Paul Verhoeff

Paul Verhoeff, MD, PhD, FRCPC

Associate Professor of Psychiatry Department of Psychiatry, Geriatric Program, University of Toronto

Staff Psychiatrist Brain Health Centre, Behavioural Neurology Memory Disorders Clinic, and Geriatric Psychiatry Community Service, Baycrest Centre for Geriatric Care

Neuropsychiatry Clinician-Scientist and Staff Psychiatrist Kunin-Lunenfeld Applied Research Unit, Geriatric Psychiatry Community Service, Baycrest Centre for Geriatric Care

Research Focus

Most of my research activities have centered around neuroreceptor imaging in vivo with positron emission tomography (PET) or single-photon computerized tomography (SPECT) in patients with neuropsychiatric disorders and in healthy control subjects. The research projects are listed according to the neurochemical transmission systems that have been studied, with further clarification as to which patient groups were involved during which period:

Publications

Title Source (Journal/Book/Conference) Authors/Presenters Published On Type
Negative emotional verbal memory biases in mild cognitive impairment and late-onset depression American Journal of Geriatric Psychiatry Mah L, Anderson ND, Verhoeff NPLG, Pollock BG 1494388800 Journal Article
Fluorodeoxyglucose positron emission tomography in semantic dementia after 6 months of memantine: an open-label pilot study. International journal of geriatric psychiatry Chow TW, Fam D, Graff-Guerrero A, Verhoeff NP, Tang-Wai DF, Masellis M, Black SE, Wilson AA, Houle S, Pollock BG 1357016400 Journal Article
An [11C]SB-13 PET study correlating neuropsychiatric symptoms in Alzheimer’s disease with regional beta-amyloid burden Psychiatry Research: Neuroimaging Kaye ED, Honjo K, Petrovic-Poljak A, Reekum R, Streiner DL, Wilson AA, Black SE, Freedman M, Rusjan P, Houle S, Chow TW, Verhoeff NPLG 1325307600 Journal Article
Amyloid imaging with [11C]SB-13 PET: a test-retest reliability study 36th Annual Harvery Stancer Research Day Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black S 1303963200 Presentation
Amyloid Imaging with [11C]SB-13 PET: A Test-Retest Reliability Study Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black S 1278734400 Presentation
Amyloid imaging with [11C]SB-13 PET: A test-retest reliability study ALZHEIMER'S & DEMENTIA Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black SE 1278734400 Abstract
Correlating neuropsychiatric symptoms with cerebral beta-amyloid load in mild Alzheimer's disease using [11C]SB-13 PET Kaye ED, Honjo K, Petrovic-Poljak A, van Reekum R, Streiner DL, Wilson A, Black SE, Freedman M, Rusjan P, Houle S, Verhoeff NPLG 1276747200 Presentation
Frontotemporal dementia and pharmacologic interventions Journal of Neuropsychiatry and Clinical Neurosciences Kaye ED, Petrovic-Poljak A, Verhoeff NP, Freedman M 1265000400 Journal Article
Commentary on the letter for Alzheimer’s disease and infection: Do infectious agents contribute to progression of Alzheimer’s disease? Alzheimer’s & Dementia Honjo K, Van Reekum R, Verhoeff NPLG 1262322000 Journal Article
Correlating neuropsychiatric symptoms with regional Beta-Amyloid load in the Alzheimer’s Disease brain using [11C]SB-13 PET Kaye E, Honjo K, Petrovic-Poljak A, van Reekum R, Streiner D, Wilson A, Black S, Freedman M, Rusjan P, Houle S, Verhoeff P 1258088400 Presentation
Does Beta-Amyloid correlate with neuropsychiatric symptoms in mild Alzheimer’s Disease? Kaye E, Honjo K, Petrovic-Poljak A, van Reekum R, Streiner D, Wilson A, Black S, Freedman M, Rusjan P, Houle S, Verhoeff P 1258088400 Presentation
Functional outcome in delusional Alzheimer Disease patients - A systematic review Dementia and Geriatric Cognitive Disorders Fischer CE, Verhoeff NPLG, Churchill K, Schweizer TA 1254974400 Journal Article
Pre-and post-memantine FDG-PET imaging in frontotemporal dementia 5th Canadian Conference on Dementia Chow TW, Binns MA, Freedman M, Pollock BG, Verhoeff NP, Graff-Guerrero A 1254369600 Presentation
Amyloid Imaging with [11C]SB-13 PET: A Test-Retest Reliability Study CANADIAN JOURNAL OF GERIATRICS Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black S 1254369600 Abstract
Pre- and post-memantine FDG-PET imaging in frontotemporal dementia 5th Canadian Conference on Dementia Chow TW, Binns MA, Freedman M, Pollock B, Verhoeff NPLG, Graff-Guerrero A 1254369600 Presentation
Alzheimer's disease and infection: do infectious agents contribute to progression of Alzheimer's disease? Alzheimer’s & Dementia Honjo K, Van Reekum R, Verhoeff NPLG 1246420800 Journal Article
Amyloid imaging with [11C]SB-13 PET: a test-retest reliability study 35th Annual Harvery Stancer Research Day Verhoeff NPLG, Honjo K, Kaye ED, Petrovic-Poljak A, Wilson AA, Rusjan P, Houle S, van Reekum R, Freedman M, Black S 1245902400 Presentation
Correlating neuropsychiatric symptoms with regional beta-amyloid load in the Alzheimer’s disease brain using [11C]SB-13 PET UNIVERSITY OF TORONTO DEPARTMENT OF PSYCHIATRY Kaye ED, Honjo K, Petrovic-Poljak A, Van Reekum R, Streiner D, Wilson AA, Black SE, Freedman M, Rusjan P, Houle S, Verhoeff NPLG 1245902400 Abstract
Correlating neuropsychiatric symptoms with regional beta-amyloid load in the Alzheimer’s disease brain using [11C]SB-13 PET CANADIAN JOURNAL OF GERIATRICS Kaye ED, Honjo K, Petrovic-Poljak A, Van Reekum R, Streiner D, Wilson AA, Black SE, Freedman M, Rusjan P, Houle S, Verhoeff NPLG 1240632000 Abstract
Pre- and post-memantine FDG-PET imaging in frontotemporal dementia AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Chow T, Binns M, Dombrower H, Freedman M, Verhoeff P, Pollock BG 1236229200 Abstract
Pre- and post-memantine FDG-PET imaging in frontotemporal dementia. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Chow TW, Binns MA, Freedman M, Pollock B, Verhoeff NPLG, Graff-Guerrero A 1236229200 Abstract
A positron emission tomography study of 5-hydroxytryptamine-1A receptors in Alzheimer disease American Journal of Geriatric Psychiatry Lanctot KL, Hussey DF, Herrmann N, Black SE, Rusjan PM, Wilson AA, Houle S, Kozloff N, Verhoeff NP, Kapur S 1191211200 Journal Article
Comparison of manual and semi-automated delineation of regions of interest for radioligand PET imaging analysis BMC Nuclear Medicine Chow TW, Takeshita S, Honjo K, Pataky CE, St Jacques PL, Kusano ML, Caldwell CB, Ramirez J, Black S, Verhoeff NPLG 1167627600 Journal Article
PET and SPECT imaging in psychiatric disorders Canadian Journal of Psychiatry Zipursky RB, Meyer JH, Verhoeff NP 1167627600 Journal Article
Frontal-subcortical circuits and a rationale for neuroreceptor quantification in FTD NEUROPSYCHOPHARMACOLOGY Chow T, Rusjan P, Meyer J, Verhoeff NP, Pollock BG, Smith G 1165122000 Abstract
Elevated putamen D2 receptor binding potential in major depression with motor retardation: An [11C]raclopride Positron Emission Tomography study American Journal of Psychiatry Meyer JH, McNeely HE, Sagrati S, Boovariwala A, Martin K, Verhoeff NPLG, Wilson AA, Houle S 1157083200 Journal Article
Left orbitofrontal atrophy correlates with disinhibition and apathy in frontotemporal degeneration ALZHEIMER’S & DEMENTIA Chow TW, Binns MA, Freedman M, Stuss DT, Ramirez J, Verhoeff NPLG, Black SE 1153022400 Abstract
Alzheimer's disease and cerebrovascular disease - links with amyloid beta protein Kunin-Lunenfeld Applied Research Unit Rounds Honjo K, Verhoeff NPLG 1136091600 Presentation
What relevant aspects of the beta-amyloid cascade do we image with [11C]SB-13 PET? Neuroscience Rounds at at Sunnybrook and Women's College Health Sciences Centre Verhoeff NPLG, Honjo K 1136091600 Presentation
Nuclear medicine: how can it help to optimize treatment for schizophrenia? Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1136091600 Presentation
Agitation and psychotic disorders in the elderly Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1136091600 Presentation
Alcohol and substance abuse in the elderly Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1136091600 Presentation
Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade PET Centre Seminars at the Centre for Addiction and Mental Health, Clarke Site Verhoeff NPLG 1136091600 Presentation
Nuclear medicine: how can it help to optimize treatment for schizophrenia? Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG 1136091600 Presentation
Alzheimer's disease and cerebrovascular disease - links with amyloid beta protein Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Honjo K, Verhoeff NPLG 1136091600 Presentation
Alzheimer disease (AD) and cerebrovascular disease (CVD) - links with amyloid beta protein Grand Rounds at the Department of Geriatric Psychiatry Honjo K, Verhoeff NPLG 1136091600 Presentation
Effect of subthalamic stimulation on mood state in Parkinson's disease: evaluation of previous facts and problems Neurosurgical Review Takeshita S, Kurisu K, Trop L, Arita K, Akimitsu T, Verhoeff NPLG 1120190400 Journal Article
Antidepressants: Mechanism of action Geriatrics and Aging Verhoeff NPLG 1104555600 Journal Article
Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking Archives of General Psychiatry Staley JK, Gottschalk C, Petrakis IL, Gueorguieva R, O'Malley S, Baldwin R, Jatlow P, Verhoeff NP, Perry E, Weinzimmer D, Frohlich E, Ruff E, van Dyck CH, Seibyl JP, Innis RB, Krystal JH 1104555600 Journal Article
Acetylcholinergic neurotransmission and the β-amyloid cascade: Implications for Alzheimer's disease Expert Review of Neurotherapeutics Verhoeff NPLG 1104555600 Journal Article
Reduced serotonin 1a receptor binding potential and abnormal oral behaviors in frontotemporal degeneration Neurology Chow TW, Verhoeff NPLG, Takeshita S, Freedman M, Black S, Wilson A, Hussey D, Houle S, Meyer J 1104555600 Abstract
Traumatic brain injury and Alzheimer's disease Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Van Reekum R, Verhoeff NPLG 1104555600 Presentation
Traumatic brain injury and Alzheimer's disease Rotman Rounds Rapoport M, Van Reekum R, Verhoeff NPLG 1104555600 Presentation
What relevant aspects of the beta-amyloid cascade do we image with [11C]SB-13 PET? PET Centre Seminars at the Centre for Addiction and Mental Health, Clarke Site Honjo K, Verhoeff NPLG 1104555600 Presentation
Nuclear medicine: how can it help to optimize treatment for schizophrenia? Annual Scientific Congress of the European Association of Nuclear Medicine Verhoeff NPLG 1104555600 Presentation
Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade Department of Geriatric Psychiatry Grand Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG 1104555600 Presentation
Agitation and psychotic disorders in the elderly Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1104555600 Presentation
Neurological Examination for Psychiatrists Geriatric Psychiatry Residents' Seminar Day, Baycrest Centre for Geriatric Care Verhoeff NPLG 1104555600 Presentation
In vivo imaging of Alzheimer's disease beta-amyloid with [11C]SB-13 PET 31st Annual Harvey Stancer Research Day Verhoeff NPLG 1104555600 Presentation
Formulation Seminar for Geriatric Psychiatry Residents Baycrest Centre for Geriatric Care Verhoeff NPLG 1104555600 Presentation
Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade Neuroscience Rounds at at Sunnybrook and Women's College Health Sciences Centre Verhoeff NPLG 1104555600 Presentation
Cortical GABAA/Benzodiazepine Receptors in Recovery from Alcohol Dependence: Relationship to Features of Alcohol Dependence and Cigarette Smoking Addiction Psychiatry Rounds at the Centre for Addiction and Mental Health Verhoeff NPLG 1104555600 Presentation
Is there evidence from prospective cohort studies that apolipoprotein E epsilon 4 allele status affects the likelihood that traumatic brain injury will be followed by Alzheimer's disease? Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care Verhoeff NPLG 1104555600 Presentation
Effects of catecholamine depletion on D2 receptor binding, mood, attentiveness and personality in humans Rounds at the Department of Behavioural Neurology, Baycrest Centre for Geriatric Care Verhoeff NPLG 1104555600 Presentation
Cortical GABAA/benzodiazepine receptors in recovery from alcohol dependence: Relationship to features of alcohol dependence and cigarette smoking Kunin-Lunenfeld Applied Research Unit Rounds Verhoeff NPLG 1104555600 Presentation
Traumatic Brain Injury and Dementia Symposium American Association for Geriatric Psychiatry's 2005 Annual Meeting Rapoport MJ, Verhoeff NPLG, van Reekum R 1104555600 Presentation
Dopamine and psychomotor retardation in depression Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1104555600 Presentation
Alcohol and substance abuse in the elderly Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1104555600 Presentation
Benzodiazepine Receptor Imaging in Geriatric Neuropsychiatric Disorders Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG 1104555600 Presentation
In-vivo imaging of Alzheimer disease beta-amyloid with [C-11]SB-13 PET American Journal of Geriatric Psychiatry Verhoeff NPLG, Wilson AA, Takeshita S, Trop L, Hussey D, Singh K, Kung HF, Kung MP, Houle S 1099285200 Journal Article
Depression in frontotemporal dementia is associated with decreased left temporal lobe 5HT1a receptor density ANNALS OF NEUROLOGY Chow TW, Verhoeff NPLG, Takeshita S, St Jacques PL, Freedman M, Black SE, Wilson A, Hussey D, Houle S, Meyer J 1096862400 Abstract
Reduced serotonin 1a receptors in depressed frontotemporal lobar degeneration subjects Symposium for Frontotemporal Dementia Chow TW, Verhoeff NPLG, Takeshita S, Freedman M, Black SE, Wilson A, Hussey D, Houle S, Meyer J 1089691200 Presentation
Equivalent occupancy of dopamine D1 and D2 receptors with clozapine: differentiation from other atypical antipsychotics. American Journal of Psychiatry Tauscher J, Hussain T, Agid O, Verhoeff NP, Wilson AA, Houle S, Remington G, Zipursky RB, Kapur S 1072933200 Journal Article
Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder. Biological Psychiatry Fujita M, Southwick SM, Denucci CC, Zoghbi SS, Dillon MS, Baldwin RM, Bozkurt A, Kugaya A, Verhoeff NP, Seibyl JP, Innis RB 1072933200 Journal Article
Equivalent occupancy of dopamine D1 and D2 receptors differentiates clozapine from other atypicals American Journal of Psychiatry Tauscher J, Hussain T, Agid O, Verhoeff NPLG, Wilson AA, Houle S, Remington G, Zipursky RB, Kapur S 1072933200 Journal Article
Ligands for neuroreceptor imaging by positron or single-photon emission tomography Nuclear Medicine in Clinical Diagnosis and Treatment Verhoeff NPLG 1072933200 Book Chapter
I-Amyloid imaging in vivo and its possible implications for Alzheimer's disease Nuclear Medicine in Psychiatry Verhoeff NPLG, Wilson AA, Kung HF, Hussey D, Trop L, Houle S 1072933200 Book Chapter
Patient with visual hallucinations Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG, Mamelak M 1072933200 Presentation
Agitation and psychotic disorders in the elderly Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1072933200 Presentation
Beta-amyloid PET study: second progress report Neuroscience Rounds at Sunnybrook and Women's College Health Sciences Centre Verhoeff NPLG 1072933200 Presentation
Does hypothyroidism cause Alzheimer's disease? Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care Verhoeff NPLG 1072933200 Presentation
Beta-amyloid PET study: Second progress report Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site Verhoeff NPLG 1072933200 Presentation
The role of GABA in depression: cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT Kunin-Lunenfeld Applied Research Unit Rounds Verhoeff NPLG 1072933200 Presentation
The role of GABA in depression: cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1072933200 Presentation
Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG 1072933200 Presentation
The role of GABA in PTSD: Central type benzodiazepine receptors in Gulf war veterans with post-traumatic stress disorder Department of Geriatric Psychiatry Grand Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG 1072933200 Presentation
Acetylcholine and amyloid: connections between cholinergic neurotransmission and the beta-amyloid cascade Kunin-Lunenfeld Applied Research Unit Rounds Verhoeff NPLG 1072933200 Presentation
Beta-amyloid PET study: second progress report Kunin-Lunenfeld Applied Research Unit Rounds Verhoeff NPLG 1072933200 Presentation
Does traumatic brain injury induce cerebral beta-amyloidosis and does genetic ApoE status affect this induction? Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care Verhoeff NPLG 1072933200 Presentation
Alcohol and substance abuse in the elderly Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1072933200 Presentation
The role of GABA in depression: cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT Beta-amyloid PET study: second progress report Verhoeff NPLG 1072933200 Presentation
Beta-amyloid PET study: first progress report Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG 1072933200 Presentation
[11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? Rotman Rounds Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, St George-Hyslop P, Head E, Hussey D, Takeshita S, Trop L, Tapp D, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S 1072933200 Presentation
Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT. Biological Psychiatry Kugaya A, Sanacora G, Verhoeff NP, Fujita M, Mason GF, Seneca NM, Bozkurt A, Khan SA, Anand A, Degen K, Charney DS, Zoghbi SS, Baldwin RM, Seibyl JP, Innis RB 1066190400 Journal Article
11C-Labeled Stilbene Derivates as Aβ-aggregate-specific PET Imaging Agents for Alzheimer's disease Nuclear Medicine and Biology Ono M, Wilson A, Nobrega J, Westaway D, Verhoeff NPLG, Zhuang ZP, Kung MP, Kung HF 1059710400 Journal Article
Effects of catecholamine depletion on D2 receptor binding and mood in healthy humans Brain and Cognition Verhoeff NPLG, Hussey D, Lee M, Christensen BK, Papatheodorou G, Zipursky RB, Kapur S 1046494800 Journal Article
Effects of catecholamine depletion on D2 receptor binding, mood and attentiveness in humans: A replication study Pharmacology, Biochemistry and Behavior Verhoeff NPLG, Christensen BK, Hussey D, Lee M, Papatheodorou G, Kopala L, Rui Q, Zipursky RB, Kapur S 1041397200 Journal Article
Imaging antipsychotic action at dopamine receptors Dopamine Receptors and Transporters 2nd Edition Verhoeff NPLG, Kapur S 1041397200 Book Chapter
Do NSAIDs reduce the risk of developing AD? Canadian Academy of Geriatric Psychiatry Bulletin Verhoeff NPLG 1041397200 Journal Article
Serotonergic dysfunctions in schizophrenia Handbook of Medical Psychiatry Tauscher J, Verhoeff NPLG 1041397200 Book Chapter
Management of Agitation and Aggression in the Elderly Psychogeriatric Update 2003 at the Joseph E. and Minnie Wagman Centre, Baycrest Centre for Geriatric Care Verhoeff NPLG, Meier R, Mangar M, Wilkie T 1041397200 Presentation
[11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? Neuroscience Rounds at Sunnybrook and Women's College Health Sciences Centre Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S 1041397200 Presentation
[11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? PET Centre Seminars at the Centre for Addiction and Mental Health, Clarke Site Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S 1041397200 Presentation
[11C]SB-13 PET: A valid alternative for beta-amyloid imaging in vivo? Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S 1041397200 Presentation
[11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? Department of Geriatric Psychiatry Grand Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S 1041397200 Presentation
[11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? Kunin-Lunenfeld Applied Research Unit Rounds Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S 1041397200 Presentation
Can beta-amyloid PET assist in the prediction which Mild Cognitive Impairment patients will develop Alzheimer's disease? Evidence Based Clinical Practice Seminars Verhoeff NPLG 1041397200 Presentation
[11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S 1041397200 Presentation
[11C]SB-13 PET: a valid alternative for beta-amyloid imaging in vivo? VIth International Conference on Quantification of Brain Function with PET organized by the Society for Cerebral Blood Flow and Metabolism Verhoeff NPLG, Wilson AA, Nobrega J, Milgram NW, Westaway D, Head E, Hussey D, Tapp D, Trop L, Giuliano F, Araujo J, Ginovart N, Richardson L, Singh K, Kung HF, Kung MP, Houle S 1041397200 Presentation
Development of positron emission tomography tracers for beta-amyloid imaging in vivo and its possible implications for management of Alzheimer's disease Facilitating the Development of PET Diagnostics for Alzheimer's Disease Verhoeff NPLG 1041397200 Presentation
AMPT-induced catecholamine depletion in schizophrenic patients and control subjects Rotman Rounds Verhoeff NPLG 1041397200 Presentation
Is it likely that cholinesterase inhibitors (AChEI) decrease Abeta aggregation in Alzheimer's disease patients? Evidence Based Clinical Practice Seminars Verhoeff NPLG 1041397200 Presentation
Psychotic disorders in the elderly Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1041397200 Presentation
Beta-amyloid imaging in vivo Neuro-Geriatric Psychiatry Lecture Series at the Centre for Addiction and Mental Health, Queen Street Site Verhoeff NPLG 1041397200 Presentation
Beta-amyloid imaging in vivo Grand Rounds at Baycrest Centre for Geriatric Care Verhoeff NPLG 1041397200 Presentation
PET imaging of D1 and D2 receptors during treatment with novel antipsychotics European Neuropsychopharmacology Tauscher J, Agid O, Verhoeff NPLG, Harris P, Zipursky RB, Kapur S 1033444800 Abstract
Brain serotonin 5-HT1A receptor binding in schizophrenia measured by Positron Emission Tomography and [11C]WAY-100635 Archives of General Psychiatry Tauscher J, Kapur S, Verhoeff NPLG, Hussey DF, Daskalakis ZJ, Tauscher-Wisniewski S, Wilson AA, Houle S, Kasper S, Zipursky RB 1022904000 Journal Article
Dopamine depletion results in increased neostriatal D(2), but not D(1), receptor binding in humans Molecular Psychiatry Verhoeff NPLG, Hussey D, Lee M, Tauscher J, Papatheodorou G, Wilson AA, Houle S, Kapur S 1009861200 Journal Article
Depression Parkinson's Disease: Diagnosis and Clinical Management Chow TW, Verhoeff NPLG, Takeshita S, St Jacques PL, Freedman M, Black S, Wilson A, Hussey D, Houle S, Meyer J 1009861200 Book Chapter
Pharmacotherapy of agitation and psychotic symptoms in Alzheimer's disease Expert Review of Neurotherapeutics Verhoeff NPLG 1009861200 Journal Article
Dopamine depletion results in increased neostriatal D2 receptor binding in humans Molecular Psychiatry Verhoeff NPLG, Tauscher J, Jones C, Hussey D, Lee M, Papatheodorou G, Wilson AA, Houle S, Kapur S 1009861200 Journal Article
AMPT-induced catecholamine depletion in schizophrenic patients and control subjects Kunin-Lunenfeld Applied Research Unit Rounds Verhoeff NPLG 1009861200 Presentation
Do NSAIDs reduce the risk of developing Alzheimer's disease? Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care Verhoeff NPLG 1009861200 Presentation
Beta-amyloid imaging in vivo Kunin Lunenfeld Applied Research Unit 2nd Annual Conference on Alzheimer and Related Dementias: The Prevention of Disease, Morbidity, and Suffering Verhoeff NPLG 1009861200 Presentation
AMPT-induced catecholamine depletion in schizophrenic patients and control subjects Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site Verhoeff NPLG 1009861200 Presentation
Psychotic disorders in the elderly Geriatric Psychiatry Seminar Series at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1009861200 Presentation
Cortical GABAA/Benzodiazepine Receptors in Recovery from Alcohol Dependence: Relationship to Features of Alcohol Dependence and Cigarette Smoking Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG 1009861200 Presentation
Dopamine depletion in healthy subjects and in schizophrenic patients Educational Evening of the Behavioural Neurology Section of the Division of Neurology, University of Toronto Verhoeff NPLG 1009861200 Presentation
Effects of catecholamine depletion on D2 receptor binding, mood, attentiveness and personality in humans Grand Rounds at the Department of Geriatric Psychiatry, Baycrest Centre for Geriatric Care Verhoeff NPLG 1009861200 Presentation
Patient with prominent cognitive and mood symptoms Department of Behavioural Neurology Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG 1009861200 Presentation
A simple method to measure baseline occupancy of neostriatal dopamine D2 receptors by dopamine in vivo in healthy subjects Neuropsychopharmacology Verhoeff NPLG, Kapur S, Hussey D, Lee M, Christensen B, Papatheodorou G, Zipursky RB 996638400 Journal Article
Sensitivity of Voxel Based Comparisons for PET ligands with SPM Neuroimage Hussey D, Meyer JH, Kapur S, Verhoeff NPLG, Tauscher J, Cheung K, Houle S 991368000 Abstract
Serotonin 5-HT 1A receptor bnding potential declines with age as measured by [ 11 C]WAY-100635 and PET Neuropsychopharmacology Tauscher J, Verhoeff NPLG, Christensen B, Hussey D, Meyer JH, Kecojevic A, Javanmard M, Kasper S, Kapur S 988689600 Journal Article
Imaging of dopaminergic transmission in neuropsychiatric disorders Current Opinion in Psychiatry Verhoeff NPLG 988689600 Journal Article
PET imaging of serotonin 5-HT1A receptors in schizophrenia Schizophrenia Research Tauscher J, Kapur S, Verhoeff NP, Daskalakis ZJ, Tauscher-Wisniewski S, Papatheodorou G, Zipursky RB 987307200 Abstract
Neuroimaging and antipsychotics Journal of Pharmacy Practice Verhoeff NPLG, Kapur S 978325200 Journal Article
Radiotracer imaging of dopamine transporters and presynaptic dopamine synthesis in parkinsonian syndromes Brazilian Journal of Psychiatry Verhoeff NPLG 978325200 Journal Article
Efficacy and adverse effect rates of antipsychotics for agitation and psychosis in elderly patients with AD Evidence Based Clinical Practice Seminars, Baycrest Centre for Geriatric Care Verhoeff NPLG 978325200 Presentation
A voxel-by-voxel analysis of [18F]setoperone PET data shows no substantial serotonin 5-HT receptor 2A changes in schizophrenia Psychiatry Research: Neuroimaging Verhoeff NPLG, Meyer J, Kecojevic A, Hussey D, Lewis R, Tauscher J, Zipursky RB, Kapur S 972882000 Journal Article
Test-retest reproducibility of extrastriatal dopamine D2 receptor imaging with [123I]epidepride SPECT in humans. Journal of Nuclear Medicine Varrone A, Fujita M, Verhoeff NP, Zoghbi SS, Baldwin RM, Rajeevan N, Charney DS, Seibyl JP, Innis RB 965102400 Journal Article
Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients American Journal of Psychiatry Anand A, Verhoeff NPLG, Seneca N, Zoghbi SS, Seibyl JP, Charney DS, Innis RB 962424000 Journal Article
Linear regression analysis for PET/SPECT quantification of reversible neuroreceptor binding JOURNAL OF NUCLEAR MEDICINE Ichise M, Burger C, Stundzia A, Meyer JH, Verhoeff NP, Yonekura Y 960004800 Abstract
A voxel-by-voxel analysis of [F-18] setoperone PET serotonin(2A) receptor data in schizophrenia BIOLOGICAL PSYCHIATRY Verhoeff NPLG, Meyer JH, Kecojevic A, Hussey D, Lewis R, Kapur S 958017600 Abstract
Imaging extrastriatal dopamine D2 receptor occupancy by endogenous dopamine in healthy humans European Journal of Pharmacology Fujita M, Verhoeff NPLG, Varrone A, Zoghbi SS, Baldwin RM, Jatlow PA, Anderson GM, Seibyl JP 947480400 Journal Article
Dopamine depletion in healthy subjects Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site Verhoeff NPLG 946702800 Presentation
Benzodiazepine receptor imaging in neuropsychiatric disorders Kunin-Lunenfeld Applied Research Unit Rounds, Baycrest Centre for Geriatric Care Verhoeff NPLG 946702800 Presentation
Update on presentations at the American College of Neuropsychopharmacology meeting Schizophrenia Research Seminars at the Centre for Addiction and Mental Health, Clarke Site Verhoeff NPLG 946702800 Presentation
PET studies of serotonin receptors in Schizophrenia: Implications for pathophysiology and therapeutics XXIInd Meeting of the CINP Kapur S, Lewis R, Verhoeff NPLG, Jones C, Remington G, Zipursky R 946702800 Presentation
Kinetic and equilibrium analyses of [123I]epidepride binding to striatal and extrastriatal dopamine D2 receptors Synapse Fujita M, Seibyl JP, Verhoeff NP, Ichise M, Baldwin RM, Zoghbi SS, Burger C, Staley JK, Rajeevan N, Charney DS, Innis RB 945234000 Journal Article
Radiotracer imaging of dopaminergic transmission in neuropsychiatric disorders Psychopharmacology Verhoeff NPLG 944024400 Journal Article
Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D2 receptor binding with [123I]epidepride SPECT Journal of Nuclear Medicine Ichise M, Fujita M, Seibyl JP, Verhoeff NP, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB 941432400 Journal Article
Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D-2 receptor binding with [I-123]epidepride SPECT JOURNAL OF NUCLEAR MEDICINE Ichise M, Fujita M, Seibyl JP, Verhoeff NPLG, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB 941432400 Presentation
[123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia Psychiatry Research: Neuroimaging Verhoeff NPLG, Soares JC, D'Souza CD, Gil R, Degen K, Abi-Dargham A,Zoghbi SS, Fujita M, Rajeevan N, Seibyl JP, Krystal JH, van Dyck CH, Charney DS, Innis RB 939614400 Journal Article
Effects of vigabatrin on the GABA-ergic system as determined by [123I]iomazenil SPECT and GABA MRS Epilepsia Verhoeff NPLG, Petroff OAC, Hyder F, Zoghbi SS, Fujita M, Rajeevan N, Rothman DL, Seibyl JP, Mattson RH, Innis RB 938750400 Journal Article
Multilinear regression, graphical and simplified analyses of striatal and extrastriatal dopamine D-2 receptor binding with [I-123]epidepride SPECT JOURNAL OF NUCLEAR MEDICINE Ichise M, Fujita M, Seibyl JP, Verhoeff NP, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB 928641600 Abstract
Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans European Journal of Pharmacology Fujita M, Woods SW, Verhoeff NP, Abi-Dargham A, Baldwin RM, Zoghbi SS, Soares JC, Jatlow PA, Krystal JH, Rajeevan N, Charney DS, Seibyl JP, Innis RB 920610000 Journal Article
Functional Brain SPECT Imaging: 1999 and Beyond Nuclear Medicine Annual: 1999 Tikofsky RS, Ichise M, Seibyl JP, Verhoeff NPLG 915166800 Book Chapter
Graphical modeling of dopamine D2 receptor binding of 1-123-epidepride to account for labeled lipophilic metabolites JOURNAL OF NUCLEAR MEDICINE Ichise M, Fujita M, Seibyl JP, Verhoeff NP, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB 897192000 Abstract
Benzodiazepine brain SPECT: clinical application Society of Nuclear Medicine 1998 Handout Book Wednesday and Thursday Courses Verhoeff NPLG 883630800 Book Chapter
Benzodiazepine receptor binding and schizophrenia. American Journal of Psychiatry Verhoeff NP 875678400 Journal Article
Neuroreceptor ligand imaging by SPECT in Parkinsonian syndromes A Textbook of SPECT in Neurology and Psychiatry Verhoeff NPLG, Booij U, Innis RB, Van Royen EA 852094800 Book Chapter
Clinical significance of dopamine D2-receptor imaging with 123I-iodobenzamide SPECT in patients with Parkinsonian syndromes A Textbook of SPECT in Neurology and Psychiatry Verhoeff NPLG, Speelman JD, Kuiper MA, Van Royen EA, DKapucu O, Boer GJ, Janssen AGM, Wolters ECH 852094800 Book Chapter
Potential for imaging cerebral amyloid deposits using 123I-labelled serum amyloid P component and SPET. Nuclear Medicine Communications Bornebroek M, Verzijlbergen JF, Haan J, Van Scheyen EJ, Verhoeff NP, Pauwels EK, Roos RA 846824400 Journal Article
Indium-111-DTPA-octreotide uptake measured in normal and abnormal pituitary glands Journal of Nuclear Medicine van Royen EA, Verhoeff NP, Meylaerts SA, Miedema AR 841550400 Journal Article
Dopamine D2 receptor blockade in vivo with the novel antipsychotics risperidone and remoxipride: An 123I-IBZM single photon emission tomography (SPET) study. Psychopharmacology Busatto GF, Pilowsky LS, Costa DC, Ell PJ, Verhoeff NP, Kerwin RW 788936400 Journal Article
Brain SPECT Imaging in Psychiatry Neuroimaging in Schizophrenia Verhoeff NPLG 788936400 Book Chapter
123I-IBZM SPECT Brain Imaging in Schizophrenia Brain SPECT Imaging in Psychiatry Lucey JV, Pilowsky LS, Costa DC, Ell PJ, Verhoeff NPLG, Kerwin RW 788936400 Book Chapter
Dopamine receptor availability in Tourette's syndrome Psychiatry Research - Neuroimaging George MS, Robertson MM, Costa DC, Ell PJ, Trimble MR, Pilowsky L, Verhoeff NP 786258000 Journal Article
No direct correlation between behaviorally active doses of the dopamine D2 agonist LY 171555 and displacement of [123I]IBZM as measured with SPECT in MPTP monkeys Synapse Vermeulen RJ, Drukarch B, Verhoeff NP, Goosen C, Sahadat MC, Wolters EC, van Royen EA, Stoof JC 770443200 Journal Article
Stereotypy, schizophrenia and dopamine D2 receptor binding in the basal ganglia Psychological Medicine Pedro BM, Pilowsky LS, Costa DC, Hemsley DR, Ell PJ, Verhoeff NP, Kerwin RW, Gray NS 767764800 Journal Article
Striatal dopamine receptor binding in epileptic psychoses Biological Psychiatry Ring HA, Trimble MR, Costa DC, Moriarty J, Verhoeff NP, Ell PJ 763707600 Journal Article
D2 dopamine receptor binding in the basal ganglia of antipsychotic-free schizophrenic patients. An 123I-IBZM single photon emission computerised tomography study. British Journal of Psychiatry Pilowsky LS, Costa DC, Ell PJ, Verhoeff NP, Murray RM, Kerwin RW 757400400 Journal Article
Ligands for neuroreceptor imaging by single photon emission tomography (SPET) or positron emission tomography (PET) Nuclear Medicine in Clinical Diagnosis and Treatment Verhoeff NPLG 757400400 Book Chapter
Estimation of dopamine D2 receptor binding potential in the striatum with iodine-123-IBZM SPECT:Technical and interobserver variability Journal of Nuclear Medicine Verhoeff NPLG, Kapucu O, Sokole-Busemann E, Van Royen EA, Janssen AGM 754722000 Journal Article
Dopamine D2 receptor occupancy in vivo and response to the new antipsychotic risperidone. British Journal of Psychiatry Kerwin RW, Busatto GF, Pilowsky LS, Ell PJ, Costa DC, Verhoeff NP, Kerwin RW 754722000 Journal Article
Dopamine D2-receptor imaging with 123I-iodobenzamide SPECT in migraine patients abusing ergotamine: does ergotamine cross the blood brain barrier? Cephalalgia Verhoeff NPLG, Visser WH, Ferrari MD, Saxena PR, Van Royen EA 749448000 Journal Article
Dosimetry of iodine-123 iodobenzamide in healthy volunteers European Journal of Nuclear Medicine Verhoeff NPLG, Busemann Sokole E, Stabin M, Hengst D, Kung HF, Van Royen EA, Janssen AGM 746856000 Journal Article
Quantification of central benzodiazepine receptor binding potential in the brain with 123I-iomazenil SPECT - technical and interobserver variability Nuclear Medicine Communications Verhoeff NPLG, Erbas B, Kapucu O, Busemann Sokole E, Blok H, Van Royen EA 744177600 Journal Article
Antipsychotic medication, D2 dopamine receptor blockade and clinical response: a 123I IBZM SPET (single photon emission tomography) study Psychological Medicine Pilowsky LS, Costa DC, Ell PJ, Murray RM, Verhoeff NPLG, Kerwin RW 744177600 Journal Article
Imaging of dopamine D2 and somatostatin receptors in vivo using single-photon emission tomography in a patient with a TSH/PRL-producing pituitary macroadenoma European Journal of Nuclear Medicine Verhoeff NPLG, Bemelman FJ, Wiersinga WM, Van Royen EA 738907200 Journal Article
Intracranial dissemination of a macroprolactinoma Clinical Endocrinology Assies J, Verhoeff NP, Bosch DA, Hofland LJ 736228800 Journal Article
Multiple system atrophy and progressive supranuclear palsy. Diminished striatal D2 dopamine receptor activity demonstrated by 123I-IBZM single photon emission computed tomography Archives of Neurology Van Royen EA, Verhoeff NPLG, Speelman JD, Wolters EChMJ, Kuiper MA, Janssen AG 736228800 Journal Article
123I-SCH 23982 is not suitable for dopamine D1 receptor imaging in vivo in the human brain Nuclear Medicine Communications Verhoeff NPLG, Bekier A, Beer HF, Schubiger PA, Fennema P, Van Royen EA 728542800 Journal Article
Spectral analysis of the EEG and 99mTc-HMPAO SPECT-scan in Alzheimer's disease Biological Psychiatry Kwa VIH, Weinstein HC, Posthumus Meyjes FE, Van Royen EA, Bour LJ, Verhoeff NPLG, Ongerboer de Visser BW 727074000 Journal Article
Neuroreceptor ligand imaging by Single Photon Emission Computerised Tomography (SPECT) Nuclear Medicine Bulletin Verhoeff NPLG 725864400 Journal Article
In vitro and in vivo binding of muscarinic cholinergic receptors with 123I-Iododexetimide in rat brain and heart Nuclear Medicine Bulletin Verhoeff NPLG, Bobeldijk M, Van Breukel AIM, Van Vlies B, Maas MAW, Boer GJ,Feenstra MGP, Erdtsieck-Ernste E, DeBruin K, Olivier G, Van Royen EA 725864400 Journal Article
Dosimetry of iodine-123 iomazenil in humans European Journal of Nuclear Medicine Verhoeff NPLG, Busemann Sokole E, Hengst D, Stubbs JB, Van Royen EA 725864400 Journal Article
Dynamic studies of the binding of 123I-Iomazenil to central benzodiazepine receptors in healthy volunteers Nuclear Medicine Bulletin Verhoeff NPLG, Van Royen EA, Overweg J, Limburg M, Stam J, Roolker L, Wiggerts HO, Beer HF 725864400 Journal Article
Imaging neurotransmission and neuroreceptors - physiological and pharmacological basis New Trends in Nuclear Neurology and Psychiatry Verhoeff NPLG 725864400 Book Chapter
Neuroreceptor ligand imaging by single photon emission computerised tomography (SPECT) Thesis University of Amsterdam Verhoeff NPLG 725864400 Book Chapter
Effect of vigabatrin on striatal dopamine receptors: evidence in humans for interactions of GABA and dopamine systems Journal of Neurology, Neurosurgery & Psychiatry Ring HA, Trimble MR, George MS, Costa DC, Verhoeff NPLG, Ell PJ 715320000 Journal Article
Basics and recommendations for brain SPECT. Task Group "Neurology" of the European Association of Nuclear Medicine. Nuclear Medicine Verhoeff NPLG, Büll U, Costa DC, Kirsch G, Lottes G, Moretti JL, Podreka I, Schober O, Van Royen EA 712641600 Journal Article
Clozapine, single photon emission tomography, and the D2 dopamine receptor blockade hyopothesis of schizophrenia Lancet Pilowsky LS, Costa DC, Ell PJ, Murray RM, Verhoeff NPLG, Kerwin RW 712036800 Journal Article
Nedocromil sodium inhibits the early and late asthmatic response to exercise European Respiratory Journal Speelberg B, Verhoeff NP, van den Berg NJ, Oosthoek CH, van Herwaarden CL, Bruijnzeel PL 702104400 Journal Article
Focus localization in patients with partial epilepsy with 99Tcm-HMPAO SPECT under continuous surface EEG monitoring Nuclear Medicine Communications Verhoeff NPLG, Weinstein HC, Aldenkamp AP, Overweg J, Van Royen EA, Verbeeten B Jr 699426000 Journal Article
Cell biology from a medical perspective. X. Signal transduction Nederlands tijdschrift voor geneeskunde Verhoeff NP 699426000 Journal Article
Parkinson disease, a simple diagnosis? Nederlands tijdschrift voor geneeskunde Verhoeff NP, van Royen EA, Speelman JD, Wolters EC, Kuiper MA 699426000 Journal Article
[The suppressed pill with far-reaching consequences] Nederlands tijdschrift voor geneeskunde Verhoeff NP 696920400 Journal Article
Memory complaints, memory disorders and focus localization in patients with partial epilepsy Seizure Verhoeff NPLG, Aldenkamp AP, Overweg J, Van Royen EA, Verbeeten B Jr, Weinstein HC 694242000 Journal Article
Asthma in children; consensus by pediatric pneumonologists about long-term treatment Nederlands tijdschrift voor geneeskunde Verhoeff NP 694242000 Journal Article
Dopamine D2 receptor availability in patients with Gilles de la Tourette syndrome studied with SPET Nuclear Medicine in Research and Practice, European Nuclear Medicine Congress, Vienna, September 1-5, 1991 Costa DC, George MS, Ell PJ, Pilowshy L, Verhoeff NPLG, Robertson MM 694242000 Book Chapter
In vitro and in vivo binding of muscarinic cholinergic receptors with 123I-Iododexetimide in rat brain and heart Nuclear Medicine in Research and Practice Verhoeff NPLG, Bobeldijk M, Van Breukel AIM, Fan Vlies B, Maas MAW, Boer GJ, Feenstra MGP, Erdtsieck-Ernste E, DeBruin K, Olivier G, Van Royen EA 694242000 Book Chapter
Validity of computerized testing - patient dysfunction and complaints versus measured changes The Assessment of Cognitive Function in Epilepsy Aldenkamp AP, Vermeulen J, Alpherts WCJ, Overweg J, Van Parijs JAP, Verhoeff NPLG 694242000 Book Chapter
Effect of vigabatrin on striatal dopamine receptors Nuclear Medicine in Research and Practice Ring HA, Trimble MR, Costa DC, George MS, Verhoeff P, Ell PJ 694242000 Book Chapter
Dynamic SPECT in two healthy volunteers to determine the optimal time for in vivo D2 dopamine receptor imaging with 123I-IBZM using the rotating gamma camera Nuclear Medicine Communications Verhoeff NPLG, Brücke T, Podreka I, Bobeldijk M, Angelberger P, Van Royen EA 681019200 Journal Article
Evaluation of a multicentre study with Iomazenil- a benzodiazepine receptor ligand Nuclear Medicine Communications Schubiger PA, Hasler PH, Beer-Wohlfahrt H, Bejier A, Oettli R, Cordes M, Ferstl F, Deisenhammer E, De Roo M, Moser E, Nitzsche E, Podreka I, Riccabona G, Bangerl I, Schober O, Bartenstein P, Van Rijk P, Van Isselt JW, Van Royen EA, Verhoeff NPLG, Haldemann R, Von Schultess GK 678340800 Journal Article
Dopamine D2-receptor imaging with dynamic I-123 IBZM SPET in patients with schizophrenia or HIV encephalopathy Nuclear Medicine : The State Of The Art Of Nuclear Medicine In European Verhoeff NPLG, Costa DC, Ell PJ, Toone B, Palasidou E, Cullum ID, Bobeldij M, Miller R, Syed GMS, Barrett JJ, Soricelli A, Van Royen EA 662706000 Book Chapter
Hersenfunctieonderzoek met behulp van isotopen Medical Technology Verhoeff NPLG 662706000 Journal Article
Pharmacological implications for neuroreceptor imaging European Journal of Nuclear Medicine Verhoeff NPLG 662706000 Journal Article
Benzodiazepine receptor density in human brain measured in vivo with I-123 iomazenil SPECT Nuclear Medicine : The State Of The Art Of Nuclear Medicine In European Verhoeff NPLG, Van Royen EA, Ell PJ, Costa DC, Hasler PH, Schubiger PA 662706000 Book Chapter
In vitro and in vivo D2-dopamine receptor binding with [123I]S(-)iodobenzamide ([123I]IBZM) in rat and human brain Nuclear Medicine and Biology - Part B: International Journal of Radiation Applications and Instrumentation Verhoeff NP, Bobeldijk M, Feenstra MG, Boer GJ, Maas MA, Erdtsieck-Ernste E, de Bruin K, van Royen EA 662706000 Journal Article
A simple and high-yield synthesis of (S)-BZM, (R)-BZM and (S)-IBZM for the preparation of (S)-123I-IBZM Journal of Labelled Compounds and Radiopharmaceuticals Bobeldijk M, Verhoeff NPLG, Vekemans JAJM, Buck HM, Van Doremalen PAPM, Van Hoof JJ, Janssen AGM 657435600 Journal Article
Real and pseudo late asthmatic reactions after submaximal exercise challenge in patients with bronchial asthma. A new definition for late asthmatic responses after exercise challenge Chest Verhoeff NPLG, Speelberg B, Van den Berg NJ, Oosthoek CHA, Stijnen T 657435600 Journal Article
In vivo characterisation of 3-iodo-6-methoxybenzamide 123I in humans European Journal of Nuclear Medicine Costa DC, Verhoeff NP, Cullum ID, Ell PJ, Syed GM, Barrett J, Palazidou E, Toone B, Van Royen E, Bobeldijk M 646804800 Journal Article
A comparison of Tl-201-DDC and Tc-99m-HMPAO SPECT in patients with ischemic stroke or dementia Nuclear Medicine Bulletin Verhoeff NPLG, Van Kanten J, Van der Zant FM, Van Royen EA, Weinstein H, Limburg M 631170000 Journal Article
A comparison of Tl-201-DDC and Tc-99m-HMPAO SPECT in patients with ischemic stroke or dementia The State of the Art of Nuclear Medicine in Europe Verhoeff NPLG, Van Kanten J, Fan der Zant FM, Van Royen EA, Weinstein H, Limburg M 631170000 Book Chapter
Benzodiazepine receptor density in human brain measured in vivo with 123-Iomazenil SPECT The State of the Art of Nuclear Medicine in Europe Verhoeff NPLG, Van Royen EA, Ell PJ, Costa C, Hasler PH, Schubiger PA 631170000 Book Chapter
Immediate and late asthmatic responses induced by exercise in patients with reversible airflow limitation European Respiratory Journal Speelberg B, van den Berg NJ, Oosthoek CH, Verhoeff NP, van den Brink WT 609998400 Journal Article
The prevalence of the early and late asthmatic reaction after exercise in patients with intrinsic and extrinsic asthma Agents and Actions Supplement Speelberg B, Verhoeff NP, van den Brink WT 599634000 Journal Article
Benzodiazepine receptor density in human cerebral cortex and cerebellum measured in vivo with 123I-Iomazenil SPECT Iomazenil and Other Brain Receptor Tracers for SPECT, Proceedings of the 6th Bottstein Colloquim, Wurenlingen Villigen, Switzerland Verhoeff NPLG, Van Royen EA, Overweg J, Limburg M, Hijdra A, Linszen D 599634000 Book Chapter

Education

  • 2003: Diplomate of the American Board of Psychiatry and Neurology, Inc., Member Board of the American Board of Medical Specialties, (# 53130 )
  • 2003: Examination Part II, American Board of Psychiatry and Neurology
  • 2002: Certificate of Registration for Independent, Practice from the College of Physicians and Surgeons of Ontario (# 74459)
  • 2001: Licentiate of the Medical Council of Canada, Canadian Medical Register (# 91136 )
  • 2001: Qualifying Examination Part II , Medical Council of Canada (# 9980517)

Academic Appointments

  • 2005–Present: Associate Professor of Psychiatry, Department of Psychiatry, Geriatric Program, University of Toronto, Toronto, Ontario, Canada (# 1016849 )
  • 2003–Present: Staff Psychiatrist, Brain Health Centre, Behavioural Neurology Memory Disorders Clinic, and Geriatric Psychiatry Community Service, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
  • 2001–Present: Neuropsychiatry Clinician-Scientist and Staff Psychiatrist, Kunin-Lunenfeld Applied Research Unit, Geriatric Psychiatry Community Service, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada

Reviewership

Consulting

  • 1992: European Journal of Nuclear Medicine
  • 1999: Psychopharmacology
  • 2001: American Journal of Psychiatry
  • 2001: Journal of Neurochemistry
  • 2000–2001: Journal of Neuropsychiatry and Clinical Neurosciences
  • 2003: Journal of Neuropsychiatry and Clinical Neurosciences
  • 2001–2003: Journal of Psychiatry and Neuroscience
  • 2002: NeuroImage
  • 2002: Archives of General Psychiatry
  • 2003–2010: American Journal of Geriatric Psychiatry
  • 2005: American Journal of Geriatric Psychiatry
  • 2000: Neuropsychopharmacology
  • 2000–2003: Psychiatry Research: Neuroimaging
  • 2003: Biological Psychiatry
  • 2004: Brain

Committee

  • 2010: Thesis (Dr. Christina Siwak, PhD (2002). Thesis: Age-related changes in non-cognitive behaviours in a canine model of aging and dementia and therapeutic evaluation of adrafinil and modafinil. )
  • 2010: Thesis (Ms. Jennifer Glass, MSc (2002-present). Thesis: Clinical effects of benzodiazepines in the elderly. )
  • 2010: Thesis (Ms. Pearl Behl, MSc (2004-present). Thesis: Longitudinal effects of cholinergic therapy on Alzheimer’s disease (AD)- a neurobehavioral, structural and functional imaging study. )
  • 2010: Thesis (Matthew Parrott (2005-present). Thesis: Postprandial memory response in MCI/MCI-like subjects.)
  • 2010: European Association of Nuclear Medicine Neuroimaging Committee (Professional Committee )
  • 2004: National Institutes of Health – National Institute of Aging Review Committee member (Professional Committee: "reverse" site visit from July 29-30, 2004, in Bethesda, MD, USA, to review a Program Project Grant application by the University of Pittsburgh School of Medicine on behalf of Dr. Steven DeKosky, MD, PhD: "In Vivo PIB PET Amyloid Imaging: Normals, MCI & Dementia." )
  • 2004: National Institutes of Health – National Institute of Aging Review Committee member (Professional Committee: "reverse" site visit from November 2-3, 2004, in Bethesda, MD, USA, to review a Program Project Grant application by the University College of Los Angeles on behalf of Dr. Gary Small, MD: "Amyloid Imaging in Aging.")

Membership

  • 2010: American Psychiatric Association (Member # 80011 )
  • 2010: Canadian Medical Association (Member # 120718)
  • 2010: Ontario Medical Association (Member # 079-4834)
  • 2010: Canadian Medical Protective Association (Member # 1001169)
  • 2010: Scientific Review Board of the Institute for the Study of Aging

Distinctions and Awards

  • 2005: Outstanding Service Award, Baycrest Centre for Geriatric Care, Employee Recognition and Rewards Committee Implementation Team at Baycrest Centre for clinical services provided at the Brain Health Centre Memory Disorders Clinic, April 29, 2005 , 75.00
  • 2004: Alzheimer’s Association Travel Fellowship 2004, 9th International Conference on Alzheimer's Disease and Related Disorders, USD. July 17-22, 2004, Philadelphia, Pennsylvania, USA, 645
  • 2003: International Junior Investigator Award 2003, International College of Geriatric Psychoneuropharmacology (ICGP) , USD. Provided at the International College of Geriatric Psychoneuropharmacology 3rd Annual Meeting, December 12-14, 2003 San Juan, Puerto Rico. , 2,000
  • 1999: American Psychiatric Association/Lilly Resident Research Award 1998-1999, American Psychiatric Association annual meeting, USD. Washington, DC , 1,500
  • 1998: American College of Neuropsychopharmacology (ACNP) Travel Award 1998, Bristol-Myers-Squibb and the American College of Neuropsychopharmacology 37th annual meeting, USD. Las Croabas, Puerto Rico , 2,000
  • 1990: Mallinckrodt-Award 1990 - best presentation from the Benelux, Congress of the European Association of Nuclear Medicine in Amsterdam, Hfl (Dutch guilders), 2,500

Research Projects

External

  • 2004–2006: β-amyloid PET imaging in Alzheimer’s disease

    Sponsors: Alzheimer’s Association New Investigator Research Grant, 100,000 (USD)

  • 2003–2006: Beta amyloid PET imaging in vivo for early detection of Alzheimer's disease

    Sponsors: Scottish Rite Charitable Foundation of Canada’s Major Research Grant, 104,983 (CAD)

  • 2002–2004: Imaging amyloid plaques with PET in patients with Alzheimer’s disease

    Sponsors: Alzheimer Society of Canada Young Investigator Grant, 50,000 (CAD)

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Curriculum Vitae

Contact

Kunin-Lunenfeld Applied Research Unit
Baycrest
3560 Bathurst Street, 762
Toronto, Ontario
Canada M6A 2E1 Email: PVerhoeff@baycrest.org