Regina Jokel

Dr. Regina Jokel, PhD

Associate Professor Department of Speech-Language Pathology, University of Toronto

Research Themes: Alzheimer's & Related Dementias, Aging & Brain Health

Research Techniques: Patient-based research, Intervention research, TMS, tDCS

Research Focus

My curernt research focuses on (1) non-invasive interventions for adults with primary progressive aphasia, a neurodegenerative disorder that deprives people of their ability to communicate, (2) utilization of digital technology for the purpose of diagnosis, intervention, and improvement in quality of life in aging and dementia, (3) signs of dementia in written and spoken language through computational analysis of online samples.

My current work is supported by the Ontario Brain Institute, Brain Canada, Alzheimer's Association, CIHR-NSERC, Age-Well, e-CAMPUS,  Centre for Aging and Brain Health Innovation, and Canadian Consortium on Neurodegeneration in Aging.

Publications

Title Source (Journal/Book/Conference) Authors/Presenters Published On Type
Language-related electro-physiological abnormalities in primary progressive aphasia NeuroImage: Clinical Kielar, Deschamps, Jokel, R, Meltzer 1564632000 Journal Article
Slowing is slowing: Delayed neural responses to words are linked to abnormally slow resting state activity in primary progressive aphasia Neuropsychologia Kielar, Shah-Basak, Deschamps, Jokel, Meltzer 1561694400 Journal Article
Rationale and protocol of the ENGAGE study: A double-blind randomized controlled preference trial using a comprehensive cohort design to measure the effect of a cognitive and leisure-based intervention in older adults with a memory complaint Trials Belleville S, Moussard A, Ansaldo AI, Belchoir P, Bherer L, Bier N, Bohbot VD, Bruneau MA, Cuddy LL, Gilbert B, Jokel R, Mahalingam K, McGilton K, Murphy KJ, Naglie G, Rochon E, Troyer AK, Anderson ND 1560139200 Journal Article
Rationale and protocol of the ENGAGE study: a double-blind randomized controlled preference trial using a comprehensive cohort design to measure the effect of a cognitive and leisure-based intervention in older adults with a memory complaint. Trials Belleville S, Moussard A, Ansaldo AI, Belchior P, Bherer L, Bier N, Bohbot VD, Bruneau MA, Cuddy LL, Gilbert B, Jokel R, Mahalingam K, McGilton K, Murphy KJ, Naglie G, Rochon E, Troyer AK, Anderson ND 1558497600 Journal Article
Language in amnestic mild cognitive impairment and Alzheimer's disease: Quantitative or qualitative differences? Dementia and Geriatric Cognitive Disorders Jokel, Seixas Lima, Fernandez, Murphy 1556424000 Journal Article
Bilingualism in primary progressive aphasia: A retrospective study on clinical and language characteristics Alzheimer Disease and Associated Disorders Costa, Jokel, Villarejo, Domoto-Reiley, Reetz, Machado 1551330000 Journal Article
SafeHome app: Design and usability of digital application to promote physical safety to persons living with dementia IEEEXplore Peisachovich, Apple, Sinclar, Jokel, DaSilva, Soroor 1530158400 Journal Article
Abnormal language-related oscillatory responses in primary progressive aphasia NeuroImage. Clinical Kielar A, Deschamps T, Jokel R, Meltzer JA 1514782800 Journal Article
Spontaneous oscillatory markers of cognitive status in two forms of dementia Human brain mapping Shah-Basak PP, Kielar A, Deschamps T, Verhoeff NP, Jokel R, Meltzer J 1514782800 Journal Article
The ENGAGE program: Combining cognitive training with engaging leisure activities Alzheimer's and Dementia Belleville, Anderson, Ansaldo Jokel, R, et al 1504238400 Journal Article
Intervention for primary progressive aphasia for clients and their spouses: Who comes first? Journal of Communication Disorders Jokel, R, Meltzer, Jet al 1498622400 Journal Article
Behavioral and neuroimaging changes after naming therapy for semantic variant PPA Neuropsychologia Jokel R, Kieler A, Anderson ND, Black SE, Rochon E, Freedman M, Tang-Wai D, Graham S 1473307200 Journal Article
Functional reorganization of language networks for semantics and syntax in chronic stroke: Evidence from MEG. Human Brain Mapping Kielar A, Deschamps T, Jokel R, Meltzer JA 1472702400 Journal Article
Behavioural and neuroimaging changes after therapy for semantic variant PPA Neuropsychologia Jokel, R, Kielar, Anderson et al 1470024000 Journal Article
When a duck is not a duck Aphasiology Jokel, R, Wolf, U 1470024000 Journal Article
When a duck is not a duck: Non-organic basis for aphasia and dementia Aphasiology Jokel, R, Wolf, U 1467086400 Journal Article
Identifying dysfunctional cortex: Dissociable effects of stroke and aging on resting state dynamics in MEG and fMRI. Front Aging Neurosci Kielar A, Deschamps T, Chu RK, Jokel R, Khatamian YB, Chen JJ, Meltzer JA 1456981200 Journal Article
Word retrieval therapies in primary progressive aphasia Aphasiology-Special Issue Jokel, Graham, Rochon 1403928000 Journal Article
Restoring semantic memory, word by word: Insights from semantic dementia Semantic Memory: Neurobiology, Disorders and Therapeutic Strategies for Improvement Jokel R, Anderson ND 1397966400 Book Chapter
Does Logopenic Progressive Aphasia Exist? Telehealth Geriatric Psychiatry Rounds Chow TW, Jokel R 1358485200 Presentation
P-Words That Go Together: PNFA, PT and slP City-wide Behavioural Neurology Videoconference Rounds Chow TW, Argent S, Jokel R 1357707600 Presentation
Quest for the best Neuropsychological Rehabilitation Jokel, Anderson 1340856000 Journal Article
Does Logopenic Progressive Aphasia Exist? City-wide Behavioural Neurology Videoconference Rounds Chow TW, Jokel R 1322024400 Presentation
Evidence for using MossTalk Words in PPA Evidence-Based Communication Assessment and Intervention Jokel, Rochon, Leonard, Cupit 1309233600 Journal Article
Neuroplasticity in dementia following language intervention: Illusion or possibility? Alzheimer's & Dementia Jokel R, Anderson N, Black S, Rochon E, Freedman M, Chow T, Tang-Wai D 1303617600 Abstract
Errorless learning of computer-generated words in a patient with semantic dementia Neuropsychological Rehabilitation Jokel R, Rochon E, Anderson ND 1262322000 Journal Article
Relearning lost vocabulary in nonfluent progressive aphasia with MossTalk Words® Aphasiology Jokel R, Cupit J, Rochon EA, Leonard C 1230786000 Journal Article
Mechanisms underlying naming impairments in post-stroke and progressive aphasia Dissertation Abstracts International: Section B: The Sciences and Engineering Jokel 1214625600 Technical Paper
Re-learning lost vocabulary in nonfluent progressive aphasia with MossTalk Words Aphasiology Jokel, Cupit, Rochon, Leonard 1214625600 Journal Article
Speech dysfluencies in adults with neurogenic stuttering associated with stroke and traumatic brain injury Journal of Medical Speech-Language Patholgy Jokel, DeNill, Sharpe 1183003200 Journal Article
Adult-onset neurogenic stuttering Clinical Management of Sensorimotor Speech Disorders De Nil LF, Rochon EA, Jokel R 1167627600 Book Chapter
Etiology, symptomatology, and treatment of neurogenic stuttering Stuttering and Related Disorders of Fluency De Nil LF, Jokel R, Rochon EA 1167627600 Book Chapter
Speech disfluencies in adults with acquired stuttering associated with stroke and traumatic brain injury Journal of Medical Speech-Language Pathology Jokel R, De Nil L, Sharpe K 1167627600 Journal Article
Treating anomia in semantic dementia: Improvement, maintenance or both? Neuropsychological Rehabilitation Jokel, Rochon, Leonard 1151467200 Journal Article
Treating anomia in semantic dementia: Improvement, maintenance, or both? Neuropsychological Rehabilitation Jokel R, Rochon EA, Leonard C 1136091600 Journal Article
Computer-based intervention for anomia in progressive aphasia Brain and Language Jokel R, Cupit J, Rochon E, Leonard C 1136091600 Journal Article
Computer-based treatment for anomia in nonfluent progressive aphasia Academy of Aphasia Meeting Jokel, R 1136091600 Presentation
Language in fronto-temporal dementia Baycrest Annual Conference for SLP Jokel R 1136091600 Presentation
The semantic-phonological model and progressive aphasia Brain and Language Jokel R, Rochon EA 1104555600 Journal Article
The semantic-phonological model and progressive aphasia Academy of Aphasia Meeting Jokel R 1104555600 Presentation
Language in neurodegenerative disorders Ontario Speech-Language Pathology and Audiology Association convention Jokel R 1104555600 Presentation
Mechanisms underlying naming impairments in progressive aphasia Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care Jokel R 1104555600 Presentation
Sentence comprehension in semantic dementia: A longitudinal case study Cognitive Neuropsychology Rochon E, Kavé G, Cupit J, Jokel R, Winocur G 1072933200 Journal Article
Testing predictions of the interactive activation model in recovery from aphasia after treatment Brain and Cognition Jokel R, Rochon EA 1072933200 Journal Article
Application of the Interactive Activation Model of Lexical Retrieval to Naming Impairments in Nonfluent Progressive Aphasia Australian Conference on Cognitive Neuropsychology and Cognitive Neuropsychiatry Jokel R 1072933200 Presentation
Language Higher Cognition course at the Graduate Department of Psychology, University of Toronto Jokel R 1072933200 Presentation
How orthography helped phonology: A case of anomia treatment Aphasia Interest Group Teleconference Jokel R 1072933200 Presentation
Aphasia Therapy in Neurological Disease Behavioral Neurology Clinic Day Jokel R 1072933200 Presentation
Treatment for Aphasia After Brain Damage Behavioral Neurology Clinic Day Jokel R 1072933200 Presentation
Changes in error patterns pre- and post-treatmentin view of the interactive activation model of lexical retrieval Brain and Language Jokel R, Rochon EA 1041397200 Journal Article
Changes in Error Patterns Pre and Post-Treatment in View of the Interactive Activation Model of Lexical Retrieval Academy of Aphasia Jokel R 1041397200 Presentation
Testing Predictions of the Interactive Activation Model In Recovery From Aphasia After Treatment TENNET XIV Conference Jokel R 1041397200 Presentation
Therapy for anomia in semantic dementia BRAIN AND COGNITION Jokel R, Rochon EA, Leonard C 1009861200 Abstract
Semantic dementia and Alzheimer's disease: Clinical differences in speech-language pathology Perspectives on Gerontology Jokel R, Rochon EA 1009861200 Journal Article
Acquired Stuttering in Adults 6th Oxford Dysfluency Conference Jokel R 1009861200 Presentation
Acquired stuttering in adults Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care Jokel R 1009861200 Presentation
Treatment for anomia in semantic dementia 11th Annual Rotman Research Institute Conference: Dementia - Biological and Clinical Advances Jokel R 984891600 Presentation
From Theory to Practice and Back IALP Conference Jokel R 978325200 Presentation
Neuropsychology seminar series Annual series of lectures on language assessment and treatment to doctoral residents in the Psychology Department, Baycrest Centre for Geriatric Care and University of Toronto joint program Jokel R 946702800 Presentation
Mirror reading, writing and backward speech in a woman with head injury: A case of conversion disorder Aphasiology Jokel, Conn 930542400 Journal Article
Case Study: Mirror reading, writing and backward speech in a woman with a head injury: a case of conversion disorder Aphasiology Jokel R, Conn D 915166800 Journal Article
Surface dyslexia in non-fluent progressive aphasia Brain & Language Watt, Jokel, Behrmann 867470400 Journal Article
Surface dyslexia in nonfluent progressive aphasia Brain and Language Watt S, Jokel R, Behrmann M 852094800 Journal Article
Quest for the Best: Effects of Errorless and Active Encoding on Word Re-learning in Semantic Dementia Neuropsychological Rehabilitation: Special Issue on Errorless Learning Jokel, R, Anderson, N -28800 Journal Article
Rehabilitation of Language in Fluent Progressive Aphasia Lodz Studies of Language: Cognitive Processes in Language Jokel, R -28800 Book Chapter
Evidence for Using MossTalk Wordsin Progressive Aphasia Evidence-Based Communication Assessment and Intervention Jokel, R, Rochon, E, Leonard, C, Cupit, J -28800 Journal Article
Nonfluent Progressive Aphasia without agrammatism or apraxia of speech Procedia-Social and Behavioural Sciences Graham, N, Tang-Wai, D, Black, S, Leonard, C, Jokel, R, Schwindt, G, Rochon, E -28800 Abstract
Neuroplasticity in Dementia Following Language Rehabilitation: Illusion or Possibility? Alzheimer's and Dementia Jokel, R, Anderson, N, Black, S, Rochon, E, Freedman, M, Chow, T, Tang-Wai, D, -28800 Abstract
Successful treatment for anomia associated with fronto-tempral dementias Jokel, R, -28800 Presentation
Nonfluent progressive aphasia without agrammatism or apraxia of speech Rochon, E, Graham, N, Jokel, R -28800 Presentation
Neuroplasticity in Dementia following language intervention Jokel, R -28800 Presentation
Effectiveness of semantic versus phonological cues in semantic dementia Jokel, R -28800 Presentation
Language processing in semantic dementia Jokel, R -28800 Presentation
Comprehension, Maintenance, and Generalization after Treatment for Anomia in Semantic Dementia Jokel, R -28800 Presentation
Application of errorless learning to anomia in semantic dementia Jokel, R -28800 Presentation

Education

  • 1991: Master of Health Science, Speech-Language Pathology, University of Toronto Toronto, Ontario, Canada
  • 2007: PhD, Department of Speech-Language Pathology, University of Toronto Toronto, Ontario, Canada

Academic Appointments

  • 2008–Present: Associate Professor, Department of Speech-Language Pathology, University of Toronto, Toronto, Ontario, Canada
  • 1991–Present: Speech-Language Pathologist, Sam and Ida Ross Memory Clinic, Baycrest Hospital, Toronto, Ontario, Canada

Professional Affiliations

  • 1992–Present: Certified Member, American Speech-Language-Hearing Association
  • 2012–Present: Founding Member, International Society for Fronto-Temporal Dementias
  • 1994–Present: Certified Member, College of Audiologists and Speech-Language Pathologists of Ontario
  • 2011–Present: Member, Alzheimers Association International Society to Advance Alzheimers Research and Treatment (ISTAART)

Reviewership

Consulting

  • Journal of Communication Disorders
  • Aphasiology
  • Neuropsychological Rehabilitation
  • Journal of Fluency Disorders

Membership

  • Baycrest Ethics Board
  • 1991–Present: Member of the College of Audiologists and Speech-Language Pathologists of Ontario
  • 1991–Present: Certified member of the American Speech-Language-Hearing Association
  • 2010–Present: University of Toronto Research Ethics Board

Distinctions and Awards

  • 2018: Nominated for Weston Brain Institute Outstanding Achievement Award, Weston Brain Institute
  • 2016: Distinguished Service Award, University of Toronto
  • 2016: Excellence in Teamwork, Baycrest Health Sciences
  • 2010: Age Plus Award for publication on aging, Canadian Institutes of Health Research
  • 2006: Post-Doctoral Fellowship (2 years, second year declined), Kunin-Lunenfeld Applied Resaerch Unit
  • 2006: Post-Doctoral Fellowship (2 years), Canadian Institutes of Health Research
  • 2005: Ontario Graduate Scholarship (declined)
  • 2003: Doctoral Fellowship (2 years), Canadian Institutes of Health Research
  • 2003: Award for a top-ranked candidate in Institute of Aging 2002 competition, Canadian Institutes of Health Research
  • 2003: Ontario Graduate Scholarship (declined)
  • 2002: Open Fellowship Award (declined), University of Toronto
  • 2002: Ontario Graduate Scholarship in Science and Technology Award
  • 2002: Toronto Rehabilitation Institute Scholarship
  • 2002: Ontario Graduate Scholarship
  • 2001: Ontario Graduate Scholarship in Science and Technology Award
  • 2001: Shore & Gorman Award, Baycrest Centre for Geriatric Care
  • 2001: D.J. MacGeachy Memorial Scholarship, University of Toronto
  • 2000: Shore and Gorman Award, Baycrest Centre for Geriatric Care
  • 2000: Open Fellowship Award, University of Toronto
  • 2000: D.J. MacGeachy Memorial Scholarship, University of Toronto

Research Projects

External

  • 2010: Errorless re-learning in semantic dementia
    Collaborators: Anderson, N.

    Sponsors: CIHR

  • 2009–2011: Slowing language decline in progressive language disorders: A treatment and neuroimaging study
    Collaborators: Anderson, N., Black, S., Rochon, E., DeNil, L., Freedman, M, Graham, S., Tang-wai, D.

    Sponsors: CIHR, 81,530 (CDN)

    Research Grant
  • 2009–2010: Natural language processing methods for the early detection of Alzheimer's disease in patients' online writing
    Collaborators: Hirst, G., Lancashire, I., Li, X.

    Sponsors: Google, 36,000 (US)

    Research Grant
  • 2003–2007: Mechanisms underlying naming impairments in post-stroke and progressive aphasia
    Collaborators: Rochon E

    Sponsors: CIHR

  • 2017–2018: Beyond Words... and Towards Digital Accessibility with SafeHome App
    Collaborators: Peisachovich, Appel, Sinclair, DaSilva

    Sponsors: Government of Ontario, 19,634

    Research Grant
  • 2018–2019: Words at Your Fingertips: Website for word finding in healthy aging
    Collaborators: Somji, Romeril, Ackerman, Piccini

    Sponsors: Centre for Aging and Brain Health Innovation, 49,500

    Research Grant
  • 2017–2020: Automatic Remote Screening of Speech Features Associated with Alzheimer's Disease
    Collaborators: Rudzicz

    Sponsors: CHRP, 440,265

    Research Grant
  • 2017–2019: Assessing Cognitive Ability Using Automated Assessment of Speech
    Collaborators: Rudzicz

    Sponsors: Age-WELL Research Grant

  • 2014–2018: Individually Optimized Brain Stimulation in Dementia
    Collaborators: Meltzer

    Sponsors: Ontario Brain Institute, 722,655

    Research Grant
  • 2016–2018: Preventing Language Decline in Dementia

    Sponsors: Brain Canada/Alzheimer Association, 85,392 (US $)

    Research Grant
  • 2019–2020: Feasibility of a comprehensive intervention program for clients with PPA and their caregivers
    Collaborators: Rochon, Lavoie, Tartaglia, Tang Wai
    Institutions: RRI, TWH

    Sponsors: Philanthropic funding, 40,000 (CAD)

    Research Grant

Curriculum Vitae

Contact

Rotman Research Institute
3560 Bathurst Street
North York, Ontario
M6A 2E1 Phone: (416) 785-2500 ext. 2074 Email: rjokel@research.baycrest.org