Yi Du

Dr. Yi Du, PhD

Postdoctoral Fellow Rotman Research Institute

Research Focus

My research focuses on the neural mechanisms underlying auditory scene analysis and speech perception in “cocktail-party” environment, with special emphasis on the interaction between auditory "what", "where" and "how" neural pathways which engages in encoding sound identity, spatial processing, and sensorimotor integration, respectively. I use a combination of neuroimaging techniques (e.g., MEG, ERP and fMRI) to investigate which, and how, different brain areas are recruited and modulated by attention and perceptual learning in processing speech identity and/or location. Also I am interested in how the auditory-motor areas, which are involved in speech production, contribute to speech perception in demanding circumstance and how this function is influenced by cognitive aging.


Title Source (Journal/Book/Conference) Authors/Presenters Published On Type
Listening under difficult conditions: An activation likelihood estimation meta-analysis Human brain mapping Alain C, Du Y, Bernstein LJ, Barten T, Banai K 1514782800 Journal Article
Increased activity in frontal motor cortex compensates impaired speech perception in older adults Nature communications Du Y, Buchsbaum BR, Grady CL, Alain C 1451624400 Journal Article
Recruitment of the speech motor system in adverse listening conditions The Journal of the Acoustical Society of America Alain C, Du Y 1429934400 Journal Article
Rapid Tuning of Auditory “What” and “Where” Pathways by Training Cerebral Cortex Du Y, He Y, Arnott SR, Ross B, Wu X, Li L, Alain C 1422766800 Journal Article
“What”, “Where” and Sensorimotor Integration in Speech Perception Montreal Neurological Institute, McGill University Du Y 1410148800 Presentation
Noise differentially impacts phoneme representations in the auditory and speech motor systems Proceedings of the National Academy of Sciences USA Du Y, Buchsbaum BR, Grady CL, Alain C 1399953600 Journal Article
The compensatory mechanism of auditory-motor integration in speech perception Cognitive Neuroscience Society Annual Meeting Du Y, Buchsbaum B, Grady C, Alain C 1365825600 Presentation
Perceived target-masker separation unmasks responses of lateral amygdala to the emotionally conditioned target sounds in awake rats Neuroscience Du Y, Wang Q, Zhang Y, Wu XH, Li L 1354770000 Journal Article
Feature-specific cortical plasticity after rapid perceptual learning during speech segregation Acoustical Society of America 2012 Hong Kong Conference Du Y, He Y, Wu XH, Li L, Alain C 1337140800 Presentation
Feature-specific cortical plasticity after rapid perceptual learning during speech segregation: a MEG study Journal of Acoustical Society of America Du Y, He Y, Wu X, Li L, Alain C 1333252800 Abstract
Auditory frequency-following response: The neurophysiological marker for studying the “cocktail-party problem” Neuroscience and Biobehavioral Reviews Du Y, Kong LZ, Wang Q, Wu XH, Li L 1320555600 Journal Article
Differentially organized top-down modulation of prepulse inhibition of startle Journal of Neuroscience Du Y, Wu XH, Li L 1316577600 Journal Article
Human auditory cortex activity shows additive effects of spectral and spatial cues during speech segregation Cerebral Cortex Du Y, He Y, Ross B, Bardouille T, Wu X, Li L, Alain C 1298955600 Journal Article
Additive Effects of Spectral and Spatial Cues in Human Auditory Cortex during Speech Segregation 16th Annual Meeting of the Organization for Human Brain Mapping Du Y, He Y, Bardouille T, Ross B, Wu X, Li L, Alain C 1275796800 Presentation
Emotional learning enhances stimulus-specific top-down modulation of sensorimotor gating in socially reared rats but not isolation-reared rats Behavioural Brain Research Du Y, Wu XH, Li L 1263963600 Journal Article
Two crossed axonal projections contribute to binaural unmasking of frequency-following responses in rat inferior colliculus European Journal of Neuroscience Du Y, Ma TF, Wang Q, Wu XH, Li L 1257051600 Journal Article
Top-down modulation of prepulse inhibition of the startle reflex in humans and rats Neuroscience and Biobehavioral Reviews Li L, Du Y, Li NX, Wu XH, Wu YH 1251864000 Journal Article
Precedence effect-induced enhancement of prepulse inhibition in socially reared but not isolation-reared rats Cognitive, Affective, and Behavioral Neuroscience Du Y, Li J, Wu XH, Li L 1237608000 Journal Article
Binaural unmasking of frequency-following responses in rat amygdala Journal of Neurophysiology Du Y, Huang Q, Wu XH, Galbraith GC, Li L 1237089600 Journal Article
Ultrasonic evoked responses in rat cochlear nucleus Brain Research Du Y, Ping JL, Li NX, Wu XH, Li L, Galbraith G 1191384000 Journal Article


  • 2011: PhD, Psychology, Peking University China
  • 2005: BMSc, Medical Science, Peking University Medical Science Center China

Academic Appointments

  • 2012–Present: Postdoctoral Fellow, Rotman Research Institute

Research Groups

  • 2012:

Distinctions and Awards

  • 2011: Excellent Doctoral Dissertation & Graduate Award, Peking University
  • 2011: Excellent Conference Paper, Chinese Neuroscience Society
  • 2010: Excellent Conference Paper, Chinese Psychophysiology Society
  • 2010: Award of Excellent Paper, Academician Shi Qingyun Fund from Peking University
  • 2009: Innovation Award, Peking University
  • 2005: Excellent Graduate Award, Peking University and Beijing Education Bureau


Rotman Research Institute
3560 Bathurst Street
Toronto, ON
M6A 2E1
Canada Phone: 416-785-2500 x2173 Email: ydu@research.baycrest.org Fax: 416-785-2862