Williams, Lynne J. Dr.
Dr. Lynne Williams, PhD
fMRI Specialist and Program Manager Centre for Brain Fitness, Rotman Research Institute, Baycrest
Research Focus
My research interests are in the cognitive neuroscience of language development over the lifespan and in developing statistical techniques to analyse multivariate data as found, for example, in functional brain imaging (including fMRI, MEG, fNIRS and EEG) and discourse analysis (e.g., multi-block discriminant correspondence analysis, partial least squares analysis). My most recent work is concerned with pattern classifiers in brain imaging, changes and variability in brain activation and behaviour in ageing and dementia, and the development of semantic and conceptual representations across the lifespan.
Publications
| Title | Source (Journal/Book/Conference) | Authors/Presenters | Published On | Type |
|---|---|---|---|---|
| Multiple factor analysis: principal component analysis for multi-table and multi-block data sets | Wiley Interdisciplinary Reviews Computational Statistics | Abdi H, Williams LJ, Valentin D | 1357016400 | Journal Article |
| The Survey of Autobiographical Memory (SAM): A novel measure of trait mnemonics in everyday life. | Cortex | Palombo D, Williams L, Abdi H, Levine B | 1347422400 | Journal Article |
| Partial least squares methods: Partial least squares correlation and partial least square regression | Methods in Molecular Biology: Computational Toxicology | Abdi H, Williams LJ | 1342411200 | Book Chapter |
| Effect of Age on Variability in the Production of Text-Based Global Inferences | PLoS ONE | Williams LJ, Dunlop JP, Abdi H | 1338609600 | Journal Article |
| Analysis of regional cerebral blood flow data to discriminate among Alzheimer's disease, fronto-temporal dementia, and elderly controls: A multi-block barycentric discriminant analysis (MUBADA) methodology | Journal of Alzheimer Disease | Abdi H, Williams LJ, Beaton D, Posamentier M, Harris TS, Krishnan A, Devous MD | 1338523200 | Journal Article |
| Multiple Subject Barycentric Discriminant Analysis (MUSUBADA): How to assign scans to categories without using spatial normalization | Computational and Mathematical Methods in Medicine | Abdi H, Williams LJ, Connolly AC, Gobbini MI, Dunlop JP, Haxby JV | 1334030400 | Journal Article |
| STATIS and DISTATIS: optimum multitable principal component analysis and three way metric multidimensional scaling | Wiley Interdisciplinary Reviews: Computational Statistics | Abdi H, Williams LJ, Valentin D, Bennani-Dosse M | 1329368400 | Journal Article |
| Neural circuitry of emotional processing in late-life depression | Human Brain Mapping | Mah L, Williams LJ, Leung R, Freel S, Pollock B | 1302235200 | Abstract |
| Neural substrates of emotional processing in late-life depression. | Biological Psychiatry | Mah L, Williams LJ, Leung R, Freel S, Pollock B | 1302235200 | Abstract |
| Partial Least Squares (PLS) methods for neuroimaging: A tutorial and review | NeuroImage | Krishnan A, Williams LJ, McIntosh AR, Abdi H | 1296277200 | Journal Article |
| Effects of Animal Assisted Therapy on Conversation in a Married Couple with Alzheimer’s Disease | International Ethological Conference | Orange JB, Robertson C, Williams LJ | 1288324800 | Presentation |
| Group differences in response patterns on a measure of conversational skills in dementia | International Association of Gerontology and Geriatrics | Orange JB, Williams LJ, Lubinski R, Purves B, Johnson A, Small J | 1288324800 | Presentation |
| How to compute reliability estimates and display confidence and tolerance intervals for pattern classifiers using the Bootstrap and 3-way multidimensional scaling (DISTATIS) | NeuroImage | Abdi H, Dunlop JP, Williams LJ | 1287720000 | Journal Article |
| Coefficients of correlation, alienation, and determination | Encyclopedia of Research Design | Abdi H, Williams LJ | 1287720000 | Book Chapter |
| Contrast analysis | Encyclopedia of Research Design | Abdi H, Williams LJ | 1287720000 | Book Chapter |
| Correspondence analysis | Encyclopedia of Research Design | Abdi H, Williams LJ | 1287720000 | Book Chapter |
| Fisher's least significance difference (LSD) test | Encyclopedia of Research Design | Williams LJ, Abdi H | 1287720000 | Book Chapter |
| Honestly significant difference (HSD) test | Encyclopedia of Research Design | Abdi H, Williams LJ | 1287720000 | Book Chapter |
| Jackknife | Encyclopedia of Research Design | Abdi H, Williams LJ | 1287720000 | Book Chapter |
| Matrix algebra | Encyclopedia of Research Design | Abdi H, Williams LJ | 1287720000 | Book Chapter |
| Newman-Keuls and Tukey test | Encyclopedia of Research Design | Abdi H, Williams LJ | 1287720000 | Book Chapter |
| Normalizing data | Encyclopedia of Research Design | Abdi H, Williams LJ | 1287720000 | Book Chapter |
| Post-hoc comparisons | Encyclopedia of Research Design | Williams LJ, Abdi H | 1287720000 | Book Chapter |
| A tutorial on multiblock discriminant correspondence analysis (MUDICA): A new method for analyzing discourse data from clinical populations | Journal of Speech, Language, and Hearing Research | Williams LJ, Abdi H, French R, Orange JB | 1285905600 | Journal Article |
| Barycentric discriminant analysis (BADIA) | Encyclopedia of Research Design | Abdi H, Williams LJ | 1280635200 | Book Chapter |
| Principal component analysis | Wiley Interdisciplinary Reviews: Computational Statistics | Abdi H, Williams LJ | 1277956800 | Journal Article |
| Barycentric Discriminant Analysis (BDA): a new pattern recognition classifier that identifies voxels and regions of interest relevant for classification of functional brain imaging data | Human Brain Mapping | Devous MD, Abdi H, Williams LJ, Posamentier M, Harris TS | 1245297600 | Abstract |
| Holistic assessment of narrative quality: A social validation study | Aphasiology | Olness GS, Ulatowska HK, Carpenter C, Williams-Hubbard LJ, Dykes JC | 1116734400 | Journal Article |
| Coherence of narratives in aphasia | Brain and Language | Ulatowska HK, Olness GS, Williams LJ | 1098417600 | Journal Article |
| Evaluation of the effectiveness of two clinical training procedures to elicit yes/no responses from patients with a severe acquired brain injury: A randomized single-subject design | Brain Injury | Barreca S, Velikonja D, Brown L, Williams LJ, Davis L, Sigouin C | 1066795200 | Journal Article |
Education
- 2007: Ph.D., University of Texas at Dallas, Richardson, Texas USA
- 2000: M.Sc, University of Western Ontario, London, Ontario CANADA
- 1995: B.A., University of British Columbia, Vancouver, British Columbia CANADA
Academic Appointments
- 2012–Present: fMRI Specialist and Program Manager, Centre for Brain Fitness, Rotman Research Institute, Baycrest
Reviewership
Membership
Other
- NeuroImage
Research Projects
External
-
2010–2011:
Early Researcher Award
Supervisor: Cheryl Grady
Collaborators: Hervé Abdi, JB Orange, Micheal Devous Sr.
Institutions: Baycrest Centre for Geriatric CareSponsors: Ontario Research Coalition of Research Institutes/Centres on Aging (ORC), $2,000 (CAD)
Fellowship -
1998–2000:
Supervisor: J.B. Orange
Institutions: University of Western OntarioSponsors: Ontario Neurotrauma Foundation, $20,000 (CAD)
Fellowship
Curriculum Vitae
Contact
3560 Bathurst StreetToronto, Ontario M6A 2E1
Canada Phone: 416-785-2500 ext. 3149 Email: lwilliams
research.baycrest.org
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