Takako Fujioka

Dr. Takako Fujioka

Scientific Associate Rotman Research Institute, Baycrest

Research Focus

My research is focused on determining how brain understands sound as music, and how the brain benefits from music in normal population across lifespan and possible patients groups.

The main questions we address here are the following:

  1. How musical features such as pitch, melody, rhythm, and meter are processed in the brain?
  2. How does these brain functions differ between musicians and non-musicians?
  3. Does musical experience have life enhancing effects in the developing, aging, or damaged brain?

By using non-invasive brain imaging techniques of magnetoencephalography (MEG) and structural magnetic resonance imaging (MRI), we address the first question by examining neural responses to sound and musical stimuli.  We have identified that the auditory cortex in both left and right hemispheres contributes to encode melodic contours and intervals, and two simultaneously presented melodies separately. We also have identified the brain responses reflect how we predict time of the isochronous beats and subjective meter.

The second question is tested by studies of comparing the brain responses of musician and non-musician in children and young adult. We investigate whether musicians show enhanced representations of musical stimuli (tone, melody, harmony or cross-modal audio-motor task) as reflected in the brain responses.

Then the third question will be answered by the studies in which brain functions are compared before and after musical experiences. Since the projects have begun, the data have started to give us new evidence of expertise effect in young ages. In particular, ongoing studies address possible effects of 'music-supported stroke rehabilitation' on behavioural (cognitive, affective, quality of life) and brain functions spanning auditory, sensory, and motor systems.


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News & Updates

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NEWS (Mar 22, 2012): Our application to Grant-in-Aid competition at Heart and Stroke Foundation of Ontario (HSFO)
 "Examination of the intensity of music-supported stroke rehabilitation" has won $139,998.00 in total
for 2 years

NEWS(Feb 20, 2012):  The Globe and Mail featured our project! http://www.theglobeandmail.com/life/health/new-health/conditions/brain-health/tapping-musics-power-to-heal-the-brain/article2342397/

NEWS (Jan 27, 2012): Canadian Institutes of Health Research (CIHR) Operating Grant  "Impact of music-supported rehabilitation on behavioural and cortical functions in stroke recovery" is funded $461.247 total for 3 years.


NEWS (Dec 14, 2011) : I will be on the panel for a symposium 'Music, science, technology' organized by a prominent composer Dr. Norbert Palej (U of Toronto) as part of 'New Music Festival' on January 25, noon, at Faculty of Music U of Toronto.

NEWS (Dec 14, 2011): I will be presenting a scientific talk at Toronto Western Hospital Neuroimaging round on Jan 17, 9am. "Beta-band neuromagnetic oscillatory network for timing processing, and their plasticity in music-supported stroke rehabilitation".


NEWS (July 6/2011): Lendra Friesen, her colleagues (Sunnybrook) and me got a grant! Med-El Hearing Solutions (MHS) Research Grants for the Basic Sciences in Hearing EUR 100,000 x 2years, PI Lendra Friesen (Sunnybrook HSC) Co-applicants: Takako Fujioka (Rotman) Vincent Lin& David Shipp (Sunnybrook Otolaryngology) "Age-related Changes in the Effects of Stimulation Rates on Cortical Processing and Speech Recognition in Cochlear Implant (CI) Listeners".

NEWS (July 1st/2011): We got CIHR operating funding $789,839 in total for 5 years. Co-PIs: Laurel Trainor (McMaster U) & Takako Fujioka (Rotman) with Co-applicants:Geoff Hall& Larry Roberts (McMaster U) "Oscillatory networks for rhythmic timing in auditory and motor regions: Interaction, development and plasticity"

NEWS (June 21/2011): I will be presenting one of symposium talks in "The Sixth Conference on Mismatch Negativity (MMN) and its Clinical and Scientific Application"  May 1-4, 2012 at The Graduate Center, City University of New York.

NEWS (Feb 14/2011): I will be presenting a poster at New York Academy of Science special conference ''Music, Science & Medicine: Frontiers in Biomedical Research & Clinical Applications' March 25, 2011.

NEWS (Jan 10/2011): I will be performing piano for Music Therapy Week event at Baycrest on March 7, 2011, Monday. The time TBA.

NEWS (Dec 24/2010): I will be a symposium chair organizing "The role of music in stroke rehabilitation: neural mechanisms and therapeutic techniques" in Neuroscience and Music IV conference in Edinburgh 2011 June.

NEWS (Dec 21/2010): Interviewed by "Toronto Star" - The amazing things music does to your mind"
http://www.thestar.com/news/insight/article/909939--the-amazing-things-

NEWS (Nov 13/2010): My talk at Society for Neuroscience 2010 meeting (Nov 15, "Neuromagnetic oscillation in musical meter and beat processing") will be featured as "Hot Topic" at the conference.

NEWS (Nov 1/2010): I will be giving a Grand Neurology Round talk  at Toronto SickKids Hospital on Feb 16/2011.


Publications

Title Source (Journal/Book/Conference) Authors/Presenters Published On Type
The effect of music-support rehabilitation on motor, cognitive and psychosocial functions in chronic stroke. Ann New York Acad Sci Fujioka T, Ross B, Wright R, Chen JJ, Chen JL, Black SE, Stuss DT, Dawson D 1531627200 Journal Article
Neural coupling between contralesional motor and frontoparietal networks correlates with motor ability in individuals with chronic stroke J Neurol Sci Lam TK, Dawson DR, Honjo K, Ross B, Binns MA, Stuss DT, Black SE, Chen JJ, Levine BT, Fujioka T, Chen JL 1515992400 Journal Article
Neural correlates of intentional switching from ternary to binary meter in a musical hemiola pattern Frontiers in Psychology - Auditory Cognitive Neuroscience Fujioka T, Fidali B, Ross B 1413518400 Journal Article
Human cortical responses to slow and fast binaural beats reveal multiple mechanisms of binaural hearing. Journal of Neurophysiology Ross B, Miyazaki T, Thompson J, Jamali S, Fujioka T 1413345600 Journal Article
Neuromagnetic beta and gamma oscillations in the somatosensory cortex after music training in healthy older adults and a chronic stroke patient Clinical Neurophysiology Jamali S, Fujioka T, Ross B 1386651600 Journal Article
Simultaneous recording of brain responses indicating sensation and perception of changes in interaural phase differences Journal of the Acoustical Society of America Ross B, Fujioka T 1386565200 Presentation
Neuromagnetic beta-band oscillation for rhythmic processing induced by subjectively accented structure Journal of the Acoustical Society of America Fujioka T, Trainor LJ, Ross B 1386565200 Presentation
Beta and gamma oscillations as indicator for neuroplastic reorganization Ross B, Jamali S, Fujioka T 1366171200 Presentation
Sound envelope encoding in the auditory cortex revealed by neuromagnetic responses in the theta to gamma frequency bands Brain Research Miyazaki T, Thompson J, Fujioka T, Ross B 1360299600 Journal Article
Changes in neuromagnetic beta-band oscillation after music-supported stroke rehabilitation Annals of the New York Academy of Sciences Fujioka T, Ween JE, Jamali S, Stuss DT, Ross B 1334721600 Journal Article
Internalized timing of isochronous sounds is represented in neuromagnetic beta oscillations The Journal of Neuroscience Fujioka T, Trainor L, Large EW, Ross B 1328072400 Journal Article
Interference in dichotic listening: the effect of contralateral noise on oscillatory brain networks European Journal of Neuroscience Ross B, Miyazaki T, Fujioka T 1323925200 Journal Article
The effect of stimulus rate and metric subdivision on rhythmic music perception Music Perception Zendel B, Fujioka T, Ross B 1304136000 Journal Article
Human gamma band oscillations at the interface between sensation and conscious cognition 18TH ANNUAL MEETING OF THE COGNITIVE NEUROSCIENCE SOCIETY Ross B, Miyazaki T, Fujioka T 1303963200 Presentation
Gamma-band synchronization in the temporal lobe indexes metronome timing and its subdivision Fujioka T, Trainor L, Large E, Ross B 1303790400 Presentation
Neuromagnetic oscillation in musical meter and beat processing FUJIOKA T, ZENDEL B, ROSS B 1289624400 Presentation
Development of auditory-specific brain rhythm in infants European Jounal of Neuroscience Fujioka T, Mourad N, Trainor LJ 1288238400 Journal Article
Comparison of artifact correction methods for infant EEG applied to extraction of event-related potential signals Clinical Neurophysiology Fujioka T, Mourad N, He C, Trainor L 1277870400 Journal Article
Plastic change of neuromagnetic responses in auditory cortices over the course of music-supported motor rehabilitation program Fujioka T, Jamali S, Ween JE, Stuss D, Ross B 1276142400 Presentation
Neuromagnetic sensory evoked response as a biomarker of cortical reorganization during stroke recovery Jamali S, Ross B, Ween EJ, Stuss DT, Fujioka T 1275883200 Presentation
Why music moves us: Parallel motor networks in beta and high-gamma neuromagnetic oscillation actived according to the tempo of regularly repeating sounds. Fujioka T, Trainor L, Large E, Ross B 1271476800 Presentation
Endogenous neuromagnetic activity for mental hierarchy of timing Journal of Neuroscience Fujioka T, Zendel B, Ross B 1267592400 Journal Article
Neural representation of transposed melody in infants at 6 months of age Annals of the New York Academy of Sciences Tew S, Fujioka T, He C, Trainor L 1266469200 Journal Article
The effect of metre on accuracy and consistency of auditory motor synchronization Zendel BR, Fujioka T, Ross B 1249272000 Presentation
Beta and gamma rhythms in human auditory cortex during musical beat processing Annals of the New York Academy of Science Fujioka T, Trainor LJ, Large EW, Ross B 1246507200 Journal Article
Music-supported training of motor function: A neuroscience driven approach to stroke rehabilitation Interprofessional Rounds Ross B, Fujioka T 1236916800 Presentation
Domain-specific and domain-general effects of musical experience in young children Neuroscience of Music, Montreal 2008 Trainor LJ, Corrigall K, Fujioka T 1212897600 Presentation
Auditory processing indexed by stimulus-induced alpha desynchronization in children. International Journal of Psychopysiology Fujioka T, Ross B 1209614400 Journal Article
Aging and musical expertise on melodic encoding in auditory cortex Cognitive Neuroscience Society Fujioka T, Trainor LJ, Picton TW, Ross B 1208059200 Presentation
Simultaneous pitches are encoded separately in auditory cortex: an MMNm study. Neuroreport Fujioka T, Trainor LJ, Ross B 1202792400 Journal Article
Thinking in two vs. three beats: metric structure is represented in multiple cortical areas in skilled musicians International Conference on Biomagnetism Fujioka T, Zendel B, Ross B 1202187600 Presentation
Metric interpretation modulates the auditory evoked response The Neurosciences and Music III Zendel B, Fujioka T, Ross B 1202187600 Presentation
Metric interpretation modulates the auditory evoked response Cognitive Neuroscience Society Fujioka T, Zendel B, Ross B 1199163600 Presentation
Dynamics of thalamocortical circuits for sound processing revealed by magnetoencephalography 156th Meeting of the Acoustical Society of America Ross B, Fujioka T 1199163600 Presentation
Time courses of cortical beta and gamma-band activity during listening to metronome sounds in different tempi 156th Meeting of the Acoustical Society of America Fujioka T, Large E, Trainor L, Ross B 1199163600 Presentation
Aging in binaural hearing begins in mid-life: Evidence from cortical auditory-evoked responses to changes in interaural phase Journal of Neuroscience Ross B, Fujioka T, Tremblay KL, Picton TW 1192593600 Journal Article
Musical training effects and development in brain across life span Rotman Rounds Fujioka T 1165813200 Presentation
One year of musical training affects development of auditory cortical-evoked fields in young children Brain Fujioka T, Ross B, Kakigi R, Pantev C, Trainor LJ 1159675200 Journal Article
Cortical oscillations related to processing congruent and incongruent grapheme-phoneme pairs Neuroscience Letters Herdman AT, Fujioka T, Chau W, Ross B, Pantev C, Picton TW 1147665600 Journal Article
Automatic encoding of polyphonic melodies in musicians and nonmusicians Journal of Cognitive Neuroscience Fujioka T, Trainor LJ, Ross B, Kakigi R, Pantev C 1104555600 Journal Article
Combining Multiple Sessions MEG Data Organization for Human Brain Mapping Chau W, Fujioka T, Ross B 1104555600 Presentation
Cortical oscillations modulated by congruent and incongruent audiovisual stimuli Neurology and Clinical Neurophysiology Herdman AT, Fujioka T, Chau W, Ross B, Pantev C, Picton TW 1101790800 Journal Article
Musical training enhances automatic encoding of melodic contour and interval structure Journal of Cognitive Neuroscience Fujioka T, Trainor LJ, Ross B, Kakigi R, Pantev C 1088654400 Journal Article
Auditory memory trace encodes polyphonic melody 14th International Conference on Biomagnetism Fujioka T, Trainor LJ, Ross B, Kakigi R, Picton TW, Pantev C 1072933200 Presentation
Cortical oscillations modulated by congruent and incongruent audiovisual stimuli 14th International Conference on Biomagnetism Herdman AT, Fujioka T, Chau W, Ross B, Pantev C, Picton TW 1072933200 Presentation
Tonotopic representation of missing fundamental complex sounds in the human auditory cortex European Journal of Neuroscience Fujioka T, Ross B, Okamoto H, Takeshima Y, Kakigi R, Pantev C 1057982400 Journal Article
Music and learning-induced cortical plasticity Annals of the New York Academy of Sciences Pantev C, Ross B, Fujioka T, Trainor LJ, Schulte M, Schulz M 1041397200 Book Chapter

Academic Appointments

  • 2007–2010: Post Doctoral Fellow, Rotman Research Institute, Baycrest
  • 2010–Present: Scientific Associate, Rotman Research Institute, Baycrest

Reviewership

Consulting

  • Neuroscience letters
  • Neuroscience Seminars
  • Cognitive Brain Research
  • Journal of Cognitive Neuroscience
  • Journal of Neuroscience
  • PLosOne
  • Neurospsychology
  • Brain and Cognition
  • Clinical Neurophysiology
  • Journal of Acoustical Society of America
  • Ear and Hearing
  • Progress of Neurobiology
  • Review of Educational Research
  • Psychology of Music
  • Cerebral Cortex
  • Neuropsychology
  • BMC Neuroscience

Distinctions and Awards

  • 2004: Fellowship Award, Canadian Institutes of Health Research

Research Projects

External

  • 2010–2011: Cortical oscillation in processing of consonant and dissonant musical chords
    Collaborators: Dr. Laurel Trainor
    Institutions: Rotman Research Institute, Toronto, Canada

    Sponsors: CIHR Research Grant

    Investigating gamma-band rhythmic neural activities that might be related to multiple periodic sound (i.e., musical chords) perception using MEG (magnetoencephalograph)
  • 2010–2011: Mistuned harmonic component promotes sequential grouping on local pitch perception indexed by MEG
    Collaborators: Dr. Bernhard Ross, Dr. Claude Alain
    Institutions: Rotman Research Institute, Toronto, Canada

    Sponsors: CIHR

    -Investigate auditory evoked magnetic fields to examine how local pitch and global pitch interact with each other

Contact

The Rotman Research Institute
Baycrest
3560 Bathurst Street, 920
Toronto, Ontario,
Canada M6A 2E1 Phone: 416-785-2500 x3413 Email: tfujioka@rotman-baycrest.on.ca Fax: 416-785-2862