chow TW, Perryman K, Miller BL, Cummings JL 926740800 Presentation
Dementia associated with Huntington’s disease Neurobase Chow TW 926222400 Journal Article
Potential Quality Indicators and Literature Review: Dementia Assessing the Care of Vulnerable Elders (ACOVE) Chow T 926049600 Book Chapter
Inheritance of frontotemporal dementia Archives of Neurology Chow TW, Miller BL, Hayashi VN, Geschwind DH 915166800 Journal Article
Frontal-subcortical circuits Human Frontal Lobes: Functions and Disorders Chow TW, Cummings JL 915166800 Book Chapter
Recognition and treatment of Alzheimer’s disease in Los Angeles County Chinese elders 9th International Conference on Health Problems Related to Chinese in North America Chow TW, Poon G, Wei C-Y, Lin K-M, Cummings JL, Hui E, Cheung F 895032000 Presentation
Posterior cortical atrophy: Unique features Neurocase Chow T, Cummings JL 883630800 Journal Article
Drug treatment for Alzheimer's disease Western Journal of Medicine Chow T, Cummings JL 883630800 Journal Article
Depression in Parkinson's disease: Pharmacological characteristics and treatment Drugs & Aging Chow T, Cummings JL 883630800 Journal Article
Treatment of depression in the patient with Parkinson's disease Clinical Geriatrics Chow TW, Cummings JL 883630800 Journal Article
Neurobehavioral sequelae of pituitary resection Journal of Neuropsychiatry and Clinical Neurosciences Chow TW 863496000 Abstract
Improved affect, but not mood, after complex partial seizures Journal of Neuropsychiatry and Clinical Neurosciences Chow TW, Nakawatase T, Mendez M 863496000 Abstract
The clinical utilization of 18FDG-PET imaging for the diagnosis of dementia Journal of Neuropsychiatry and Clinical Neurosciences Ottowitz WE, Mendez MF, Perryman KM, Chow TW, Mandelkern MA 854773200 Abstract
Spinal decompression sickness presenting as Brown-Sequard syndrome Neurology Kimbro T, Chow T, Newman T 852094800 Journal Article
Neuroimaging characteristics in carbon monoxide toxicity Journal of Neuroimaging Chow T, Abedon S, Clark R, Wong W 820472400 Journal Article
Validation of a new instrument for determining migraine prevalence: The UCSD migraine questionnaire Neurology Chow T, Brody M, Balabhji A, Turner L, Molgaard C, Rothrock J 757400400 Journal Article
Rethinking Alzheimer's The Agenda with Steve Paikin Chow TW -28800 Presentation
. I do know how you feel: Emotion perception and comprehension in healthy aging The Inaugural Conference of the Rotman Research Institute and the Kunin-Lunenfeld Applied Research Unit Gillingham S, Binns MA, Craik FIM, Chow TW, Nguyen C, Alter L, Stuss DT -28800 Presentation

Education

  • 1992: M.D., Alternative Curriculum , Rush Medical College Chicago, Illinois, USA
  • 1988: M.Sc., Marine Biology, Stanford University Stanford, California, USA
  • 1987: B.A., B.Sc., German Studies, Biological Sciences, Stanford University Stanford, California, USA
  • 1983: Undeclared Major, High School Scholar , UCLA Los Angeles, California, USA

Academic Appointments

  • 2010–Present: Senior Scientist, Rotman Research Institute, Behavioural Neurology, Dept of Medicine, Baycrest, Toronto, Ontario, Canada
  • 2003–Present: Assistant Professor of Neurology , Department of Medicine, Neurology Division, University of Toronto, Toronto, Ontario, Canada
  • 2006–Present: Assistant Professor of Psychiatry, Department of Medicine, Geriatric Psychiatry Division, University of Toronto, Toronto, Ontario, Canada
  • 2000–2003: Director , Frontotemporal Dementia Clinic, University of Southern California, California, USA
  • 2000–2003: Director Translational Core of Rancho Los Amigos, Alzheimer's Disease Center, University of Southern California, California, USA
  • 2000–2003: Assistant Professor, Neurology , University of Southern California, California, USA
  • 2003–2010: Clinician-Scientist, Rotman Research Institute, Baycrest

Professional Affiliations

Distinctions and Awards

  • 2009: First Women of Baycrest-Supported Scientist
  • 2005: Dean's Fund for New Faculty, University of Toronto
  • 2000: Alzheimer's Disease Research Scholar, Deane Johnson Foundation
  • 1999: Turken Award for Junior Investigator in Alzheimer's Disease Research, Alzheimer's Association, 10,000
  • 1997: Selection for the NIA-supported Summer Research Institute, NIA
  • 1996: Kaiser Permanente Housestaff Teaching Award, UCSD, voted by UCSD third and fourth year medical students
  • 1996: Golden Neuron Award for Teaching Medical Students, UCSD Neurology Department
  • 1996: Annual Meeting Scholarship for Residents, American Academy of Neurology
  • 1995: Chief Resident, Neurology, UCSD
  • 1995: Golden Diaper Award, UCSD Pediatric Neurology Department, For performance on pediatric neurology rotation
  • 1994: Kaiser Permanente Housestaff Teaching Award, UCSD
  • 1994: Golden Neuron Award for Teaching Medical Students, UCSD Neurology Department
  • 1991: Joseph Collins Foundation Scholarship, Joseph Collins Foundation
  • 1991: Theresa M. Knorr Memorial Award, American Medical Women's Association
  • 1987: Award for Exceptional Achievement in Teaching, Stanford University

Research Projects

External

  • 2007–2010: Open-Label Study of Memantine on FDG-PET in Frontotemporal Dementia
    Institutions: Baycrest, CAMH

    Sponsors: Lundbeck Research Grant

  • 2002–2005: PET Serotonin Studies in Frontotemporal Dementia
    Collaborators: Tiffany Chow MD; Sandra Black, MD, FRCPC; Paul Verhoeff, MD,PhD, FRCPC; Jeff Meyer, MD, PhD, FRCPC;Morris Freedman
    Institutions: University of Toronto

    Sponsors: NIA, 162,000 (USD)

  • 2004–2009: Frontal Aging Study
    Collaborators: Donald Stuss PhD, C Psych; Tiffany Chow MD

    Sponsors: CIHR

  • 2003–2005: Supporting Caregivers of Patients with Frontotemporal Dementia
    Collaborators: Elsa Marziali
    Institutions: KLARU
  • 2001–2003: Assessing Barriers to Dementia Care among Asian Communities in Southern California: Primary Care Provider Survey

    Sponsors: Pfizer Research Grant

  • 2001–2003: Frontotemporal Dementia Consortium: Multi-Center Alzheimer's Research Centre of California Study
    Collaborators: Bruce Miller, Kirk WIlhelmsen, Mario Mendez
    Institutions: UC:LA, UCSF

    Sponsors: Alzheimer's Research Centers of California

  • 2001–2003: Depression in Alzheimer's Disease: Multi-Center ARCC Study
    Collaborators: Bruce Miller, Jeffrey Cummings
    Institutions: UC Davis, UCLA, UCSF, USC, UC Irvine

    Sponsors: Alzheimer's Research Centers of California

  • 2001–2003: Assessing Barriers to Dementia Care among Asian Communities in Southern California: Community Focus Groups
    Collaborators: Tiffany Chow MD
    Institutions: USC, Rancho Los Amigos

    Sponsors: Pfizer, Inc., 68000 (USD)

  • 1998–2003: Investigating the Neural Substrates of Reasoning: Studies with Dementia Patients
    Collaborators: Barbara Knowlton PhD at UCLA Dept of Psych
    Institutions: UCLA, USC
  • 2002: Language Processing in Semantic Dementia and Functional MRI
    Collaborators: Tiffany Chow MD
    Institutions: USC, Rancho Los Amigos National Rehabilitation Center
  • 2000–2002: Open Label Trial of Guanfacine for Symptomatic Treatment of Frontotemporal Dementia
    Institutions: USC, Rancho Los Amigos
  • 2002: Open Label Use of Amantadine for Symptomatic Treatment of Non-Fluent Primary Progressive Aphasia
    Institutions: USC, Rancho Los Amigos
  • 2011–2012: When Dementia Is in the House
    Collaborators: Kenneth Rockwood
    Institutions: Baycrest, Dalhousie, CDKTN

    Sponsors: AFP Innovation Grant, 10,150 (CAD)

    Research Grant
  • 2011–2012: When Dementia Is in the House
    Collaborators: Kenneth Rockwood
    Institutions: Baycrest. Dalhousie, CDKTN

    Sponsors: Canadian Dementia Knowledge Translation Network, 24,820 (CAD)

    Research Grant
  • 2011–2013: Relation of beta-amyloid to temporal variant frontotemporal dementia
    Collaborators: Ariel Graff-Guerrero, Zahinoor Ismail, Sylvain Houle, Alan Wilson, Bruce Pollock, Benoit Mulsant
    Institutions: Baycrest, CAMH

    Sponsors: NIA, $98,366 (US)

    Research Grant

Internal

  • 2010–2011: RELATION OF CHOLINERGIC RECEPTOR CHANGES TO DEVELOPMENT OF ALZHEIMER'S DISEASE
    Collaborators: Peter Bloomfield, Sylvain Houle, Zahinoor Ismail, Benoit Mulsant, Bruce Pollock, Pablo Rusjan, Neil Vasdev, Alan Wilson
    Institutions: Baycrest, CAMH

    Sponsors: CAMH Geriatric Mental Health Program

  • 2009–2012: Resting State Functional Connectivity in Frontotemporal Dementia
    Collaborators: Cheryl Grady, Steve Strother

    Sponsors: Moir Family Fund

  • 2010–2011: RELATION OF BETA-AMYLOID DEPOSITION TO PSYCHIATRIC DISTURBANCE IN DEMENTIA
    Collaborators: Sylvain Houle, Zahinoor Ismail, Benoit Mulsant, Bruce Pollock, Alan Wilson
    Institutions: Baycrest, CAMH

    Sponsors: CAMH Geriatric Mental Health Program

Media Coverage

May 15, 2011, CTV Avis Ferraro Health News re Lewy Body Dementia

Jan 2011 CTV Avis Ferraro Health News re Frontotemporal Dementia

Women of Baycrest

"Forgetful, not Forgotten," TVO Panel Discussion, aired live across Canada and through webcast January 11, 2009
"The Rising Tide of Alzheimer's Disease," CBC World News, across Canada January 5, 2009

"Ginkgo no help for preventing Alzheimer's: Study, The National, CBC, across Canada. November 18, 2008

"Rethinking Alzheimer's," The Agenda with Steve Paikin, TVO, Toronto. April 21, 2008

Neurological Consultant for episodes on a physician (Alan Alda) impaired by Alzheimer's disease, E.R. television show, aired Oct.-Nov. 1999, 1999;

Curriculum Vitae

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