Verhoeff, Paul Dr.
Paul Verhoeff, MD, PhD, FRCPC
Associate Professor of Psychiatry Department of Psychiatry, Geriatric Program, University of Toronto
Staff Psychiatrist Brain Health Centre, Behavioural Neurology Memory Disorders Clinic, and Geriatric Psychiatry Community Service, Baycrest Centre for Geriatric Care
Neuropsychiatry Clinician-Scientist and Staff Psychiatrist Kunin-Lunenfeld Applied Research Unit, Geriatric Psychiatry Community Service, Baycrest Centre for Geriatric Care
more- Cerebral β-Amyloid imaging with PET in patients with Alzheimer’s disease (2001-present) and with SPECT in patients with amyloid angiopathy (1991-1996).
- Neostriatal dopamine D2 receptor imaging with PET in patients with schizophrenia and in healthy subjects before and after catecholamine depletion with α-methyl-para-tyrosine (1999-2001), in patients with schizophrenia off and on antipsychotics (1999-2004), and in patients with major depressive disorder (2001-2004), bipolar disorder (1997-2000); with SPECT in patients with Tourette disorder (1990-1994), partial epilepsy (1991-1994), Parkinsonian syndromes (1990-1993), pituitary macroadenomas (1990-1993), migraine (1990-1993), HIV encephalopathy (1990-1991), in patients with schizophrenia off and on antipsychotics (1990-1995), in healthy subjects (1990-1993), and in MPTP-treated and control nonhuman primates (1990-1994); with a planar gamma-camera for dosimetry in healthy subjects (1990-1993); ex vivo in rodents (1988-1991); and in vitro in humans and rodent brain tissues (1988-1991).
- Extrastriatal dopamine D2 receptor imaging with SPECT in healthy subjects (1997-2000).
- Neostriatal dopamine D1 receptor imaging with PET in healthy subjects before and after catecholamine depletion with α-methyl-para-tyrosine (1999-2001); and with SPECT in healthy subjects (1991-1993).
- Cerebral serotonin 5-HT1A receptor imaging with PET in patients with Alzheimer’s disease (2001-present), frontotemporal dementia (2001-present), and schizophrenia (1999-2003), and in healthy subjects (1999-2001).
- Cerebral serotonin 5-HT2A receptor imaging with PET in patients with schizophrenia (1999-2000).
- Cerebral GABAA-benzodiazepine receptor imaging with SPECT in patients with alcohol dependence (1997-2004), post-traumatic stresss disorder (1997-2004), major depressive disorder (1997-2003), schizophrenia (1994-1999), epilepsy (1994-1999), and in healthy subjects off and on benzodiazepines (1988-1999).
- Cerebral muscarinic acetylcholinergic mACh receptor imaging with SPECT ex vivo in rats (1988-1993).
- Pituitary somatostatin receptor imaging with SPECT in patients with pituitary adenomas and in healthy subjects (1992-1996).
- Cerebral blood flow imaging with SPECT in patients with Alzheimer’s disease (1988-1992), partial epilepsy (1988-1992), and ischemic stroke (1988-2001).
- Physiological measurements of early and late asthmatic responses to submaximal exercise challenge before and after nedocromil sodium in patients with intrinsic and extrinsic bronchial asthma (1988-1990).
Research Focus
Most of my research activities have centered around neuroreceptor imaging in vivo with positron emission tomography (PET) or single-photon computerized tomography (SPECT) in patients with neuropsychiatric disorders and in healthy control subjects. The research projects are listed according to the neurochemical transmission systems that have been studied, with further clarification as to which patient groups were involved during which period:
Publications
| Title | Source (Journal/Book/Conference) | Authors/Presenters | Published On | Type |
|---|---|---|---|---|
| An [11C]SB-13 PET study correlating neuropsychiatric symptoms in Alzheimer’s disease with regional beta-amyloid burden | Psychiatry Research: Neuroimaging | Kaye ED, Honjo K, Petrovic-Poljak A, Reekum R, Streiner DL, Wilson AA, Black SE, Freedman M, Rusjan P, Houle S, Chow TW, Verhoeff NPLG | 1325307600 | Journal Article |
| Amyloid imaging with [11C]SB-13 PET: a test-retest reliability study | 36th Annual Harvery Stancer Research Day | Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black S | 1303963200 | Presentation |
| Amyloid Imaging with [11C]SB-13 PET: A Test-Retest Reliability Study | Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black S | 1278734400 | Presentation | |
| Amyloid imaging with [11C]SB-13 PET: A test-retest reliability study | ALZHEIMER'S & DEMENTIA | Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black SE | 1278734400 | Abstract |
| Correlating neuropsychiatric symptoms with cerebral beta-amyloid load in mild Alzheimer's disease using [11C]SB-13 PET | Kaye ED, Honjo K, Petrovic-Poljak A, van Reekum R, Streiner DL, Wilson A, Black SE, Freedman M, Rusjan P, Houle S, Verhoeff NPLG | 1276747200 | Presentation | |
| Frontotemporal dementia and pharmacologic interventions | Journal of Neuropsychiatry and Clinical Neurosciences | Kaye ED, Petrovic-Poljak A, Verhoeff NP, Freedman M | 1265000400 | Journal Article |
| Commentary on the letter for Alzheimer’s disease and infection: Do infectious agents contribute to progression of Alzheimer’s disease? | Alzheimer’s & Dementia | Honjo K, Van Reekum R, Verhoeff NPLG | 1262322000 | Journal Article |
| Correlating neuropsychiatric symptoms with regional Beta-Amyloid load in the Alzheimer’s Disease brain using [11C]SB-13 PET | Kaye E, Honjo K, Petrovic-Poljak A, van Reekum R, Streiner D, Wilson A, Black S, Freedman M, Rusjan P, Houle S, Verhoeff P | 1258088400 | Presentation | |
| Does Beta-Amyloid correlate with neuropsychiatric symptoms in mild Alzheimer’s Disease? | Kaye E, Honjo K, Petrovic-Poljak A, van Reekum R, Streiner D, Wilson A, Black S, Freedman M, Rusjan P, Houle S, Verhoeff P | 1258088400 | Presentation | |
| Functional outcome in delusional Alzheimer Disease patients - A systematic review | Dementia and Geriatric Cognitive Disorders | Fischer CE, Verhoeff NPLG, Churchill K, Schweizer TA | 1254974400 | Journal Article |
| Pre-and post-memantine FDG-PET imaging in frontotemporal dementia | 5th Canadian Conference on Dementia | Chow TW, Binns MA, Freedman M, Pollock BG, Verhoeff NP, Graff-Guerrero A | 1254369600 | Presentation |
| Amyloid Imaging with [11C]SB-13 PET: A Test-Retest Reliability Study | CANADIAN JOURNAL OF GERIATRICS | Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black S | 1254369600 | Abstract |
| Pre- and post-memantine FDG-PET imaging in frontotemporal dementia | 5th Canadian Conference on Dementia | Chow TW, Binns MA, Freedman M, Pollock B, Verhoeff NPLG, Graff-Guerrero A | 1254369600 | Presentation |
| Alzheimer's disease and infection: do infectious agents contribute to progression of Alzheimer's disease? | Alzheimer’s & Dementia | Honjo K, Van Reekum R, Verhoeff NPLG | 1246420800 | Journal Article |
| Amyloid imaging with [11C]SB-13 PET: a test-retest reliability study | 35th Annual Harvery Stancer Research Day | Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black S | 1245902400 | Presentation |
| Correlating neuropsychiatric symptoms with regional beta-amyloid load in the Alzheimer’s disease brain using [11C]SB-13 PET | UNIVERSITY OF TORONTO DEPARTMENT OF PSYCHIATRY | Kaye ED, Honjo K, Petrovic-Poljak A, Van Reekum R, Streiner D, Wilson AA, Black SE, Freedman M, Rusjan P, Houle S, Verhoeff NPLG | 1245902400 | Abstract |
| Correlating neuropsychiatric symptoms with regional beta-amyloid load in the Alzheimer’s disease brain using [11C]SB-13 PET | CANADIAN JOURNAL OF GERIATRICS | Kaye ED, Honjo K, Petrovic-Poljak A, Van Reekum R, Streiner D, Wilson AA, Black SE, Freedman M, Rusjan P, Houle S, Verhoeff NPLG | 1240632000 | Abstract |
| Pre- and post-memantine FDG-PET imaging in frontotemporal dementia | AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY | Chow T, Binns M, Dombrower H, Freedman M, Verhoeff P, Pollock BG | 1236229200 | Abstract |
| Pre- and post-memantine FDG-PET imaging in frontotemporal dementia. | AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY | Chow TW, Binns MA, Freedman M, Pollock B, Verhoeff NPLG, Graff-Guerrero A | 1236229200 | Abstract |
| A positron emission tomography study of 5-hydroxytryptamine-1A receptors in Alzheimer disease | American Journal of Geriatric Psychiatry | Lanctot KL, Hussey DF, Herrmann N, Black SE, Rusjan PM, Wilson AA, Houle S, Kozloff N, Verhoeff NP, Kapur S | 1191211200 | Journal Article |
| Comparison of manual and semi-automated delineation of regions of interest for radioligand PET imaging analysis | BMC Nuclear Medicine | Chow TW, Takeshita S, Honjo K, Pataky CE, St Jacques PL, Kusano ML, Caldwell CB, Ramirez J, Black S, Verhoeff NPLG | 1167627600 | Journal Article |
| PET and SPECT imaging in psychiatric disorders | Canadian Journal of Psychiatry | Zipursky RB, Meyer JH, Verhoeff NP | 1167627600 | Journal Article |
| Frontal-subcortical circuits and a rationale for neuroreceptor quantification in FTD | NEUROPSYCHOPHARMACOLOGY | Chow T, Rusjan P, Meyer J, Verhoeff NP, Pollock BG, Smith G | 1165122000 | Abstract |
| Elevated putamen D2 receptor binding potential in major depression with motor retardation: An [11C]raclopride Positron Emission Tomography study | American Journal of Psychiatry | Meyer JH, McNeely HE, Sagrati S, Boovariwala A, Martin K, Verhoeff NPLG, Wilson AA, Houle S | 1157083200 | Journal Article |
| Left orbitofrontal atrophy correlates with disinhibition and apathy in frontotemporal degeneration | ALZHEIMER’S & DEMENTIA | Chow TW, Binns MA, Freedman M, Stuss DT, Ramirez J, Verhoeff NPLG, Black SE | 1153022400 | Abstract |
| Alzheimer's disease and cerebrovascular disease - links with amyloid beta protein | Kunin-Lunenfeld Applied Research Unit Rounds | Honjo K, Verhoeff NPLG | 1136091600 | Presentation |
| What relevant aspects of the beta-amyloid cascade do we image with [11C]SB-13 PET? | Neuroscience Rounds at at Sunnybrook and Women's College Health Sciences Centre | Verhoeff NPLG, Honjo K | 1136091600 | Presentation |
| Nuclear medicine: how can it help to optimize treatment for schizophrenia? | Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1136091600 | Presentation |
| Agitation and psychotic disorders in the elderly | Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1136091600 | Presentation |
| Alcohol and substance abuse in the elderly | Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1136091600 | Presentation |
| Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade | PET Centre Seminars at the Centre for Addiction and Mental Health, Clarke Site | Verhoeff NPLG | 1136091600 | Presentation |
| Nuclear medicine: how can it help to optimize treatment for schizophrenia? | Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1136091600 | Presentation |
| Alzheimer's disease and cerebrovascular disease - links with amyloid beta protein | Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care | Honjo K, Verhoeff NPLG | 1136091600 | Presentation |
| Alzheimer disease (AD) and cerebrovascular disease (CVD) - links with amyloid beta protein | Grand Rounds at the Department of Geriatric Psychiatry | Honjo K, Verhoeff NPLG | 1136091600 | Presentation |
| Effect of subthalamic stimulation on mood state in Parkinson's disease: evaluation of previous facts and problems | Neurosurgical Review | Takeshita S, Kurisu K, Trop L, Arita K, Akimitsu T, Verhoeff NPLG | 1120190400 | Journal Article |
| Antidepressants: Mechanism of action | Geriatrics and Aging | Verhoeff NPLG | 1104555600 | Journal Article |
| Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking | Archives of General Psychiatry | Staley JK, Gottschalk C, Petrakis IL, Gueorguieva R, O'Malley S, Baldwin R, Jatlow P, Verhoeff NP, Perry E, Weinzimmer D, Frohlich E, Ruff E, van Dyck CH, Seibyl JP, Innis RB, Krystal JH | 1104555600 | Journal Article |
| Acetylcholinergic neurotransmission and the β-amyloid cascade: Implications for Alzheimer's disease | Expert Review of Neurotherapeutics | Verhoeff NPLG | 1104555600 | Journal Article |
| Reduced serotonin 1a receptor binding potential and abnormal oral behaviors in frontotemporal degeneration | Neurology | Chow TW, Verhoeff NPLG, Takeshita S, Freedman M, Black S, Wilson A, Hussey D, Houle S, Meyer J | 1104555600 | Abstract |
| Traumatic brain injury and Alzheimer's disease | Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Van Reekum R, Verhoeff NPLG | 1104555600 | Presentation |
| Traumatic brain injury and Alzheimer's disease | Rotman Rounds | Rapoport M, Van Reekum R, Verhoeff NPLG | 1104555600 | Presentation |
| What relevant aspects of the beta-amyloid cascade do we image with [11C]SB-13 PET? | PET Centre Seminars at the Centre for Addiction and Mental Health, Clarke Site | Honjo K, Verhoeff NPLG | 1104555600 | Presentation |
| Nuclear medicine: how can it help to optimize treatment for schizophrenia? | Annual Scientific Congress of the European Association of Nuclear Medicine | Verhoeff NPLG | 1104555600 | Presentation |
| Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade | Department of Geriatric Psychiatry Grand Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1104555600 | Presentation |
| Agitation and psychotic disorders in the elderly | Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1104555600 | Presentation |
| Neurological Examination for Psychiatrists | Geriatric Psychiatry Residents' Seminar Day, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1104555600 | Presentation |
| In vivo imaging of Alzheimer's disease beta-amyloid with [11C]SB-13 PET | 31st Annual Harvey Stancer Research Day | Verhoeff NPLG | 1104555600 | Presentation |
| Formulation Seminar for Geriatric Psychiatry Residents | Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1104555600 | Presentation |
| Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade | Neuroscience Rounds at at Sunnybrook and Women's College Health Sciences Centre | Verhoeff NPLG | 1104555600 | Presentation |
| Cortical GABAA/Benzodiazepine Receptors in Recovery from Alcohol Dependence: Relationship to Features of Alcohol Dependence and Cigarette Smoking | Addiction Psychiatry Rounds at the Centre for Addiction and Mental Health | Verhoeff NPLG | 1104555600 | Presentation |
| Is there evidence from prospective cohort studies that apolipoprotein E epsilon 4 allele status affects the likelihood that traumatic brain injury will be followed by Alzheimer's disease? | Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1104555600 | Presentation |
| Effects of catecholamine depletion on D2 receptor binding, mood, attentiveness and personality in humans | Rounds at the Department of Behavioural Neurology, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1104555600 | Presentation |
| Cortical GABAA/benzodiazepine receptors in recovery from alcohol dependence: Relationship to features of alcohol dependence and cigarette smoking | Kunin-Lunenfeld Applied Research Unit Rounds | Verhoeff NPLG | 1104555600 | Presentation |
| Traumatic Brain Injury and Dementia Symposium | American Association for Geriatric Psychiatry's 2005 Annual Meeting | Rapoport MJ, Verhoeff NPLG, van Reekum R | 1104555600 | Presentation |
| Dopamine and psychomotor retardation in depression | Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1104555600 | Presentation |
| Alcohol and substance abuse in the elderly | Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1104555600 | Presentation |
| Benzodiazepine Receptor Imaging in Geriatric Neuropsychiatric Disorders | Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1104555600 | Presentation |
| In-vivo imaging of Alzheimer disease beta-amyloid with [C-11]SB-13 PET | American Journal of Geriatric Psychiatry | Verhoeff NPLG, Wilson AA, Takeshita S, Trop L, Hussey D, Singh K, Kung HF, Kung MP, Houle S | 1099285200 | Journal Article |
| Depression in frontotemporal dementia is associated with decreased left temporal lobe 5HT1a receptor density | ANNALS OF NEUROLOGY | Chow TW, Verhoeff NPLG, Takeshita S, St Jacques PL, Freedman M, Black SE, Wilson A, Hussey D, Houle S, Meyer J | 1096862400 | Abstract |
| Reduced serotonin 1a receptors in depressed frontotemporal lobar degeneration subjects | Symposium for Frontotemporal Dementia | Chow TW, Verhoeff NPLG, Takeshita S, Freedman M, Black SE, Wilson A, Hussey D, Houle S, Meyer J | 1089691200 | Presentation |
| Equivalent occupancy of dopamine D1 and D2 receptors with clozapine: differentiation from other atypical antipsychotics. | American Journal of Psychiatry | Tauscher J, Hussain T, Agid O, Verhoeff NP, Wilson AA, Houle S, Remington G, Zipursky RB, Kapur S | 1072933200 | Journal Article |
| Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder. | Biological Psychiatry | Fujita M, Southwick SM, Denucci CC, Zoghbi SS, Dillon MS, Baldwin RM, Bozkurt A, Kugaya A, Verhoeff NP, Seibyl JP, Innis RB | 1072933200 | Journal Article |
| Equivalent occupancy of dopamine D1 and D2 receptors differentiates clozapine from other atypicals | American Journal of Psychiatry | Tauscher J, Hussain T, Agid O, Verhoeff NPLG, Wilson AA, Houle S, Remington G, Zipursky RB, Kapur S | 1072933200 | Journal Article |
| Ligands for neuroreceptor imaging by positron or single-photon emission tomography | Nuclear Medicine in Clinical Diagnosis and Treatment | Verhoeff NPLG | 1072933200 | Book Chapter |
| I-Amyloid imaging in vivo and its possible implications for Alzheimer's disease | Nuclear Medicine in Psychiatry | Verhoeff NPLG, Wilson AA, Kung HF, Hussey D, Trop L, Houle S | 1072933200 | Book Chapter |
| Patient with visual hallucinations | Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG, Mamelak M | 1072933200 | Presentation |
| Agitation and psychotic disorders in the elderly | Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1072933200 | Presentation |
| Beta-amyloid PET study: second progress report | Neuroscience Rounds at Sunnybrook and Women's College Health Sciences Centre | Verhoeff NPLG | 1072933200 | Presentation |
| Does hypothyroidism cause Alzheimer's disease? | Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1072933200 | Presentation |
| Beta-amyloid PET study: Second progress report | Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site | Verhoeff NPLG | 1072933200 | Presentation |
| The role of GABA in depression: cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT | Kunin-Lunenfeld Applied Research Unit Rounds | Verhoeff NPLG | 1072933200 | Presentation |
| The role of GABA in depression: cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT | Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1072933200 | Presentation |
| Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade | Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1072933200 | Presentation |
| The role of GABA in PTSD: Central type benzodiazepine receptors in Gulf war veterans with post-traumatic stress disorder | Department of Geriatric Psychiatry Grand Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1072933200 | Presentation |
| Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade | Kunin-Lunenfeld Applied Research Unit Rounds | Verhoeff NPLG | 1072933200 | Presentation |
| Beta-amyloid PET study: second progress report | Kunin-Lunenfeld Applied Research Unit Rounds | Verhoeff NPLG | 1072933200 | Presentation |
| Does traumatic brain injury induce cerebral beta-amyloidosis and does genetic ApoE status affect this induction? | Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1072933200 | Presentation |
| Alcohol and substance abuse in the elderly | Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1072933200 | Presentation |
| The role of GABA in depression: cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT | Beta-amyloid PET study: second progress report | Verhoeff NPLG | 1072933200 | Presentation |
| Beta-amyloid PET study: first progress report | Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1072933200 | Presentation |
| [11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? | Rotman Rounds | Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, St George-Hyslop P, Head E, Hussey D, Takeshita S, Trop L, Tapp D, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S | 1072933200 | Presentation |
| Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT. | Biological Psychiatry | Kugaya A, Sanacora G, Verhoeff NP, Fujita M, Mason GF, Seneca NM, Bozkurt A, Khan SA, Anand A, Degen K, Charney DS, Zoghbi SS, Baldwin RM, Seibyl JP, Innis RB | 1066190400 | Journal Article |
| 11C-Labeled Stilbene Derivates as Aβ-aggregate-specific PET Imaging Agents for Alzheimer's disease | Nuclear Medicine and Biology | Ono M, Wilson A, Nobrega J, Westaway D, Verhoeff NPLG, Zhuang ZP, Kung MP, Kung HF | 1059710400 | Journal Article |
| Effects of catecholamine depletion on D2 receptor binding and mood in healthy humans | Brain and Cognition | Verhoeff NPLG, Hussey D, Lee M, Christensen BK, Papatheodorou G, Zipursky RB, Kapur S | 1046494800 | Journal Article |
| Effects of catecholamine depletion on D2 receptor binding, mood and attentiveness in humans: A replication study | Pharmacology, Biochemistry and Behavior | Verhoeff NPLG, Christensen BK, Hussey D, Lee M, Papatheodorou G, Kopala L, Rui Q, Zipursky RB, Kapur S | 1041397200 | Journal Article |
| Imaging antipsychotic action at dopamine receptors | Dopamine Receptors and Transporters 2nd Edition | Verhoeff NPLG, Kapur S | 1041397200 | Book Chapter |
| Do NSAIDs reduce the risk of developing AD? | Canadian Academy of Geriatric Psychiatry Bulletin | Verhoeff NPLG | 1041397200 | Journal Article |
| Serotonergic dysfunctions in schizophrenia | Handbook of Medical Psychiatry | Tauscher J, Verhoeff NPLG | 1041397200 | Book Chapter |
| Management of Agitation and Aggression in the Elderly | Psychogeriatric Update 2003 at the Joseph E. and Minnie Wagman Centre, Baycrest Centre for Geriatric Care | Verhoeff NPLG, Meier R, Mangar M, Wilkie T | 1041397200 | Presentation |
| [11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? | Neuroscience Rounds at Sunnybrook and Women's College Health Sciences Centre | Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S | 1041397200 | Presentation |
| [11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? | PET Centre Seminars at the Centre for Addiction and Mental Health, Clarke Site | Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S | 1041397200 | Presentation |
| [11C]SB-13 PET: A valid alternative for beta-amyloid imaging in vivo? | Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S | 1041397200 | Presentation |
| [11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? | Department of Geriatric Psychiatry Grand Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S | 1041397200 | Presentation |
| [11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? | Kunin-Lunenfeld Applied Research Unit Rounds | Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S | 1041397200 | Presentation |
| Can beta-amyloid PET assist in the prediction which Mild Cognitive Impairment patients will develop Alzheimer's disease? | Evidence Based Clinical Practice Seminars | Verhoeff NPLG | 1041397200 | Presentation |
| [11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? | Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site | Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S | 1041397200 | Presentation |
| [11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? | VIth International Conference on Quantification of Brain Function with PET organized by the Society for Cerebral Blood Flow and Metabolism | Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S | 1041397200 | Presentation |
| Development of positron emission tomography tracers for beta-amyloid imaging in vivo and its possible implications for management of Alzheimer's disease | Facilitating the Development of PET Diagnostics for Alzheimer's Disease | Verhoeff NPLG | 1041397200 | Presentation |
| AMPT-induced catecholamine depletion in schizophrenic patients and control subjects | Rotman Rounds | Verhoeff NPLG | 1041397200 | Presentation |
| Is it likely that cholinesterase inhibitors (AChEI) decrease Abeta aggregation in Alzheimer's disease patients? | Evidence Based Clinical Practice Seminars | Verhoeff NPLG | 1041397200 | Presentation |
| Psychotic disorders in the elderly | Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1041397200 | Presentation |
| Beta-amyloid imaging in vivo | Neuro-Geriatric Psychiatry Lecture Series at the Centre for Addiction and Mental Health, Queen Street Site | Verhoeff NPLG | 1041397200 | Presentation |
| Beta-amyloid imaging in vivo | Grand Rounds at Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1041397200 | Presentation |
| PET imaging of D1 and D2 receptors during treatment with novel antipsychotics | European Neuropsychopharmacology | Tauscher J, Agid O, Verhoeff NPLG, Harris P, Zipursky RB, Kapur S | 1033444800 | Abstract |
| Brain serotonin 5-HT1A receptor binding in schizophrenia measured by Positron Emission Tomography and [11C]WAY-100635 | Archives of General Psychiatry | Tauscher J, Kapur S, Verhoeff NPLG, Hussey DF, Daskalakis ZJ, Tauscher-Wisniewski S, Wilson AA, Houle S, Kasper S, Zipursky RB | 1022904000 | Journal Article |
| Dopamine depletion results in increased neostriatal D(2), but not D(1), receptor binding in humans | Molecular Psychiatry | Verhoeff NPLG, Hussey D, Lee M, Tauscher J, Papatheodorou G, Wilson AA, Houle S, Kapur S | 1009861200 | Journal Article |
| Depression | Parkinson's Disease: Diagnosis and Clinical Management | Chow TW, Verhoeff NPLG, Takeshita S, St Jacques PL, Freedman M, Black S, Wilson A, Hussey D, Houle S, Meyer J | 1009861200 | Book Chapter |
| Pharmacotherapy of agitation and psychotic symptoms in Alzheimer's disease | Expert Review of Neurotherapeutics | Verhoeff NPLG | 1009861200 | Journal Article |
| Dopamine depletion results in increased neostriatal D2 receptor binding in humans | Molecular Psychiatry | Verhoeff NPLG, Tauscher J, Jones C, Hussey D, Lee M, Papatheodorou G, Wilson AA, Houle S, Kapur S | 1009861200 | Journal Article |
| AMPT-induced catecholamine depletion in schizophrenic patients and control subjects | Kunin-Lunenfeld Applied Research Unit Rounds | Verhoeff NPLG | 1009861200 | Presentation |
| Do NSAIDs reduce the risk of developing Alzheimer's disease? | Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1009861200 | Presentation |
| Beta-amyloid imaging in vivo | Kunin Lunenfeld Applied Research Unit 2nd Annual Conference on Alzheimer and Related Dementias: The Prevention of Disease, Morbidity, and Suffering | Verhoeff NPLG | 1009861200 | Presentation |
| AMPT-induced catecholamine depletion in schizophrenic patients and control subjects | Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site | Verhoeff NPLG | 1009861200 | Presentation |
| Psychotic disorders in the elderly | Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1009861200 | Presentation |
| Cortical GABAA/Benzodiazepine Receptors in Recovery from Alcohol Dependence: Relationship to Features of Alcohol Dependence and Cigarette Smoking | Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1009861200 | Presentation |
| Dopamine depletion in healthy subjects and in schizophrenic patients | Educational Evening of the Behavioural Neurology Section of the Division of Neurology, University of Toronto | Verhoeff NPLG | 1009861200 | Presentation |
| Effects of catecholamine depletion on D2 receptor binding, mood, attentiveness and personality in humans | Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1009861200 | Presentation |
| Patient with prominent cognitive and mood symptoms | Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 1009861200 | Presentation |
| A simple method to measure baseline occupancy of neostriatal dopamine D2 receptors by dopamine in vivo in healthy subjects | Neuropsychopharmacology | Verhoeff NPLG, Kapur S, Hussey D, Lee M, Christensen B, Papatheodorou G, Zipursky RB | 996638400 | Journal Article |
| Sensitivity of Voxel Based Comparisons for PET ligands with SPM | Neuroimage | Hussey D, Meyer JH, Kapur S, Verhoeff NPLG, Tauscher J, Cheung K, Houle S | 991368000 | Abstract |
| Serotonin 5-HT 1A receptor bnding potential declines with age as measured by [ 11 C]WAY-100635 and PET | Neuropsychopharmacology | Tauscher J, Verhoeff NPLG, Christensen B, Hussey D, Meyer JH, Kecojevic A, Javanmard M, Kasper S, Kapur S | 988689600 | Journal Article |
| Imaging of dopaminergic transmission in neuropsychiatric disorders | Current Opinion in Psychiatry | Verhoeff NPLG | 988689600 | Journal Article |
| PET imaging of serotonin 5-HT1A receptors in schizophrenia | Schizophrenia Research | Tauscher J, Kapur S, Verhoeff NP, Daskalakis ZJ, Tauscher-Wisniewski S, Papatheodorou G, Zipursky RB | 987307200 | Abstract |
| Neuroimaging and antipsychotics | Journal of Pharmacy Practice | Verhoeff NPLG, Kapur S | 978325200 | Journal Article |
| Radiotracer imaging of dopamine transporters and presynaptic dopamine synthesis in parkinsonian syndromes | Brazilian Journal of Psychiatry | Verhoeff NPLG | 978325200 | Journal Article |
| Efficacy and adverse effect rates of antipsychotics for agitation and psychosis in elderly patients with AD | Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 978325200 | Presentation |
| A voxel-by-voxel analysis of [18F]setoperone PET data shows no substantial serotonin 5-HT receptor 2A changes in schizophrenia | Psychiatry Research: Neuroimaging | Verhoeff NPLG, Meyer J, Kecojevic A, Hussey D, Lewis R, Tauscher J, Zipursky RB, Kapur S | 972882000 | Journal Article |
| Test-retest reproducibility of extrastriatal dopamine D2 receptor imaging with [123I]epidepride SPECT in humans. | Journal of Nuclear Medicine | Varrone A, Fujita M, Verhoeff NP, Zoghbi SS, Baldwin RM, Rajeevan N, Charney DS, Seibyl JP, Innis RB | 965102400 | Journal Article |
| Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients | American Journal of Psychiatry | Anand A, Verhoeff NPLG, Seneca N, Zoghbi SS, Seibyl JP, Charney DS, Innis RB | 962424000 | Journal Article |
| Linear regression analysis for PET/SPECT quantification of reversible neuroreceptor binding | JOURNAL OF NUCLEAR MEDICINE | Ichise M, Burger C, Stundzia A, Meyer JH, Verhoeff NP, Yonekura Y | 960004800 | Abstract |
| A voxel-by-voxel analysis of [F-18] setoperone PET serotonin(2A) receptor data in schizophrenia | BIOLOGICAL PSYCHIATRY | Verhoeff NPLG, Meyer JH, Kecojevic A, Hussey D, Lewis R, Kapur S | 958017600 | Abstract |
| Imaging extrastriatal dopamine D2 receptor occupancy by endogenous dopamine in healthy humans | European Journal of Pharmacology | Fujita M, Verhoeff NPLG, Varrone A, Zoghbi SS, Baldwin RM, Jatlow PA, Anderson GM, Seibyl JP | 947480400 | Journal Article |
| Dopamine depletion in healthy subjects | Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site | Verhoeff NPLG | 946702800 | Presentation |
| Benzodiazepine receptor imaging in neuropsychiatric disorders | Kunin-Lunenfeld Applied Research Unit Rounds, Baycrest Centre for Geriatric Care | Verhoeff NPLG | 946702800 | Presentation |
| Update on presentations at the American College of Neuropsychopharmacology meeting | Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site | Verhoeff NPLG | 946702800 | Presentation |
| PET studies of serotonin receptors in Schizophrenia: Implications for pathophysiology and therapeutics | XXIInd Meeting of the CINP | Kapur S, Lewis R, Verhoeff NPLG, Jones C, Remington G, Zipursky R | 946702800 | Presentation |
| Kinetic and equilibrium analyses of [123I]epidepride binding to striatal and extrastriatal dopamine D2 receptors | Synapse | Fujita M, Seibyl JP, Verhoeff NP, Ichise M, Baldwin RM, Zoghbi SS, Burger C, Staley JK, Rajeevan N, Charney DS, Innis RB | 945234000 | Journal Article |
| Radiotracer imaging of dopaminergic transmission in neuropsychiatric disorders | Psychopharmacology | Verhoeff NPLG | 944024400 | Journal Article |
| Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D2 receptor binding with [123I]epidepride SPECT | Journal of Nuclear Medicine | Ichise M, Fujita M, Seibyl JP, Verhoeff NP, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB | 941432400 | Journal Article |
| Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D-2 receptor binding with [I-123]epidepride SPECT | JOURNAL OF NUCLEAR MEDICINE | Ichise M, Fujita M, Seibyl JP, Verhoeff NPLG, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB | 941432400 | Presentation |
| [123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia | Psychiatry Research: Neuroimaging | Verhoeff NPLG, Soares JC, D'Souza CD, Gil R, Degen K, Abi-Dargham A,Zoghbi SS, Fujita M, Rajeevan N, Seibyl JP, Krystal JH, van Dyck CH, Charney DS, Innis RB | 939614400 | Journal Article |
| Effects of vigabatrin on the GABA-ergic system as determined by [123I]iomazenil SPECT and GABA MRS | Epilepsia | Verhoeff NPLG, Petroff OAC, Hyder F, Zoghbi SS, Fujita M, Rajeevan N, Rothman DL, Seibyl JP, Mattson RH, Innis RB | 938750400 | Journal Article |
| Multilinear regression, graphical and simplified analyses of striatal and extrastriatal dopamine D-2 receptor binding with [I-123]epidepride SPECT | JOURNAL OF NUCLEAR MEDICINE | Ichise M, Fujita M, Seibyl JP, Verhoeff NP, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB | 928641600 | Abstract |
| Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans | European Journal of Pharmacology | Fujita M, Woods SW, Verhoeff NP, Abi-Dargham A, Baldwin RM, Zoghbi SS, Soares JC, Jatlow PA, Krystal JH, Rajeevan N, Charney DS, Seibyl JP, Innis RB | 920610000 | Journal Article |
| Functional Brain SPECT Imaging: 1999 and Beyond | Nuclear Medicine Annual: 1999 | Tikofsky RS, Ichise M, Seibyl JP, Verhoeff NPLG | 915166800 | Book Chapter |
| Graphical modeling of dopamine D2 receptor binding of 1-123-epidepride to account for labeled lipophilic metabolites | JOURNAL OF NUCLEAR MEDICINE | Ichise M, Fujita M, Seibyl JP, Verhoeff NP, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB | 897192000 | Abstract |
| Benzodiazepine brain SPECT: clinical application | Society of Nuclear Medicine 1998 Handout Book Wednesday and Thursday Courses | Verhoeff NPLG | 883630800 | Book Chapter |
| Benzodiazepine receptor binding and schizophrenia. | American Journal of Psychiatry | Verhoeff NP | 875678400 | Journal Article |
| Neuroreceptor ligand imaging by SPECT in Parkinsonian syndromes | A Textbook of SPECT in Neurology and Psychiatry | Verhoeff NPLG, Booij U, Innis RB, Van Royen EA | 852094800 | Book Chapter |
| Clinical significance of dopamine D2-receptor imaging with 123I-iodobenzamide SPECT in patients with Parkinsonian syndromes | A Textbook of SPECT in Neurology and Psychiatry | Verhoeff NPLG, Speelman JD, Kuiper MA, Van Royen EA, DKapucu O, Boer GJ, Janssen AGM, Wolters ECH | 852094800 | Book Chapter |
| Potential for imaging cerebral amyloid deposits using 123I-labelled serum amyloid P component and SPET. | Nuclear Medicine Communications | Bornebroek M, Verzijlbergen JF, Haan J, Van Scheyen EJ, Verhoeff NP, Pauwels EK, Roos RA | 846824400 | Journal Article |
| Indium-111-DTPA-octreotide uptake measured in normal and abnormal pituitary glands | Journal of Nuclear Medicine | van Royen EA, Verhoeff NP, Meylaerts SA, Miedema AR | 841550400 | Journal Article |
| Dopamine D2 receptor blockade in vivo with the novel antipsychotics risperidone and remoxipride: An 123I-IBZM single photon emission tomography (SPET) study. | Psychopharmacology | Busatto GF, Pilowsky LS, Costa DC, Ell PJ, Verhoeff NP, Kerwin RW | 788936400 | Journal Article |
| Brain SPECT Imaging in Psychiatry | Neuroimaging in Schizophrenia | Verhoeff NPLG | 788936400 | Book Chapter |
| 123I-IBZM SPECT Brain Imaging in Schizophrenia | Brain SPECT Imaging in Psychiatry | Lucey JV, Pilowsky LS, Costa DC, Ell PJ, Verhoeff NPLG, Kerwin RW | 788936400 | Book Chapter |
| Dopamine receptor availability in Tourette's syndrome | Psychiatry Research - Neuroimaging | George MS, Robertson MM, Costa DC, Ell PJ, Trimble MR, Pilowsky L, Verhoeff NP | 786258000 | Journal Article |
| No direct correlation between behaviorally active doses of the dopamine D2 agonist LY 171555 and displacement of [123I]IBZM as measured with SPECT in MPTP monkeys | Synapse | Vermeulen RJ, Drukarch B, Verhoeff NP, Goosen C, Sahadat MC, Wolters EC, van Royen EA, Stoof JC | 770443200 | Journal Article |
| Stereotypy, schizophrenia and dopamine D2 receptor binding in the basal ganglia | Psychological Medicine | Pedro BM, Pilowsky LS, Costa DC, Hemsley DR, Ell PJ, Verhoeff NP, Kerwin RW, Gray NS | 767764800 | Journal Article |
| Striatal dopamine receptor binding in epileptic psychoses | Biological Psychiatry | Ring HA, Trimble MR, Costa DC, Moriarty J, Verhoeff NP, Ell PJ | 763707600 | Journal Article |
| D2 dopamine receptor binding in the basal ganglia of antipsychotic-free schizophrenic patients. An 123I-IBZM single photon emission computerised tomography study. | British Journal of Psychiatry | Pilowsky LS, Costa DC, Ell PJ, Verhoeff NP, Murray RM, Kerwin RW | 757400400 | Journal Article |
| Ligands for neuroreceptor imaging by single photon emission tomography (SPET) or positron emission tomography (PET) | Nuclear Medicine in Clinical Diagnosis and Treatment | Verhoeff NPLG | 757400400 | Book Chapter |
| Estimation of dopamine D2 receptor binding potential in the striatum with iodine-123-IBZM SPECT:Technical and interobserver variability | Journal of Nuclear Medicine | Verhoeff NPLG, Kapucu O, Sokole-Busemann E, Van Royen EA, Janssen AGM | 754722000 | Journal Article |
| Dopamine D2 receptor occupancy in vivo and response to the new antipsychotic risperidone. | British Journal of Psychiatry | Kerwin RW, Busatto GF, Pilowsky LS, Ell PJ, Costa DC, Verhoeff NP, Kerwin RW | 754722000 | Journal Article |
| Dopamine D2-receptor imaging with 123I-iodobenzamide SPECT in migraine patients abusing ergotamine: does ergotamine cross the blood brain barrier? | Cephalalgia | Verhoeff NPLG, Visser WH, Ferrari MD, Saxena PR, Van Royen EA | 749448000 | Journal Article |
| Dosimetry of iodine-123 iodobenzamide in healthy volunteers | European Journal of Nuclear Medicine | Verhoeff NPLG, Busemann Sokole E, Stabin M, Hengst D, Kung HF, Van Royen EA, Janssen AGM | 746856000 | Journal Article |
| Quantification of central benzodiazepine receptor binding potential in the brain with 123I-iomazenil SPECT - technical and interobserver variability | Nuclear Medicine Communications | Verhoeff NPLG, Erbas B, Kapucu O, Busemann Sokole E, Blok H, Van Royen EA | 744177600 | Journal Article |
| Antipsychotic medication, D2 dopamine receptor blockade and clinical response: a 123I IBZM SPET (single photon emission tomography) study | Psychological Medicine | Pilowsky LS, Costa DC, Ell PJ, Murray RM, Verhoeff NPLG, Kerwin RW | 744177600 | Journal Article |
| Imaging of dopamine D2 and somatostatin receptors in vivo using single-photon emission tomography in a patient with a TSH/PRL-producing pituitary macroadenoma | European Journal of Nuclear Medicine | Verhoeff NPLG, Bemelman FJ, Wiersinga WM, Van Royen EA | 738907200 | Journal Article |
| Intracranial dissemination of a macroprolactinoma | Clinical Endocrinology | Assies J, Verhoeff NP, Bosch DA, Hofland LJ | 736228800 | Journal Article |
| Multiple system atrophy and progressive supranuclear palsy. Diminished striatal D2 dopamine receptor activity demonstrated by 123I-IBZM single photon emission computed tomography | Archives of Neurology | Van Royen EA, Verhoeff NPLG, Speelman JD, Wolters EChMJ, Kuiper MA, Janssen AG | 736228800 | Journal Article |
| 123I-SCH 23982 is not suitable for dopamine D1 receptor imaging in vivo in the human brain | Nuclear Medicine Communications | Verhoeff NPLG, Bekier A, Beer HF, Schubiger PA, Fennema P, Van Royen EA | 728542800 | Journal Article |
| Spectral analysis of the EEG and 99mTc-HMPAO SPECT-scan in Alzheimer's disease | Biological Psychiatry | Kwa VIH, Weinstein HC, Posthumus Meyjes FE, Van Royen EA, Bour LJ, Verhoeff NPLG, Ongerboer de Visser BW | 727074000 | Journal Article |
| Neuroreceptor ligand imaging by Single Photon Emission Computerised Tomography (SPECT) | Nuclear Medicine Bulletin | Verhoeff NPLG | 725864400 | Journal Article |
| In vitro and in vivo binding of muscarinic cholinergic receptors with 123I-Iododexetimide in rat brain and heart | Nuclear Medicine Bulletin | Verhoeff NPLG, Bobeldijk M, Van Breukel AIM, Van Vlies B, Maas MAW, Boer GJ,Feenstra MGP, Erdtsieck-Ernste E, DeBruin K, Olivier G, Van Royen EA | 725864400 | Journal Article |
| Dosimetry of iodine-123 iomazenil in humans | European Journal of Nuclear Medicine | Verhoeff NPLG, Busemann Sokole E, Hengst D, Stubbs JB, Van Royen EA | 725864400 | Journal Article |
| Dynamic studies of the binding of 123I-Iomazenil to central benzodiazepine receptors in healthy volunteers | Nuclear Medicine Bulletin | Verhoeff NPLG, Van Royen EA, Overweg J, Limburg M, Stam J, Roolker L, Wiggerts HO, Beer HF | 725864400 | Journal Article |
| Imaging neurotransmission and neuroreceptors - physiological and pharmacological basis | New Trends in Nuclear Neurology and Psychiatry | Verhoeff NPLG | 725864400 | Book Chapter |
| Neuroreceptor ligand imaging by single photon emission computerised tomography (SPECT) | Thesis University of Amsterdam | Verhoeff NPLG | 725864400 | Book Chapter |
| Effect of vigabatrin on striatal dopamine receptors: evidence in humans for interactions of GABA and dopamine systems | Journal of Neurology, Neurosurgery & Psychiatry | Ring HA, Trimble MR, George MS, Costa DC, Verhoeff NPLG, Ell PJ | 715320000 | Journal Article |
| Basics and recommendations for brain SPECT. Task Group "Neurology" of the European Association of Nuclear Medicine. | Nuclear Medicine | Verhoeff NPLG, Büll U, Costa DC, Kirsch G, Lottes G, Moretti JL, Podreka I, Schober O, Van Royen EA | 712641600 | Journal Article |
| Clozapine, single photon emission tomography, and the D2 dopamine receptor blockade hyopothesis of schizophrenia | Lancet | Pilowsky LS, Costa DC, Ell PJ, Murray RM, Verhoeff NPLG, Kerwin RW | 712036800 | Journal Article |
| Nedocromil sodium inhibits the early and late asthmatic response to exercise | European Respiratory Journal | Speelberg B, Verhoeff NP, van den Berg NJ, Oosthoek CH, van Herwaarden CL, Bruijnzeel PL | 702104400 | Journal Article |
| Focus localization in patients with partial epilepsy with 99Tcm-HMPAO SPECT under continuous surface EEG monitoring | Nuclear Medicine Communications | Verhoeff NPLG, Weinstein HC, Aldenkamp AP, Overweg J, Van Royen EA, Verbeeten B Jr | 699426000 | Journal Article |
| Cell biology from a medical perspective. X. Signal transduction | Nederlands tijdschrift voor geneeskunde | Verhoeff NP | 699426000 | Journal Article |
| Parkinson disease, a simple diagnosis? | Nederlands tijdschrift voor geneeskunde | Verhoeff NP, van Royen EA, Speelman JD, Wolters EC, Kuiper MA | 699426000 | Journal Article |
| [The suppressed pill with far-reaching consequences] | Nederlands tijdschrift voor geneeskunde | Verhoeff NP | 696920400 | Journal Article |
| Memory complaints, memory disorders and focus localization in patients with partial epilepsy | Seizure | Verhoeff NPLG, Aldenkamp AP, Overweg J, Van Royen EA, Verbeeten B Jr, Weinstein HC | 694242000 | Journal Article |
| Asthma in children; consensus by pediatric pneumonologists about long-term treatment | Nederlands tijdschrift voor geneeskunde | Verhoeff NP | 694242000 | Journal Article |
| Dopamine D2 receptor availability in patients with Gilles de la Tourette syndrome studied with SPET | Nuclear Medicine in Research and Practice, European Nuclear Medicine Congress, Vienna, September 1-5, 1991 | Costa DC, George MS, Ell PJ, Pilowshy L, Verhoeff NPLG, Robertson MM | 694242000 | Book Chapter |
| In vitro and in vivo binding of muscarinic cholinergic receptors with 123I-Iododexetimide in rat brain and heart | Nuclear Medicine in Research and Practice | Verhoeff NPLG, Bobeldijk M, Van Breukel AIM, Fan Vlies B, Maas MAW, Boer GJ, Feenstra MGP, Erdtsieck-Ernste E, DeBruin K, Olivier G, Van Royen EA | 694242000 | Book Chapter |
| Validity of computerized testing - patient dysfunction and complaints versus measured changes | The Assessment of Cognitive Function in Epilepsy | Aldenkamp AP, Vermeulen J, Alpherts WCJ, Overweg J, Van Parijs JAP, Verhoeff NPLG | 694242000 | Book Chapter |
| Effect of vigabatrin on striatal dopamine receptors | Nuclear Medicine in Research and Practice | Ring HA, Trimble MR, Costa DC, George MS, Verhoeff P, Ell PJ | 694242000 | Book Chapter |
| Dynamic SPECT in two healthy volunteers to determine the optimal time for in vivo D2 dopamine receptor imaging with 123I-IBZM using the rotating gamma camera | Nuclear Medicine Communications | Verhoeff NPLG, Brücke T, Podreka I, Bobeldijk M, Angelberger P, Van Royen EA | 681019200 | Journal Article |
| Evaluation of a multicentre study with Iomazenil- a benzodiazepine receptor ligand | Nuclear Medicine Communications | Schubiger PA, Hasler PH, Beer-Wohlfahrt H, Bejier A, Oettli R, Cordes M, Ferstl F, Deisenhammer E, De Roo M, Moser E, Nitzsche E, Podreka I, Riccabona G, Bangerl I, Schober O, Bartenstein P, Van Rijk P, Van Isselt JW, Van Royen EA, Verhoeff NPLG, Haldemann R, Von Schultess GK | 678340800 | Journal Article |
| Dopamine D2-receptor imaging with dynamic I-123 IBZM SPET in patients with schizophrenia or HIV encephalopathy | Nuclear Medicine : The State Of The Art Of Nuclear Medicine In European | Verhoeff NPLG, Costa DC, Ell PJ, Toone B, Palasidou E, Cullum ID, Bobeldij M, Miller R, Syed GMS, Barrett JJ, Soricelli A, Van Royen EA | 662706000 | Book Chapter |
| Hersenfunctieonderzoek met behulp van isotopen | Medical Technology | Verhoeff NPLG | 662706000 | Journal Article |
| Pharmacological implications for neuroreceptor imaging | European Journal of Nuclear Medicine | Verhoeff NPLG | 662706000 | Journal Article |
| Benzodiazepine receptor density in human brain measured in vivo with I-123 iomazenil SPECT | Nuclear Medicine : The State Of The Art Of Nuclear Medicine In European | Verhoeff NPLG, Van Royen EA, Ell PJ, Costa DC, Hasler PH, Schubiger PA | 662706000 | Book Chapter |
| In vitro and in vivo D2-dopamine receptor binding with [123I]S(-)iodobenzamide ([123I]IBZM) in rat and human brain | Nuclear Medicine and Biology - Part B: International Journal of Radiation Applications and Instrumentation | Verhoeff NP, Bobeldijk M, Feenstra MG, Boer GJ, Maas MA, Erdtsieck-Ernste E, de Bruin K, van Royen EA | 662706000 | Journal Article |
| A simple and high-yield synthesis of (S)-BZM, (R)-BZM and (S)-IBZM for the preparation of (S)-123I-IBZM | Journal of Labelled Compounds and Radiopharmaceuticals | Bobeldijk M, Verhoeff NPLG, Vekemans JAJM, Buck HM, Van Doremalen PAPM, Van Hoof JJ, Janssen AGM | 657435600 | Journal Article |
| Real and pseudo late asthmatic reactions after submaximal exercise challenge in patients with bronchial asthma. A new definition for late asthmatic responses after exercise challenge | Chest | Verhoeff NPLG, Speelberg B, Van den Berg NJ, Oosthoek CHA, Stijnen T | 657435600 | Journal Article |
| In vivo characterisation of 3-iodo-6-methoxybenzamide 123I in humans | European Journal of Nuclear Medicine | Costa DC, Verhoeff NP, Cullum ID, Ell PJ, Syed GM, Barrett J, Palazidou E, Toone B, Van Royen E, Bobeldijk M | 646804800 | Journal Article |
| A comparison of Tl-201-DDC and Tc-99m-HMPAO SPECT in patients with ischemic stroke or dementia | Nuclear Medicine Bulletin | Verhoeff NPLG, Van Kanten J, Van der Zant FM, Van Royen EA, Weinstein H, Limburg M | 631170000 | Journal Article |
| A comparison of Tl-201-DDC and Tc-99m-HMPAO SPECT in patients with ischemic stroke or dementia | The State of the Art of Nuclear Medicine in Europe | Verhoeff NPLG, Van Kanten J, Fan der Zant FM, Van Royen EA, Weinstein H, Limburg M | 631170000 | Book Chapter |
| Benzodiazepine receptor density in human brain measured in vivo with 123-Iomazenil SPECT | The State of the Art of Nuclear Medicine in Europe | Verhoeff NPLG, Van Royen EA, Ell PJ, Costa C, Hasler PH, Schubiger PA | 631170000 | Book Chapter |
| Immediate and late asthmatic responses induced by exercise in patients with reversible airflow limitation | European Respiratory Journal | Speelberg B, van den Berg NJ, Oosthoek CH, Verhoeff NP, van den Brink WT | 609998400 | Journal Article |
| The prevalence of the early and late asthmatic reaction after exercise in patients with intrinsic and extrinsic asthma | Agents and Actions Supplement | Speelberg B, Verhoeff NP, van den Brink WT | 599634000 | Journal Article |
| Benzodiazepine receptor density in human cerebral cortex and cerebellum measured in vivo with 123I-Iomazenil SPECT | Iomazenil and Other Brain Receptor Tracers for SPECT, Proceedings of the 6th Bottstein Colloquim, Wurenlingen Villigen, Switzerland | Verhoeff NPLG, Van Royen EA, Overweg J, Limburg M, Hijdra A, Linszen D | 599634000 | Book Chapter |
Education
- 2003: Diplomate of the American Board of Psychiatry and Neurology, Inc., Member Board of the American Board of Medical Specialties, (# 53130 )
- 2003: Examination Part II, American Board of Psychiatry and Neurology
- 2002: Certificate of Registration for Independent, Practice from the College of Physicians and Surgeons of Ontario (# 74459)
- 2001: Licentiate of the Medical Council of Canada, Canadian Medical Register (# 91136 )
- 2001: Qualifying Examination Part II , Medical Council of Canada (# 9980517)
Academic Appointments
- 2005–Present: Associate Professor of Psychiatry, Department of Psychiatry, Geriatric Program, University of Toronto, Toronto, Ontario, Canada (# 1016849 )
- 2003–Present: Staff Psychiatrist, Brain Health Centre, Behavioural Neurology Memory Disorders Clinic, and Geriatric Psychiatry Community Service, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
- 2001–Present: Neuropsychiatry Clinician-Scientist and Staff Psychiatrist, Kunin-Lunenfeld Applied Research Unit, Geriatric Psychiatry Community Service, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
Reviewership
Consulting
- 1992: European Journal of Nuclear Medicine
- 1999: Psychopharmacology
- 2001: American Journal of Psychiatry
- 2001: Journal of Neurochemistry
- 2000–2001: Journal of Neuropsychiatry and Clinical Neurosciences
- 2003: Journal of Neuropsychiatry and Clinical Neurosciences
- 2001–2003: Journal of Psychiatry and Neuroscience
- 2002: NeuroImage
- 2002: Archives of General Psychiatry
- 2003–2010: American Journal of Geriatric Psychiatry
- 2005: American Journal of Geriatric Psychiatry
- 2000: Neuropsychopharmacology
- 2000–2003: Psychiatry Research: Neuroimaging
- 2003: Biological Psychiatry
- 2004: Brain
Committee
- 2010: Thesis (Dr. Christina Siwak, PhD (2002). Thesis: Age-related changes in non-cognitive behaviours in a canine model of aging and dementia and therapeutic evaluation of adrafinil and modafinil. )
- 2010: Thesis (Ms. Jennifer Glass, MSc (2002-present). Thesis: Clinical effects of benzodiazepines in the elderly. )
- 2010: Thesis (Ms. Pearl Behl, MSc (2004-present). Thesis: Longitudinal effects of cholinergic therapy on Alzheimer’s disease (AD)- a neurobehavioral, structural and functional imaging study. )
- 2010: Thesis (Matthew Parrott (2005-present). Thesis: Postprandial memory response in MCI/MCI-like subjects.)
- 2010: European Association of Nuclear Medicine Neuroimaging Committee (Professional Committee )
- 2004: National Institutes of Health – National Institute of Aging Review Committee member (Professional Committee: "reverse" site visit from July 29-30, 2004, in Bethesda, MD, USA, to review a Program Project Grant application by the University of Pittsburgh School of Medicine on behalf of Dr. Steven DeKosky, MD, PhD: "In Vivo PIB PET Amyloid Imaging: Normals, MCI & Dementia." )
- 2004: National Institutes of Health – National Institute of Aging Review Committee member (Professional Committee: "reverse" site visit from November 2-3, 2004, in Bethesda, MD, USA, to review a Program Project Grant application by the University College of Los Angeles on behalf of Dr. Gary Small, MD: "Amyloid Imaging in Aging.")
Membership
- 2010: American Psychiatric Association (Member # 80011 )
- 2010: Canadian Medical Association (Member # 120718)
- 2010: Ontario Medical Association (Member # 079-4834)
- 2010: Canadian Medical Protective Association (Member # 1001169)
- 2010: Scientific Review Board of the Institute for the Study of Aging
Distinctions and Awards
- 2005: Outstanding Service Award, Baycrest Centre for Geriatric Care, Employee Recognition and Rewards Committee Implementation Team at Baycrest Centre for clinical services provided at the Brain Health Centre Memory Disorders Clinic, April 29, 2005 , 75.00
- 2004: Alzheimer’s Association Travel Fellowship 2004, 9th International Conference on Alzheimer's Disease and Related Disorders, USD. July 17-22, 2004, Philadelphia, Pennsylvania, USA, 645
- 2003: International Junior Investigator Award 2003, International College of Geriatric Psychoneuropharmacology (ICGP) , USD. Provided at the International College of Geriatric Psychoneuropharmacology 3rd Annual Meeting, December 12-14, 2003 San Juan, Puerto Rico. , 2,000
- 1999: American Psychiatric Association/Lilly Resident Research Award 1998-1999, American Psychiatric Association annual meeting, USD. Washington, DC , 1,500
- 1998: American College of Neuropsychopharmacology (ACNP) Travel Award 1998, Bristol-Myers-Squibb and the American College of Neuropsychopharmacology 37th annual meeting, USD. Las Croabas, Puerto Rico , 2,000
- 1990: Mallinckrodt-Award 1990 - best presentation from the Benelux, Congress of the European Association of Nuclear Medicine in Amsterdam, Hfl (Dutch guilders), 2,500
Research Projects
External
-
2004–2006:
β-amyloid PET imaging in Alzheimer’s disease
Sponsors: Alzheimer’s Association New Investigator Research Grant, 100,000 (USD)
-
2003–2006:
Beta amyloid PET imaging in vivo for early detection of Alzheimer's disease
Sponsors: Scottish Rite Charitable Foundation of Canada’s Major Research Grant, 104,983 (CAD)
-
2002–2004:
Imaging amyloid plaques with PET in patients with Alzheimer’s disease
Sponsors: Alzheimer Society of Canada Young Investigator Grant, 50,000 (CAD)
more EducationDecember 2000:
Fellow of the Royal College of Physicians and Surgeons of Canada (# 556363)
November 2000:
Passed Royal College of Physicians and Surgeons Psychiatry Examination Part II(# 556363)
September 2000:
Passed Royal College of Physicians and Surgeons Psychiatry Examination Part I(# 556363)
May 2000:
Passed Medical Council of Canada Qualifying Examination Part I (# 9980517)
January 2000:
Certificate of Registration for Postgraduate Education from the College of Physicians and Surgeons of Ontario (# 74459)
October 1999:
Physician Licensure in The Netherlands, European Union (# 29024521601)
September 1999:
Passed Medical Council of Canada Evaluating Examination (# 9980517)
November 1998:
Passed American Board of Psychiatry and Neurology Examination Part I
November 1996:
Physician Licensure in Connecticut, United States of America (# 035708)
February 1996:
Passed United States Medical Licensure Examination Steps 1, 2 and 3 (# 0-505-330-1)
April 1993:
PhD Thesis Neurosciences Amsterdam on theme: Neuroreceptor Imaging with SPECT',
University of Amsterdam (cum laude)
October 1988:
MD by Medical Qualifying Examination (cum laude), Erasmus University Rotterdam
September 1986:
Examination for the 'drs.' degree in Medicine, Erasmus University Rotterdam
July 1983:
Propaedeutics in Medicine (cum laude), Erasmus University Rotterdam
Fellow of the Royal College of Physicians and Surgeons of Canada (# 556363)
November 2000:
Passed Royal College of Physicians and Surgeons Psychiatry Examination Part II(# 556363)
September 2000:
Passed Royal College of Physicians and Surgeons Psychiatry Examination Part I(# 556363)
May 2000:
Passed Medical Council of Canada Qualifying Examination Part I (# 9980517)
January 2000:
Certificate of Registration for Postgraduate Education from the College of Physicians and Surgeons of Ontario (# 74459)
October 1999:
Physician Licensure in The Netherlands, European Union (# 29024521601)
September 1999:
Passed Medical Council of Canada Evaluating Examination (# 9980517)
November 1998:
Passed American Board of Psychiatry and Neurology Examination Part I
November 1996:
Physician Licensure in Connecticut, United States of America (# 035708)
February 1996:
Passed United States Medical Licensure Examination Steps 1, 2 and 3 (# 0-505-330-1)
April 1993:
PhD Thesis Neurosciences Amsterdam on theme: Neuroreceptor Imaging with SPECT',
University of Amsterdam (cum laude)
October 1988:
MD by Medical Qualifying Examination (cum laude), Erasmus University Rotterdam
September 1986:
Examination for the 'drs.' degree in Medicine, Erasmus University Rotterdam
July 1983:
Propaedeutics in Medicine (cum laude), Erasmus University Rotterdam
more Academic AppointmentsApril 2001-April 2005
Assistant Professor of Psychiatry (# 1016849)
Department of Psychiatry, Geriatric Program,
University of Toronto, Toronto, Ontario, Canada
August 1999-July 2001
Clinical Research Fellow
Schizophrenia/PET Centre, Clarke Division,
Centre for Addiction and Mental Health,
Toronto, Ontario, Canada
July 1998-July 1999
Advanced Resident and Fellow in Addiction Psychiatry,
Department of Psychiatry,
Yale University School of Medicine, New Haven,
Connecticut, United States of America
July 1994-June 1998
Resident, Department of Psychiatry,
(Neuroscience Research Training Program)
Yale University School of Medicine, New Haven,
Connecticut, United States of America
March 1994-June 1994
Resident, Department of Psychiatry,
Cluster of Patients with Schizophrenia,
Academic Hospital Groningen, Netherlands
March 1993-February 1994
Served as MD and First-Lieutenant,
Dutch Landforces at the Central Section for Individual Psychosocial Aid.
Worked as clinical psychologist.
Assistant Professor of Psychiatry (# 1016849)
Department of Psychiatry, Geriatric Program,
University of Toronto, Toronto, Ontario, Canada
August 1999-July 2001
Clinical Research Fellow
Schizophrenia/PET Centre, Clarke Division,
Centre for Addiction and Mental Health,
Toronto, Ontario, Canada
July 1998-July 1999
Advanced Resident and Fellow in Addiction Psychiatry,
Department of Psychiatry,
Yale University School of Medicine, New Haven,
Connecticut, United States of America
July 1994-June 1998
Resident, Department of Psychiatry,
(Neuroscience Research Training Program)
Yale University School of Medicine, New Haven,
Connecticut, United States of America
March 1994-June 1994
Resident, Department of Psychiatry,
Cluster of Patients with Schizophrenia,
Academic Hospital Groningen, Netherlands
March 1993-February 1994
Served as MD and First-Lieutenant,
Dutch Landforces at the Central Section for Individual Psychosocial Aid.
Worked as clinical psychologist.
more Teaching
1.
Organized from September 1999 until July 2000 the weekly Schizophrenia
Research Seminars of the Schizophrenia & Continuing Care Division
at the Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
2. Organized from September 2005 until the present the weekly Grand Rounds at the Baycrest Department of Geriatric Psychiatry.
3. Organized as Course Director the KLARU-Baycrest-CAMH-UofT Division of Geriatric Psychiatry Conference “Behavioural Problems in Dementia - Late-Life Depression: Connecting Research and Clinical Care”, which was held on October 20, 2006.
4. Presenting regularly at the following rounds at Baycrest Centre for Geriatric Care (for specific presentations, see Oral Conference Presentations list below):
a. Baycrest Centre Grand Rounds
b. Evidence Based Clinical Practice Seminars
c. Geriatric Psychiatry Seminar Series
d. Grand Rounds at the Baycrest Department of Geriatric Psychiatry
e. Kunin-Lunenfeld Applied Research Unit Rounds
f. Rotman Research Institute Rounds
g. Rounds at the Department of Behavioural Neurology.
5. Supervisor of psychiatry resident Dr. Eileen Sloan, MD, PhD, from March 20, 2003, until June 30, 2003.
6. Supervisor of geriatric medicine fellow Dr. Tricia Woo, MD, from July 18, 2003, until July 31, 2003.
7. Supervisor of psychiatry resident Dr. Treena Wilkie, MD, from July 8, 2003, until December 31, 2003.
8. Supervisor of clinical research fellow Dr. Shinichiro Takeshita, MD, PhD, and Neurosurgeon in Japan, from October 17, 2003, until October 16, 2005.
9. Supervisor of psychiatry resident Dr. Michele Korostil, MD, from January 5, 2004, until June 30, 2004.
10. Supervisor of psychiatry resident Dr. Jinous Hamidi, MD, from July 1, 2004, until December 31, 2004.
11. Supervisor of psychiatry resident Dr. Virginia Wesson, MD, from January 1, 2005, until June 30, 2005.
12. Supervisor of clinical research fellow Dr. Kie Honjo, MD, PhD, and Neurologist in Japan, from April 1, 2005, until September 30, 2005.
13. Supervisor of the following fellows, residents and medical students at the Baycrest Behavioural Neurology Memory Disorders Clinic:
a. Dr. Philip Lee, MD, FRCPC (behavioural neurology fellow) from December 1, 2003, until February 15, 2004
b. Dr. Yakir Kaufman, MD (behavioural neurology fellow) from December 1, 2003, until June 30, 2004
c. Dr. Laura McCabe, MD (PGY-5 psychiatry resident) from December 1, 2003, until December 31, 2003
d. Dr. Esther Bui, MD (neurology resident) from January 1-31, 2004
e. Dr. Tricia Woo, MD (geriatric medicine fellow) from February 1-28, 2004
f. Dr. Andrew Lim, MD (neurology resident) from July 1, 2004, until August 2, 2004
g. Dr. Yael Friedman, MD (neurology resident) from August 3, 2004, until August 28, 2004
h. Dr. Khalid Hassan, MD(neurology resident) from November 1, 2004, until November 28, 2004
i. Dr. Elizabeth Layne, MD (PGY-5 psychiatry resident) from November 29, 2004, until January 2, 2005
j. Dr. Mihaela Nicula, MD (geriatric medicine fellow) from January 3, 2005, until January 30, 2005.
k. Dr. Nahathai Wongpakaran, MD (geriatric psychiatry fellow from Thailand) from December 2, 2004, until May 31, 2005 (observer status only).
l. Dr. Ling Yap, MD (geriatric psychiatry fellow from Singapore) on April 21, 2005 (observer status only).
m. Dr. Daniel Martinez, MD (geriatric medicine fellow from Argentina) on May 6, 2005 (observer status only).
n. Dr. Marcelo Blacutt, MD (geriatric medicine fellow from Chile) from June 9, 2005, until June 30, 2005.
o. Dr. Vincenzo Santo Basile, MD (neurology resident) from September 1, 2005, until October 2, 2005.
p. Dr. Thirumgalal Yogaparan, MD (geriatric medicine fellow from Sri Lanka and the USA) from November 1, 2005, until December 31, 2005.
q. Dr. Diyana Docheva, MD (geriatric medicine fellow from Bulgaria) on April 11, 2006.
r. Dr. Fabricio Joao Pio, MD, (neurology fellow from Brazil) from April 25, 2006, until May 31, 2006.
s. Dr. Jiwon Oh, MD (neurology resident) from September 12, 2006, until September 26, 2006.
t. Dr. Yael Perez, MD (neurology resident) from October 10, 2006, until October 27, 2006.
u. Dr. Suvendrini Lena, MD (neurology resident) from November 20, 2006, until November 22, 2006.
v. Dr. Phil Gerretsen, MD (4th year medical student from McMaster University, Hamilton, Ontario) from January 9, 2007, until January 19, 2007.
w. Dr. Maria Luisa Pio-Ferreira (4th year medical student from Brazil) on January 16, 2007.
2. Organized from September 2005 until the present the weekly Grand Rounds at the Baycrest Department of Geriatric Psychiatry.
3. Organized as Course Director the KLARU-Baycrest-CAMH-UofT Division of Geriatric Psychiatry Conference “Behavioural Problems in Dementia - Late-Life Depression: Connecting Research and Clinical Care”, which was held on October 20, 2006.
4. Presenting regularly at the following rounds at Baycrest Centre for Geriatric Care (for specific presentations, see Oral Conference Presentations list below):
a. Baycrest Centre Grand Rounds
b. Evidence Based Clinical Practice Seminars
c. Geriatric Psychiatry Seminar Series
d. Grand Rounds at the Baycrest Department of Geriatric Psychiatry
e. Kunin-Lunenfeld Applied Research Unit Rounds
f. Rotman Research Institute Rounds
g. Rounds at the Department of Behavioural Neurology.
5. Supervisor of psychiatry resident Dr. Eileen Sloan, MD, PhD, from March 20, 2003, until June 30, 2003.
6. Supervisor of geriatric medicine fellow Dr. Tricia Woo, MD, from July 18, 2003, until July 31, 2003.
7. Supervisor of psychiatry resident Dr. Treena Wilkie, MD, from July 8, 2003, until December 31, 2003.
8. Supervisor of clinical research fellow Dr. Shinichiro Takeshita, MD, PhD, and Neurosurgeon in Japan, from October 17, 2003, until October 16, 2005.
9. Supervisor of psychiatry resident Dr. Michele Korostil, MD, from January 5, 2004, until June 30, 2004.
10. Supervisor of psychiatry resident Dr. Jinous Hamidi, MD, from July 1, 2004, until December 31, 2004.
11. Supervisor of psychiatry resident Dr. Virginia Wesson, MD, from January 1, 2005, until June 30, 2005.
12. Supervisor of clinical research fellow Dr. Kie Honjo, MD, PhD, and Neurologist in Japan, from April 1, 2005, until September 30, 2005.
13. Supervisor of the following fellows, residents and medical students at the Baycrest Behavioural Neurology Memory Disorders Clinic:
a. Dr. Philip Lee, MD, FRCPC (behavioural neurology fellow) from December 1, 2003, until February 15, 2004
b. Dr. Yakir Kaufman, MD (behavioural neurology fellow) from December 1, 2003, until June 30, 2004
c. Dr. Laura McCabe, MD (PGY-5 psychiatry resident) from December 1, 2003, until December 31, 2003
d. Dr. Esther Bui, MD (neurology resident) from January 1-31, 2004
e. Dr. Tricia Woo, MD (geriatric medicine fellow) from February 1-28, 2004
f. Dr. Andrew Lim, MD (neurology resident) from July 1, 2004, until August 2, 2004
g. Dr. Yael Friedman, MD (neurology resident) from August 3, 2004, until August 28, 2004
h. Dr. Khalid Hassan, MD(neurology resident) from November 1, 2004, until November 28, 2004
i. Dr. Elizabeth Layne, MD (PGY-5 psychiatry resident) from November 29, 2004, until January 2, 2005
j. Dr. Mihaela Nicula, MD (geriatric medicine fellow) from January 3, 2005, until January 30, 2005.
k. Dr. Nahathai Wongpakaran, MD (geriatric psychiatry fellow from Thailand) from December 2, 2004, until May 31, 2005 (observer status only).
l. Dr. Ling Yap, MD (geriatric psychiatry fellow from Singapore) on April 21, 2005 (observer status only).
m. Dr. Daniel Martinez, MD (geriatric medicine fellow from Argentina) on May 6, 2005 (observer status only).
n. Dr. Marcelo Blacutt, MD (geriatric medicine fellow from Chile) from June 9, 2005, until June 30, 2005.
o. Dr. Vincenzo Santo Basile, MD (neurology resident) from September 1, 2005, until October 2, 2005.
p. Dr. Thirumgalal Yogaparan, MD (geriatric medicine fellow from Sri Lanka and the USA) from November 1, 2005, until December 31, 2005.
q. Dr. Diyana Docheva, MD (geriatric medicine fellow from Bulgaria) on April 11, 2006.
r. Dr. Fabricio Joao Pio, MD, (neurology fellow from Brazil) from April 25, 2006, until May 31, 2006.
s. Dr. Jiwon Oh, MD (neurology resident) from September 12, 2006, until September 26, 2006.
t. Dr. Yael Perez, MD (neurology resident) from October 10, 2006, until October 27, 2006.
u. Dr. Suvendrini Lena, MD (neurology resident) from November 20, 2006, until November 22, 2006.
v. Dr. Phil Gerretsen, MD (4th year medical student from McMaster University, Hamilton, Ontario) from January 9, 2007, until January 19, 2007.
w. Dr. Maria Luisa Pio-Ferreira (4th year medical student from Brazil) on January 16, 2007.
more Research Projects4.
University of Toronto Dean’s Fund New Staff Grant: From July 1, 2002 –
June 30, 2007. Title: Imaging amyloid plaques with PET in a beagle dog
model for Alzheimer’s disease. Total amount: $ 10,000 (Canadian)
5. National Alliance for Schizophrenia and Affective Disorders Young Investigator Award: from July 1, 1999 – June 30, 2001. Title: Imaging striatal synaptic dopamine levels and dopamine D2 receptor binding potential in schizophrenic patients and in control subjects using [11C]raclopride PET. Total amount: $ 60,000 (US)
6. Ontario Mental Health Foundation Postdoctoral Fellowship: from July 1, 1999 – June 30, 2001. Title: Imaging striatal synaptic dopamine levels and dopamine D2 receptor binding potential in schizophrenic patients and in control subjects using [11C]raclopride PET. Total amount: $ 65,300 (Canadian)
Grant support (Collaborator):
5. National Alliance for Schizophrenia and Affective Disorders Young Investigator Award: from July 1, 1999 – June 30, 2001. Title: Imaging striatal synaptic dopamine levels and dopamine D2 receptor binding potential in schizophrenic patients and in control subjects using [11C]raclopride PET. Total amount: $ 60,000 (US)
6. Ontario Mental Health Foundation Postdoctoral Fellowship: from July 1, 1999 – June 30, 2001. Title: Imaging striatal synaptic dopamine levels and dopamine D2 receptor binding potential in schizophrenic patients and in control subjects using [11C]raclopride PET. Total amount: $ 65,300 (Canadian)
Grant support (Collaborator):
1.
Alzheimer Society of Canada: from September 1, 2006 – August 31, 2008.
Principal investigator: Dr. Angela Troyer, PhD, CPsych. Title: Amnestic
Mild Cognitive Impairment: Cognitive and Neural Mechanisms. Total
amount: $149,977 (Canadian).
2. Orphan Medical Inc.: from
January 1, 2004 - December 31, 2006. Principal Investigator: Dr. Morris
Freedman, MD, FRCPC. Title: Gammahydroxybutyrate in Alzheimer's
Disease: Cognitive, Behavioural and EEG Effects. Total amount: $822,765
(Canadian)
3. CIHR Randomized Controlled Clinical Trials Unit:
from October 1, 2002, until September 30, 2005. Principal Investigator:
Dr. Robert van Reekum, MD, FRCPC. Title: A Randomized Controlled Trial
of the effects of donepezil on cognitive, behavioural, and functional
outcome in traumatic brain injury. Total amount: $ $334,326 (Canadian)
Curriculum Vitae
Contact
Kunin-Lunenfeld Applied Research UnitBaycrest
3560 Bathurst Street, 762
Toronto, Ontario
Canada M6A 2E1 Phone: 416-785-2500-x2167 Email: pverhoeff
klaru-baycrest.on.ca Fax: 416-785-4230
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