Stephen Strother

Dr. Stephen Strother

Senior Scientist Rotman Research Institute, Baycrest

Professor Department of Medical Biophysics, University of Toronto

Research Focus

My research is directed at developing and testing a set of optimal experimental planning, standardization and analysis tools for neuroimaging researchers that are coupled with state-of-the-art neuroimaging research databases. The overall goal is to yield new insights into human mental functions, how they are changed with normal aging, and compromised by damage and disease across the lifespan. We pursue this by merging and formally optimizing multi-modality neuroimaging (e.g., positron emission tomography, structural and functional magnetic resonance imaging, electroencephalography) and meta-data using machine learning and modern biostatistical techniques.

A major focus of this work involves multi-institutional support of the Brain-CODE data repository and analytics infrastructure at HPCVL supported by the Ontario Brain Institute (OBI). In particular we are co-investigators within the multi-institutional, independent disease programs in neurodegeneration and depression funded by OBI, and the multi-institutional stroke program of the Canadian Partnership for Stroke Recovery.

My goals require optimization of the experimental designs, data-analysis algorithms and associated software tools being developed for cognitive neuroscience and clinical neuroimaging as a function of age and disease, in the so-called "processing pipeline". Processing pipeline choices in neuroimaging pose a range of critical issues, particularly which tools/packages to use for a particular experiment. However, there is growing evidence that new insights into human brain function may be obscured by poor choices in the image-processing pipeline particularly as a function of age and disease. We are focusing on using HPC to optimize pipelines for measuring brain networks with multivariate machine learning models and resampling techniques from the field of statistical learning theory. In particular we are developing a quantitative, optimization framework called NPAIRS that focuses on using prediction and reproducibility metrics. An initial software package is distributed as an opensource Java package, and several other packages are under development and undergoing evaluation for commercialization.

Publications

Title Source (Journal/Book/Conference) Authors/Presenters Published On Type
The association between cerebrovascular reactivity and resting-state fMRI functional connectivity in healthy adults: The influence of basal carbon dioxide NeuroImage Golestani AM, Kwinta JB, Strother SC, Khatamian YB, Chen JJ 1455512400 Journal Article
An Automated, Adaptive Framework for Optimizing Preprocessing Pipelines in Task-Based Functional MRI PLoS One Churchill NW, Spring R, Afshin-Pour B, Dong F, Strother SC 1436500800 Journal Article
The Negative Effects of Common Image Processing and Analysis Pipeline Choices Annual Conference Organization for Human Brain Mapping Strother SC 1433476800 Presentation
How many separable sources? Model selection in ICA PLoS One Woods RP, Hansen LK, Strother SC 1427342400 Journal Article
A computerized tablet with visual feedback of hand position for functional magnetic resonance imaging Frontiers in Human Neuroscience Karimpoor M, Tam F, Strother SC, Fischer CE, Schweizer TA, Graham SJ 1427256000 Journal Article
Comparison of artifact removal methods in simultaneous EEG-fMRI J. Neuroscience Methods Shams N, Alain C, Strother SC 1424754000 Journal Article
Neuroinformatics pipelines in the BrainCODE neuroscience data centre Neuroscience Association for Undergraduate Students (NAUS) Strother SC 1417237200 Presentation
Big Data in Neuroscience Galbraith Society Meeting Strother SC 1417237200 Presentation
A hybrid NPAIRS (LDA+gCCA) model for fMRI data classification and visualisation IEEE Trans. Med. Imaging Afshin-Pour B, Grady C, Strother SC 1416978000 Journal Article
Stability and Reproducibility in fMRI Analysis. In: Practical Applications of Sparse Modeling Neural Information Processing Series Strother SC, Rasmussen PM, Churchill NW, Hansen LK 1414555200 Book Chapter
What’s the Big Deal about Big Data 25th Anniversary of Rotman Research Institute Strother SC 1405569600 Presentation
Brain Networks and Behaviour in Functional Magnetic Resonance Studies Medical Biophysics Summer Student Rounds Strother SC 1404273600 Presentation
The functional connectivity landscape of the human brain PLoS One Mišić B, Fatima Z, Askren MK, Buschkuehl M, Churchill N, Cimprich B, Deldin PJ, Jaeggi SM, Jung MS, Korostil, M, Kross E, Krpan KM, Petlier S, Reuter-Lorenz PA, Strother SC, Jonides J, McIntosh AR, Berman MG 1400644800 Journal Article
Pattern classification of fMRI data: applications for analysis of spatially distributed cortical networks Neuroimage Yourganov G, Schmah T, Churchill NW, Berman MG, Grady CL, Strother SC 1396584000 Journal Article
Longitudinal Changes in Brain Volume Following Remote Repetitive TBI: Evidence from Retired Professional and Semi-Professional Hockey Players Esopenko C, Pangelinan M, Bacopulos A, Chow T, McIntosh AR, Paus T, Strother S, Levine B 1395979200 Presentation
Comparing within-subject classification and regularization methods in fMRI for large and small sample sizes Human Brain Mapping Churchill N, Yourganov G, Strother SC 1395028800 Journal Article
Multivariate Statistical Analysis in Psychology and Neuroscience Rotman Conference Workshop Strother SC, Abdi H 1393736400 Presentation
Evaluation of multivariate functional connectivity techniques for group analysis of resting state data sets Neuroimage Afshin-Pour B, Grady C, Strother SC 1392440400 Journal Article
Tracking and Predicting Stroke Recovery with Neuroimaging Metrics of Brain Complexity Sunnybrook Rounds Strother SC 1383364800 Presentation
Simultanous EEG-fMRI recording of passive sensory processing Shams N, Alain C, Strother S 1371096000 Presentation
Neuroinformatics in BrainCODE for BOLD fMRI and Brain Networks Strother SC 1370145600 Presentation
PHYCAA+: An Optimized, Adaptive Procedure for Measuring and Controlling Physiological Noise in BOLD fMRI Neuroimage Churchill N, and Strother SC 1369972800 Journal Article
Neuroimaging during a Working Memory Task in Remote Traumatic Brain Injury: Evidence from NHL Alumni Esopenko C, Kumar PK, Alain C, Chow TW, McIntosh AR, Strother S, Levine B 1365825600 Presentation
Dimensionality of brain networks linked to life-long individual differences in self-control Nature Communications Berman MG, Yourganov G, Askren MK, Ayduk O, Casey BJ, Gotlib IH, Kross E, McIntosh AR, Strother S, Wilson NL, Zavas V, Mischel W, Shoda Y, Jonides J 1365134400 Journal Article
The Interaction between Traumatic Brain Injury and Aging: Evidence from NHL Alumni Esopenko C, Kumar PK, Alain C, Chow TW, McIntosh AR, Strother S, Levine B 1360126800 Presentation
Model sparsity and brain pattern interpretation of classification models in neuroimaging Pattern Recognition Rasmussen PM, Hansen LK, Madsen KH, Churchill N, Strother SC 1354510800 Journal Article
Brain networks linked to life-long individual differences in self-control Nature Communications Berman MG, Yourganov G, Askren MK, Ayduk O, Casey BJ, Gotlib IH, Kross E, McIntosh AR, Strother SC, Wilson NL, Zayas V, Mischel W, Shoda Y, Jonides J 1354510800 Journal Article
The Ugly, the Bad and the Good of Predictive Modeling for Functional Brain Networks Rotman Rounds Strother SC 1352091600 Presentation
The Impact of Different Multivariate Analysis Techniques on Resting State Network Detection Neuroimaging Rounds, Toronto Western Hospital Strother SC 1352091600 Presentation
Abnormal network connectivity in frontotemporal dementia: Evidence for prefrontal isolation Cortex Farb NA, Grady CL, Strother S, Tang-Wai DF, Masellis M, Black S, Freedman M, Pollock BG, Campbell KL, Hasher L, Chow TW 1348459200 Journal Article
Multi-dataset analytics PhD Course: The Emotional Brain, Centre for Integrated and Molecular Brain Imaging Strother SC 1346817600 Presentation
Problems of Functional Imaging Pipelines and their Optimization Ecole Polytechnique Federale de Lausanne Strother SC 1344139200 Presentation
The Ugly, the Bad and the Good of Predictive Modeling for Functional Brain Networks. University of Geneva Strother SC 1344139200 Presentation
The Impact of Different Multivariate Analysis Techniques on Resting State Network Detection. 3rd Biennial Resting State Meeting Strother SC 1344139200 Presentation
Brain Networks and Behaviour in Functional MRI Studies Medical Biophysics Summer Student Rounds Strother SC 1341460800 Presentation
Mathematical Problems of Functional Imaging Pipelines and their Optimization MITACS Workshop on the Mathematics of Brain Imaging Strother SC 1341460800 Presentation
SPReD: The Stroke Patient Recovery Research Database INCF Canadian Neuroinformatics Workshop, CAN Satellite Strother SC 1336190400 Presentation
Structural Equation Modeling Educational course, Functional Connectivity, ISMRM Strother SC 1336190400 Presentation
Enhancing reproducibility of fMRI statistical maps using generalized canonical correlation analysis in NPAIRS framework NeuroImage Afshin-Pour B, Hossein-Zadeh G-A, Strother SC, Soltanian-Zadeh H 1335844800 Journal Article
The Stability of Behavioural PLS Results in Ill-Posed Neuroimaging Problems Proc. PLS-2012 Churchill N, Spring R, Kovacevic N, McIntosh R, Strother SC 1330750800 Journal Article
Optimizing Preprocessing and Analysis Pipelines for Single-Subject fMRI: 2. Interactions with ICA, PCA, Task Contrast and Inter-Subject Heterogeneity PLoS One Churchill NW, Yourganov G, Oder A, Tam F, Graham SJ, Strother SC 1330318800 Journal Article
Connecting Brain Networks and Behaviour in BOLD fMRI of Individual-Subjects. Neuroimaging Rounds, Toronto Western Hospital Strother SC 1328418000 Presentation
Neuroinformatics at the Rotman Research Institute Neurology Laboratory, USC Irvine Strother SC 1328418000 Presentation
Complex and magnitude-only preprocessing of 2D and 3D BOLD fMRI data at 7 Tesla Mag. Res. Medicine Barry RL, Strother SC, Gore JC 1313121600 Journal Article
PHYCAA: Data-Driven Measurement and Removal of Physiological Noise in BOLD fMRI NeuroImage Churchill N, Yourganov G, Spring R, Rasmussen P, Lee W, Ween J, Strother SC 1313121600 Journal Article
Connecting Brain Networks and Behaviour in BOLD fMRI of Individual Subjects Brain Connectivity Day Symposium on Neural Networks of the Brain, Hospital for Sick Children Strother SC 1307160000 Presentation
Optimizing preprocessing and analysis pipelines for single-subject fMRI. I. Standard temporal motion and physiological noise correction methods. Human Brain Mapping Churchill NW, Oder A, Abdi H, Tam F, Lee W, Thomas C, Ween JE, Graham SJ, Strother SC 1306814400 Journal Article
Dimensionality estimation for optimal detection of functional networks in BOLD fMRI data. NeuroImage Yourganov G, Chen X, Lukic AS, Grady CL, Small SL, Wernick MN, Strother SC 1305432000 Journal Article
Multi-Set Data Analysis Educational workshop on Molecular and Functional Brain Imaging Strother SC 1304568000 Presentation
Prediction, and Activation-Pattern Sparsity and Stability in fMRI analysis Plenary Lecture, IEEE Int. Workshop on Pattern Recognition in NeuroImaging Strother SC 1304568000 Presentation
Post processing: What are the current methods Educational course, Functional and Anatomic Data Analysis: Principles and Practicalities, ISMRM Strother SC 1304568000 Presentation
A mutual information-based metric for evaluation of fMRI data-processing approaches. Human Brain Mapping Afshin-Pour B, Soltanian-Zadeh H, Hossein-Zadeh GA, Grady CL, Strother SC 1301630400 Journal Article
Data-driven optimization and evaluation of 2D EPI and 3D PRESTO for BOLD fMRI at 7 Tesla: I. Focal coverage. NeuroImage Barry RL, Strother SC, Gatenby JC, Gore JC 1301630400 Journal Article
Reproducible Pipelines, Statistical Parametric Maps and Strong Inference in fMRI NEUROIMAGE Strother SC 1299906000 Abstract
A new tablet for writing and drawing during functional MRI Human Brain Mapping Tam F, Churchill NW, Strother SC, Graham SJ 1296536400 Journal Article
Stability and reproducibility in fMRI analysis Neural Information Processing Systems’ Workshop on Practical Application of Sparse Modeling: Open Issues and New Directions Strother SC 1291525200 Presentation
The Structure of Functional Brain Connectivity Revealed by "Mind Reading” Preeproducibilty Metrics in the NPAIRS framework.diction and R New Horizons in Human Brain Imaging: A focus on Brain Networks and Connectivity Strother SC 1291525200 Presentation
Neuroinformatics in the Strother Laboratory Rotman Rounds Strother SC 1291438800 Presentation
Driven Evaluation and Optimization of Acquisition Strategies for Ultra-High-Field Functional MRI at 7 Tesla BSEC 2010 Annual ORNL Biomedical Science & Engineering Conference: Biomedical Research and Analysis in Neuroscience Barry RL, Strother SC, Gatenby G, Gore JC 1291352400 Technical Paper
Data warehousing methods and processing infrastructure for brain recovery research Archives of Italian Biology Gee T, Kenny S, Price CJ, Seghier ML, Small SL, Leff AP, Pacurar A, Strother SC 1283313600 Journal Article
Functional connectivity metrics during stroke recovery Archives of Italian Biology Yourganov G, Schmah T, Small SL, Rasmussen PM, Strother SC 1283313600 Journal Article
Occupation attributes relate to location of atrophy in frontotemporal lobar degeneration Neuropsychologia Spreng RN, Rosen H, Strother S, Chow TW, Diehl-Schmid J, Freedman M, Graff-Radford N, Hodges J, Lipton A, Mendez M, Morelli S, Black SE, Miller BL, Levine B 1283140800 Journal Article
The NPAIRS Computational Statistics Framework for Data Analysis in Neuroimaging Invited Lecture, Brain Imaging Session, 19th Int. Conf. On Computational Statistics Strother SC 1280980800 Presentation
Olaf Paulson and the Predictive, Reproducible Brain Anniversary Symposium in Honour of the 70th Birthday of Prof. Olaf B. Paulson, Rigshospitalet Strother SC 1280980800 Presentation
Multivariate Analysis of the CIMBI Altanserin 5-HT2A Binding Potential Values Seminar Series, CIMBI Young Investigators Group, Copenhagen University Strother SC 1280980800 Presentation
The NPAIRS Computational Statistics Framework for Data Analysis in Neuroimaging Proc. 19th Int. Conf. on Computational Statistics: Refereed Keynote, Invited and Contributed Papers Strother SC, Oder A, Spring R, Grady C 1280635200 Technical Paper
Machine learning in medical imaging IEEE Signal Processing Magazine Wernick MN, Yang Y, Brankov JG, Yourganov G, Strother SC 1276488000 Journal Article
Better BOLD across the lifespan from children to the elderly Seminar, Lifespan Psychology Group, Max Planck Institute for Human Development Strother SC 1275710400 Presentation
Group specific optimisation of fMRI processing steps for child and adult data NeuroImage Evans JW, Todd RM, Taylor MJ, Strother SC 1267506000 Journal Article
Better BOLD across the lifespan from children to the elderly Seminar Series, Dept. Statistics, Columbia University Strother SC 1262667600 Presentation
Comparing classification methods for longitudinal fMRI studies. Neural Computation Schmah T, Yourganov G, Zemel RS, Hinton GE, Small SL, Strother SC 1262322000 Journal Article
Longitudinal cerebral blood flow changes during speech in hereditary ataxia. Brain and Language Sidtis JJ, Strother SC, Naoum A, Rottenberg DA, Gomez C 1262322000 Journal Article
A multivariate analysis of age-related differences in default mode and task-positive networks across multiple cognitive domains. Cerebral Cortex Grady CL, Protzner AB, Kovacevic N, Strother SC, Afshin-Pour B, Wojtowicz M, Anderson JA, Churchill N, McIntosh AR 1262322000 Journal Article
Better BOLD fMRI across the lifespan from children to the elderly Rotman Rounds Strother SC 1257742800 Presentation
Generative versus discriminative training of RBMs for classification of fMRI images Advances in Neural Information Processing Systems Schmah T, Hinton G, Zemel RS, Small SL, Strother SC 1257051600 Technical Paper
Reproducible pipelines, satistical parametric maps and strong inference in fMRI studies of cognitive aging Strother SC, Afshipour B, Yourganov G, Oder A, Grady C 1245297600 Presentation
How Close to Zero is the Estimated Zero in BOLD fMRI Analyses as a Function of Age and Task? NEUROIMAGE Afshinpour B, Anderson J, Churchill N, Kovacevic N, Grady C, Strother S 1245297600 Abstract
Optimizing Activation Detection with Better Dimensionality Estimation in BOLD fMRI NEUROIMAGE Yourganov G, Lukic A, Grady C, Wernick M, Strother S 1245297600 Abstract
Functional connectivity reveals inefficient working memory systems in post-traumatic stress disorder Psychiatry Research: Neuroimaging Shaw ME, Moores KA, Clark RC, McFarlane AC, Strother SC, Bryant RA, Brown GC, Taylor JD 1243828800 Journal Article
System for computerized writing and drawing during fMRI Tam F, Churchill N, Strother SC, Graham SJ 1240027200 Presentation
Developing clinical fMRI for stroke patients Graham SJ, Strother SC 1237521600 Presentation
Evaluation and optimization of fMRI single-subject processing pipelines with NPAIRS and second-level CVA Magnetic Resonance Imaging Zhang J, Anderson JR, Liang LC, Pulapura SK, Gatewood L, Rottenberg DA, Strother SC 1233464400 Journal Article
Generative versus discriminate RBM models for classification of fMRI images NIPS 2008 Schmah T, Hinton G, Zemel R, Small SL, Strother SC 1228712400 Abstract
Pacific Rim collaborations: a Canadian perspective Brain Imaging and Behavior Grady C, Strother SC 1228107600 Journal Article
Optimizing the design and analysis of clinical functional magnetic resonance imaging research studies Biological Psychiatry Carter CS, Heckers S, Nichols T, Pine DS, Strother S 1226725200 Journal Article
Evaluation and comparison of GLM- and CVA-based fMRIprocessing pipelines with Java-based fMRI processing pipeline evaluation system Neuroimage Zhang J, Liang L, Anderson JR, Gatewood L, Rottenberg DA, Strother SC 1216094400 Journal Article
A java-based fMRI processing pipeline evaluation system for assessment of univariate general linear model and multivariate canonical variate analysis-based pipelines NeuroInformatics Zhang J, Liang L, Anderson JR, Gatewood L, Rottenberg DA, Strother SC 1210046400 Journal Article
Towards Shorter Scan Times Using Subject-Dependent Processing Pipelines for Clinical Tasks in fMRI ISMRM 16th Scientific Meeting and Exhibition Lee W, Mraz R, Tam F, Graham FJ, Strother SC 1209787200 Presentation
New horizons for the next era of human brain imaging, cognitive, and behavioral research: Pacific Rim interactivity Brain Imaging and Behavior Van Horn JD, Bandettini PA, Cheng K, Egan GF, Stenger VA, Strother S, Toga AW 1209182400 Journal Article
Multivariate Assessment of Preprocessing Choices as a Function of Age and Task Rotman Rounds Strother SC 1199163600 Presentation
Choosing Optimal Data Analysis Models in fMRI Studies: Interactions with Age and Task Intelligent Signal Processing Group Strother SC 1199163600 Presentation
Reproducibility across analysis streams IPAM: Mathematics in Brain Imaging Strother SC 1199163600 Presentation
Assessing fMRI Processing Choices as a Function of Age and Task MRI Group Monthly Rounds: Medical Biophysics Strother SC 1199163600 Presentation
Bayesian kernel methods for analysis of functional neuroimages IEEE Transactions on Medical Imaging Lukic AS, Wernick MN, Tzikas DG, Xu C, Likas A, Galatsanos NP, Yongyi Y, Fuqiang Z, Strother SC 1197867600 Journal Article
Effect of spatial alignment transformations in PCA and ICA of functional neuroimages IEEE Transactions on Medical Imaging Lukic AS, Wernick MN, Yongyi Yang, Kai Hansen L, Arfanakis K, Strother SC 1187323200 Journal Article
Image processing in fMRI Medical Biophysics summer-student lecture series Strother SC 1167627600 Presentation
Dysfunction of dorsolateral prefrontal cortex in antipsychotic-naïve schizophreniform psychosis. Psychiatry Research: Neuroimaging Harrison BJ, Yücel M, Shaw M, Brewer WJ, Nathan PJ, Strother SC, Olver JS, Egan GF, Velakoulis D, McGorry PD, Pantelis C 1164171600 Journal Article
Predictive Modeling in fMRI pipelines: Some uses and caveats Rotman Rounds Strother SC 1163998800 Presentation
Exploring predictive and reproducible modeling with the single-subject FIAC dataset Human Brain Mapping Chen X, Pereira F, Lee W, Strother SC, Mitchell T 1163566800 Journal Article
Kernel methods for functional neuroimaging analysis 2006 Fortieth Asilomar Conference on Signals, Systems and Computers Lukic AS, Wernick MN, Tzikas DG, Chen X, Likas A, Galatsanos NP, Yang Y, Zhao F, Strother SC 1162098000 Presentation
FMRI Image Processing & Data Analysis Choices: Do They Matter? SOCIETY FOR NEUROSCIENCE ABSTRACTS Strother SC 1160712000 Presentation
Mapping cerebral blood flow during speech production in hereditary ataxia Neuroimage Sidtis JJ, Gomez C, Naoum A, Strother SC, Rottenberg DA 1136091600 Journal Article
Evaluating brain activity in obsessive-compulsive disorder: Preliminary insights from a multivariate analysis Psychiatry Research: Neuroimaging Harrison BJ, Yucel M, Shaw M, Maruff P, Kyrios M, Brewer WJ, Strother SC, Nathan PJ, Scott AM, Pantelis C 1136091600 Journal Article
Motivation and synthesis of the FIAC experiment: Reproducibility of fMRI results across expert analyses Human Brain Mapping Poline JB, Strother SC, Dehaene-Lambertz G, Egan G, Lancaster J 1136091600 Journal Article
Dysfunction of dorsolateral prefrontal cortex in antipsychotic-naive schizophreniform psychosis Psychiatry Research: Neuroimaging Harrison BJ, Yucel M, Shaw M, Maruff P, Kyrios M, Brewer WJ, Strother SC, Nathan PJ, Scott AM, Pantelis C 1136091600 Journal Article
Evaluating fMRI preprocessing pipelines: Review of preprocessing steps for BOLD fMRI IEEE Engineering in Medicine and Biology Magazine Strother SC 1136091600 Journal Article
NIfTI-1: An example of linking informatics tools Linking Informatics of Neuroscience Communities Workshop Strother SC 1136091600 Presentation
Applications of Multivariate Analysis to Imaging in Drug Development Pfizer Global Clinical Technologies Group Strother SC 1136091600 Presentation
Managing and Optimising fMRI Pipelines Plenary lecture for functional Bioinformatics Resource Network (fBIRN) annual meeting Strother SC 1136091600 Presentation
Evaluating fMRI preprocessing pipelines. IEEE Engineering in Medicine and Biology Magazine Strother SC 1136091600 Journal Article
Support vector machines for temporal classification of block design fMRI data Neuroimage LaConte S, Strother SC, Cherkassky V, Anderson J, Hu X 1104555600 Journal Article
Functional connectivity during Stroop Task performance Neuroimage Harrison B, Shaw M, Yucel M, Purcell R, Brewer WJ, Strother SC, Egan GF, Olver JS, Nathan PJ, Pantelis C 1104555600 Journal Article
Age and Task Interactions with Choices in the fMRI Processing Pipeline Decoding Brain States with Machine Learning: Applications to fMRI Strother SC 1104555600 Presentation
Abnormal cingulo-prefrontal connectivity during Stroop task performance in first episode psychosis: A PET study INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY Harrison B, Brewer WJ, Shaw M, Yucel M, Strother SC, Nathan PJ, McGorry PD, Pantelis C 1086062400 Abstract
Reversible jump Markov chain Monte Carlo signal detection in functional neuroimaging analysis IEEE International Symposium on Biomedical Imaging Lukic AS, Wernick MN, Galatsanos NP, Yongyi Yang, Strother SC 1082001600 Journal Article
The effect of set on the resting state in functional imaging: A role for the striatum? Neuroimage Sidtis JJ, Strother SC, Rottenberg DA 1072933200 Journal Article
Optimizing the fMRI data-processing pipeline using prediction and reproducibility performance metrics. I. A preliminary group analysis Neuroimage Strother SC, LaConte S, Hansen LK, Anderson J, Zhang J, Pulapura S, Rottenberg D 1072933200 Journal Article
Impact of inter-subject image registration on group analysis of fMRI data International Congress Series Ardekani BA, Bachman AH, Strother SC, Fujibayashi Y, Yonekura Y 1072933200 Book Chapter
Data-Driven Discovery in Functional Neuroimaging RUMBA Seminar Series Strother SC 1072933200 Presentation
Dimensionality Reduction with RVMs and RJMCMC Computational Neuroscience UC Workshop Strother SC, Lukic A, Wernick M 1072933200 Presentation
Optimizing fMRI processing pipelines IPAM Graduate Summer School: Mathematics in Brain Imaging Strother SC 1072933200 Presentation
Optimizing fMRI Processing Pipelines: A Group Study Laboratory Visit to Seong-Gi Kim and William Eddy Strother SC 1072933200 Presentation
Predicting performance from functional imaging data: methods matter Neuroimage Sidtis JJ, Strother SC, Rottenberg DA 1064980800 Journal Article
Scale for auditory speech hallucinations (SASH), reliability SCHIZOPHRENIA RESEARCH Stephane M, Roberts S, Nasrallah HA, Strother SC, Adityanjee D, Schulz SC, Georgopoulos AP 1047704400 Abstract
The evaluation of preprocessing choices in single-subject BOLD fMRI using NPAIRS performance metrics Neuroimage LaConte S, Anderson J, Muley S, Frutiger S, Hansen LK, Yacoub E, Xiaoping H, Rottenberg D, Ashe J, Strother SC 1041397200 Journal Article
Evaluating subject specific preprocessing choices in multisubject fMRI data sets using data-driven performance metrics Neuroimage Shaw ME, Strother SC, Gavrilescu M, Podzebenko K, Waites A, Watson J, Anderson J, Jackson G, Egan G 1041397200 Journal Article
A developer's commentary on fiswidgets Neuroinformatics Strother SC 1041397200 Journal Article
How to Optimize a Multivariate Analysis of fMRI Data Sets: Linear Discriminants, Confusion Matrices and Reproducibility Metrics in the NPAIRS Resampling Framework fMRI Data Center Informatics Summer Workshop Strother SC 1041397200 Presentation
Data-driven discovery in functional neuroimaging Rotman Rounds Strother SC 1041397200 Presentation
Data-Driven Discovery in Functional Neuroimaging Data Processing Methods in Neuroscience Seminar Strother SC 1041397200 Presentation
Production and dosimetry of [14O]water for PET activation studies. Applied Radiation and Isotopes Sajjad M, Zaini MR, Liow JS, Rottenberg DA, Strother SC 1036126800 Journal Article
An ICA algorithm for analyzing multiple data sets International Conference on Image Processing Lukic AS, Wernick MN, Hansen LK, Strother SC 1032235200 Journal Article
A spatially robust ICA algorithm for multiple fMRI data sets IEEE International Symposium on Biomedical Imaging Lukic AS, Wernick MN, Hansen LK, Anderson J, Strother SC 1026014400 Journal Article
A reversible jump Markov chain Monte Carlo algorithm for analysis of functional neuroimages International Conference on Image Processing Lukic AS, Wernick MN, Galatsanos NP, Yongyi Yang, Strother SC 1024891200 Journal Article
Evaluation of an MRI-based partial volume correction for PET JOURNAL OF NUCLEAR MEDICINE Liow J, Zaini M, Rehm K, Strother SC, Anderson J, Schaper K, Rottenberg D 1024113600 Abstract
The quantitative evaluation of functional neuroimaging experiments: The NPAIRS data analysis framework Neuroimage Strother SC, Anderson J, Hansen LK, Kjems U, Kustra R, Siditis J, Frutiger S, Muley S, LaConte S, Rottenberg D 1009861200 Journal Article
Abnormal functional connectivity in post-traumatic stress disorder Neuroimage Shaw M, Strother SC, McFarlane AC, Morris P, Anderson J, Clark CR, Egan GF 1009861200 Journal Article
The quantitative evaluation of functional neuroimaging experiments:Mutual information learning curves Neuroimage Kjems U, Hansen LK, Anderson J, Frutiger SA, Sidtis JJ, Rottenberg D, Strother SC 1009861200 Journal Article
An evaluation of methods for detecting brain activations from functional neuroimages Artificial Intelligence in Medicine Lukic AS, Wernick MN, Strother SC 1009861200 Journal Article
Production and dosimetry of [O-14]water for PET activation studies Applied Radiation and Isotopes Sajjad M, Liow J-S, Zaini MR, Rottenberg DA, Strother SC 1009861200 Journal Article
Cluster analysis of activity time-series in motor learning Human Brain Mapping Balslev D, Nielsen FA, Frutiger SA, Sidtis JJ, Christiansen TB, Svarer C, Strother SC, Rottenberg DA, Hansen LK, Paulson OB, Law I 1009861200 Journal Article
A signal-detection approach for analysis of functional neuroimages IEEE Nuclear Science Symposium Conference Record Lukic AS, Wernick MN, Galatsanos NP, Yongyi Yang, Strother SC 1004850000 Journal Article
Evaluating preprocessing choices in single-subject BOLD-fMRI studies using data-driven performance metrics NEUROIMAGE LaConte S, Strother SC, Anderson J, Muley S, Frutiger S, Hansen LK, Yacob E, Hu XP, Rottenberg D 991368000 Abstract
"lyngby" a Matlab toolbox for fMRI analysis: Results of a user questionnaire NEUROIMAGE Hansen LK, Nielsen FA, Liptrot M, Strother SC, Lange N, Gade A, Rottenberg DA, Paulson OB 991368000 Abstract
Abnormal functional connectivity in post-traumatic stress disorder: insight from multivariate analysis NEUROIMAGE Shaw M, Strother SC, Anderson J, Egan GF, Clark R 991368000 Abstract
Effects of changes in experimental design on PET studies of isometric force Neuroimage Muley SA, Strother SC, Ashe J, Frutiger SA, Anderson JR, Sidtis JJ, Rottenberg DA 978325200 Journal Article
Generalizable singular value decomposition for ill-posed datasets Advances in Neural Information Processing Systems Kjems U, Hansen LK, Strother SC 978325200 Book Chapter
Consensus Inference in Neuroimaging Neuroimage Hansen LK, Nielsen FA, Strother SC, Lange N 978325200 Journal Article
Penalized discriminant analysis of [O-15]-water PET brain images with prediction error selection of smoothness and regularization hyperparameters IEEE Transactions on Medical Imaging Kustra R, Strother SC 978325200 Journal Article
Re-examining the correlation between H215O delivery and signal size: Towards shorter, more efficient PET sessions Physiological Imaging of the Brain with PET Morenu-Cantu JJ, Liow J-S, Sajjad M, Rottenberg DA, Strother SC 978325200 Book Chapter
Establishing behavioural correlates of functional imaging signals Physiological Imaging of the Brain with PET Sidtis JJ, Anderson JR, Strother SC, Rottenberg DA 978325200 Book Chapter
Multivariate predictive relationship between kinematic and functional activation patterns in a PET study of visuomotor learning Neuroimage Frutiger S, Strother SC, Anderson JR, Sidtis JJ, Arnold JB, Rottenberg DA 973054800 Journal Article
Fast PET scanning for brain activation studies with [O-14]water JOURNAL OF NUCLEAR MEDICINE Sajjad M, Liow JS, Zaini MR, Rottenberg DA, Strother SC 960004800 Abstract
Comparing reconstruction algorithms using a multi-variate analysis IEEE Transactions on Nuclear Science Liow JS, Anderson JR, Strother SC 959832000 Journal Article
Comparison of voxel- and volume-of-interest-based analyses in FDG PET scans of HIV positive and healthy individuals Journal of Nuclear Medicine Liow JS, Rehm K, Strother SC, Anderson JR, Morch N, Hansen LK, Schaper KA, Rottenberg DA 946702800 Journal Article
Arithmetic principles of two-dimensional and three-dimensional reconstructions Neurosurgery: The Scientific Basis of Clinical Practice Strother SC, Liow J-L 946702800 Book Chapter
On the independent components of functional neuroimages International Workshop on Independent Component Analysis and Blind Signal Separation Petersen KS, Hansen LK, Kolenda T, Rostrup E, Strother SC 946702800 Book Chapter
An evaluation of methods for detecting brain activations from PET or fMRI images IEEE Nuclear Science Symposium Lukic AS, Wernick MN, Strother SC 940737600 Journal Article
Establishing functional relationships between imaging data and speech production in cerebellar ataxia using perceptual ratings, acoustic analysis, and PET BRAIN AND LANGUAGE Sidtis JJ, Gomez C, Anderson JR, Strother SC, Rottenberg DA 940737600 Abstract
Comparison of matched BOLD and FAIR 4.0T-fMRI with [O-15]water PET brain volumes Medical Physics Zaini MR, Strother SC, Anderson JR, Liow J-S, Kjems U, Tegeler C, Kim S-G 926654400 Journal Article
Are brain functions really additive? Neuroimage Sidtis JJ, Strother SC, Anderson JR, Rottenberg DA 925531200 Journal Article
Enhancing the multivariate signal of [O-15] water PET studies with a new nonlinear neuroanatomical registration algorithm IEEE Transactions on Medical Imaging Kjems U, Strother SC, Anderson J, Law I, Hansen LK 924321600 Journal Article
Plurality and resemblance in fMRI data analysis Neuroimage Lange N, Strother SC, Anderson JR, Nielsen FA, Holmes A, Kolenda T, Savoy R, Hansen LK 915166800 Journal Article
Generalizable patterns in neuroimaging: How many principal components? Neuroimage Hansen LK, Larsen J, Nielsen FA, Strother SC, Rostrup E, Savoy R, Lange N, Sidtis J, Svarer C, Paulson OB 915166800 Journal Article
Reproducibility of BOLD-based functional MRI obtained at 4T Human Brain Mapping Tegeler C, Strother SC, Anderson JR, Kim S-G 915166800 Journal Article
Establishing functional relationships between data and speech production in cerebellar ataxia using perceptual ratings, acoustic signals, and PET Brain and Language Sidtis JJ, Gomez C, Anderson JR, Strother SC, Rottenberg DA 915166800 Journal Article
A symbolic environment for visualizing activated foci in functional neuroimaging datasets Medical Image Analysis Rehm K, Lakshminaryan K, Frutiger S, Schaper KA, Sumners DW, Strother SC, Anderson JR, Rottenberg DA 883630800 Journal Article
On the detection of activation patterns using principal components analysis Quantitative Functional Brain Imaging with Positron Emission Tomography Ardekani BA, Strother SC, Anderson JR, Law I, Paulson OB, Kanno I, Rottenberg DA 883630800 Book Chapter
Measuring activation pattern reproducibility using resampling techniques Quantitative Functional Brain Imaging with Positron Emission Tomography Strother SC, Rehm K, Lange N, Anderson JR, Schaper KA, Hansen LK, Rottenberg DA 883630800 Book Chapter
Predicting speech rate in normal and ataxic speakers from functional imaging data Brain and Language Sidtis JJ, Gomez C, Anderson JR, Strother SC, Rottenberg DA 883630800 Journal Article
The effect of image smoothing on a disease specific pattern of cerebral atrophy for HIV seropositive subjects in PET FDG studies. JOURNAL OF NUCLEAR MEDICINE Liow JS, Strother SC, Anderson JR, Rehm K, Schaper KA, Rottenberg DA 865137600 Abstract
Activation pattern reproducibility: Measuring the effects of group size and data analysis models Human Brain Mapping Strother SC, Lange N, Anderson JR, Schaper KA, Rehm K, Hansen LK, Rottenberg DA 852094800 Journal Article
Improved resolution for PET volume imaging through three-dimensional iterative reconstruction Journal of Nuclear Medicine Liow J-S, Strother SC, Rehm K, Rottenberg DA 852094800 Journal Article
Nonlinear versus linear models in functional neuroimaging: Learning curves and generalization crossover Lecture Notes in Computer Science Morch N, Hansen LK, Strother SC, Svarer C, Rottenberg DA, Lautrup B, Savoy R, Paulson OB 852094800 Journal Article
Quantification of dynamic FDOPA scans for 3D PET without scatter correction JOURNAL OF NUCLEAR MEDICINE Liow JS, Strother SC, Rottenberg DA 833774400 Abstract
Signal and noise tradeoffs with scatter correction for 3D PET [O-15]water brain activation studies JOURNAL OF NUCLEAR MEDICINE Liow JS, Rehm K, Anderson JR, Strother SC, Rottenberg DA 833774400 Abstract
Abnormal cerebral glucose metabolism in HIV-1 seropositive subjects with and without dementia Journal of Nuclear Medicine Rottenberg DA, Sidtis JJ, Strother SC, Schaper KA, Anderson JR, Nelson MJ, Price RW 820472400 Journal Article
[15O]water PET: More 'noise' than Signal? Quantification of Brain Function using PET Strother SC, Sidtis JJ, Anderson JR, Schaper K, Rottenberg DA 820472400 Book Chapter
Data Processing Summary Quantification of Brain Function using PET Strother SC 820472400 Book Chapter
Linear models of orthogonal subspaces and networks from functional activation pet studies of the human brain INFORMATION PROCESSING IN MEDICAL IMAGING COMPUTATIONAL IMAGING AND VISION Strother SC, Anderson JR, Schaper KA, Sidtis JS, Rottenberg DA 801979200 Presentation
Commentary and opinion .1. Principal component analysis, variance partitioning, and functional connectivity Journal of Cerebral Blood Flow & Metabolism Strother SC, Kanno I, Rottenberg DA 799300800 Journal Article
Principal component analysis, variance partitioning and "functional connectivity" Journal of Cerebral Blood Flow & Metabolism Strother SC, Kanno I, Rottenberg DA 788936400 Journal Article
Principal component analysis and the scaled subprofile model compared to intersubject averaging and statistical parametric mapping .1. Functional connectivity of the human motor system studied with [O-15]water PET Journal of Cerebral Blood Flow & Metabolism Strother SC, Anderson JR, Schaper KA, Sidtis JS, Liow J-S, Woods RP, Rottenberg DA 788936400 Journal Article
Linear models of orthogonal subspaces and activated networks from functional activation PET studies of the human brain Computational Imaging and Vision Strother SC, Anderson JR, Schaper KA, Sidtis JS, Rottenberg DA 788936400 Book Chapter
Visualization of neural networks using saliency maps IEEE International Conference on Neural Networks Morch N, Kjems U, Hansen LK, Svarer C, Law I, Lautrup B, Strother SC, Rehm K 788936400 Journal Article
Massive weight sharing: A cure for extremely ill-posed problems Proceedings of the workshop on supercomputing in brain research: From tomography to neural networks Lautrup B, Hansen LK, Law I, Moerch N, Svarer C, Strother SC 788936400 Book Chapter
Improved resolution via 3D iterative reconstruction for PET volume imaging IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference Liow J-S, Strother SC, Rottenberg DA 783493200 Journal Article
Improved Resolution via 3D Iterative Reconstruction for PET Volume Imaging JOURNAL OF NUCLEAR MEDICINE Liow JS, Strother SC 770788800 Abstract
Noise and signal decoupling in maximum likelihood reconstructions and Metz filters for PET brain images Physics in Medicine and Biology Liow J-S, Strother SC 757400400 Journal Article
Display of merged multimodality brain images using interleaved pixels with independent color scales Journal of Nuclear Medicine Rehm K, Strother SC, Anderson JR, Schaper KA, Rottenberg DA 757400400 Journal Article
Quantitative comparisons of image registration techniques based on high resolution MRI of the brain Journal of Computer Assisted Tomography Strother SC, Anderson JR, Xu X-L, Liow J-S, Bonar DC, Rottenberg DA 757400400 Journal Article
Error-bounds for 5 image registration techniques based on high-resolution MRI QUANTIFICATION OF BRAIN FUNCTION - TRACER KINETICS AND IMAGE ANALYSIS IN BRAIN PET INTERNATIONAL CONGRESS SERIES Anderson JR, Strother SC, Xu XL, Bonar DC, Rottenberg DA 754722000 Presentation
Iterative algebraic reconstruction algorithms for emission computed tomography: A unified framework and its application to positron emission tomography Medical Physics Xu X-L, Liow J-S, Strother SC 752130000 Journal Article
Error-bounds for 5 registration techniques based on high-resolution MRI of the brain JOURNAL OF NUCLEAR MEDICINE Anderson JR, Strother SC, Xu XL, Bonar DC, Rottenberg DA 739512000 Abstract
Effect of Smear-Correcting Radial Arterial Blood Activity Curves on FDG-PET Measurements of Cerebral Metabolic-Rate for Glucose JOURNAL OF NUCLEAR MEDICINE Palmer BM, Strother SC, Rottenberg DA 739512000 Abstract
The convergence of object dependent resolution in maximum likelihood based tomographic image reconstruction Physics in Medicine and Biology Liow J-S, Strother SC 725864400 Journal Article
Graphical analysis of MR feature space for measurement of CSF, gray-matter and white-matter volumes Journal of Computer Assisted Tomography Bonar DC, Schaper KA, Anderson JR, Rottenberg DA, Strother SC 725864400 Journal Article
Effect of delay and dispersion correction of arterial blood activity curves on FDG-PET measurements of cerebral metabolic rates for glucose Quantification of Brain Function: Tracer Kinetics and Image Analysis in Brain PET Palmer BM, Strother SC, Rottenberg DA 725864400 Book Chapter
Error bounds for five registration techniques based on high resolution MRI Quantification of Brain Function: Tracer Kinetics and Image Analysis in Brain PET Anderson JR, Strother SC, Xiaoliang X, Bonar DC, Rottenberg DA 725864400 Book Chapter
Using principal component analysis to identify a disease independent pattern of cerebral metabolic activation: The reticular activating system? Quantification of Brain Function: Tracer Kinetics and Image Analysis in Brain PET Strother SC, Moeller JR, Sidtis JJ, Rottenberg DA 725864400 Book Chapter
A novel iterative reconstruction algorithm for emission computed tomography IEEE International Conference on Acoustics, Speech, and Signal Processing Xu XL, Liow J-S, Strother SC 725864400 Journal Article
EFFECT OF DELAY AND DISPERSION CORRECTION OF ARTERIAL BLOOD ACTIVITY CURVES ON FDG-PET MEASUREMENTS OF CEREBRAL METABOLIC-RATE FOR GLUCOSE QUANTIFICATION OF BRAIN FUNCTION - TRACER KINETICS AND IMAGE ANALYSIS IN BRAIN PET INTERNATIONAL CONGRESS SERIES PALMER BM, STROTHER SC, ROTTENBERG DA 723186000 Presentation
Performance of maximum likelihood based image reconstruction for quantitative imaging IEEE Nuclear Science Symposium and Medical Imaging Conference Liow J-S, Strother SC 694242000 Journal Article
A non-iterative linear algebraic algorithm for image reconstruction IEEE Nuclear Science Symposium and Medical Imaging Conference Xu X-L, Liow J-S, Strother SC 694242000 Journal Article
Noise and signal decoupling in maximum likelihood reconstructions and Metz filters for PET images IEEE Nuclear Science Symposium and Medical Imaging Conference Liow J-S, Strother SC 694242000 Journal Article
Practical tradeoffs between noise, quantitation, and number of iterations for maximum likelihood-based reconstructions IEEE Transactions on Medical Imaging Liow J-S, Strother SC 691563600 Journal Article
The metabolic landscape of cortico-basal ganglionic degeneration: regional asymmetries studied with positron emission tomography Journal of Neurology, Neurosurgery & Psychiatry Eidelberg D, Dhawan V, Moeller JR, Sidtis JJ, Ginos JZ, Strother SC, Cedarbaum J, Greene P, Fahn S, Powers JM, Rottenberg DA 686289600 Journal Article
A linear spatial correlation model, with applications to Positron Emission Tomography Journal of the American Statistical Association Worsley KJ, Evans AC, Strother SC, Tyler JL 662706000 Journal Article
Effects of percent thresholding on the extraction of (18F)fluorodeoxyglucose positron emission tomographic region-of-interest data Journal of Cerebral Blood Flow & Metabolism Rottenberg DA, Moeller JR, Strother SC, Sidtis JJ, Dhawan V 662706000 Journal Article
Abnormal cerebral glucose metabolism in long-term survivors of childhood acute lymphocytic leukemia Annals of Neurology Phillips PC, Moeller JR, Sidtis JJ, Dhawan V, Steinherz PG, Strother SC, Ginos JZ, Rottenberg DA 662706000 Journal Article
Absolute quantitation in neurological PET: Do we need it? Journal of Cerebral Blood Flow & Metabolism Strother SC, Liow J-S, Moeller JR, Sidtis JJ, Dhawan V, Rottenberg DA 662706000 Journal Article
A regional covariance approach to the analysis of functional patterns in positron emission tomographic data Journal of Cerebral Blood Flow & Metabolism Moeller JR, Strother SC 662706000 Journal Article
Performance of maximum likelihood based iterative image reconstruction for quantitative imaging IEEE Engineering in Medicine and Biology Society Strother SC, Liow J-S 662706000 Book Chapter
Measuring PET scanner sensitivity - relating countrates to image signal-to-noise ratios using noise equivalent counts IEEE Transactions on Nuclear Science Strother SC, Casey ME, Hoffman EJ 640324800 Journal Article
The metabolic anatomy of Parkinson's disease: Complementary [F-18]Fluorodeoxyglucose and [F-18]Fluorodopa positron emission tomographic studies Movement Disorders Eidelberg D, Moeller JR, Dhawan V, Sidtis JJ, Ginos JZ, Strother SC, Cedarbaum J, Greene P, Fahn S, Rottenberg DA 631170000 Journal Article
Practical tradeoffs between noise, resolution and quantitation, and number of iterations for maximum likelihood reconstructions IEEE Nuclear Science Symposium Liow J-S, Strother SC 631170000 Journal Article
In defense of quantitative PET techniques Journal of Nuclear Medicine Rottenberg DA, Strother SC, Moeller JR 607410000 Journal Article
Positron emission tomographic measurement of blood-to-brain and blood-to-tumor transport of Rb-82 . 2. Clinical-data and validation of technique Physics in Medicine and Biology Dhawan V, Jarden JO, Moeller JR, Strother SC, Rottenberg DA 599634000 Journal Article
The time course of steroid action on blood-to-brain and blood-to-tumor transport of [Rb-82]: a positron emission tomographic study Annals of Neurology Jarden JO, Dhawan V, Moeller JR, Strother SC, Rottenberg DA 599634000 Journal Article
Effect of selecting a fixed dephosphorylation rate on the estimation of rate constants and rCMRGlu from dynamic [F-18] fluorodeoxyglucose PET data Journal of Nuclear Medicine Dhawan V, Moeller JR, Strother SC, Evans AC, Rottenberg DA 599634000 Journal Article
Positron emission tomographic measurement of blood-to-brain and blood-to-tumor transport of RB-82 .1. Error analysis and computer-simulations Physics in Medicine and Biology Dhawan V, Poltorak A, Moeller JR, Jarden JO, Strother SC, Thaler H, Rottenberg DA 599634000 Journal Article
Effect of blood curve smearing on the accuracy of parameter estimates obtained for [Rb-82]/PET studies of blood-brain barrier permeability Physics in Medicine and Biology Dhawan V, Jarden JO, Strother SC, Rottenberg DA 568011600 Journal Article
Stability of regional cerebral glucose metabolism in the normal brain measured by positron emission tomography Journal of Nuclear Medicine Tyler JL, Strother SC, Zatorre RJ, Alivisatos B, Worsley KJ, Diskic M, Yamamoto YL 568011600 Journal Article
The metabolic anatomy of paraneoplastic cerebellar degeneration Annals of Neurology Anderson NE, Posner JB, Sidtis JJ, Moeller JR, Strother SC, Dhawan V, Rottenberg DA 568011600 Journal Article
The metabolic pathology of the AIDS dementia complex Annals of Neurology Rottenberg DA, Moeller JR, Strother SC, Sidtis JJ, Navia BA, Dhawan V, Ginos JZ, Price PW 536475600 Journal Article
Differences in cerebral blood flow and glucose utilization in vegetative versus locked-in patients Annals of Neurology Levy DE, Sidtis JJ, Rottenberg DA, Jarden JO, Strother SC, Dhawan V, Ginos JZ, Tramo MJ, Evans AC, Plum F 536475600 Journal Article
Scaled subprofile model: a statistical approach to the analysis of functional patterns in positron emission tomographic data Journal of Cerebral Blood Flow & Metabolism Moeller JR, Strother SC, Sidtis JJ, Rottenberg DA 536475600 Journal Article
Headholders for functional brain imaging Journal of Cerebral Blood Flow & Metabolism Strother SC, Perlmutter JS 536475600 Journal Article
[N-13] cisplatin PET to assess pharmacokinetics of intra-arterial versus intravenous chemotherapy for malignant brain tumors Journal of Nuclear Medicine Ginos JZ, Cooper AJL, Dhawan V, Lai JC, Strother SC, Alcock N, Rottenberg DA 536475600 Journal Article
Reduced cerebral glucose metabolism and increased brain capillary permeability following high-dose methotrexate chemotherapy: a positron emission tomographic study Annals of Neurology Phillips PC, Dhawan V, Strother SC, Sidtis JJ, Evans AC, Allen JC, Rottenberg DA 536475600 Journal Article
A technique to reject scattered radiation in PET transmission scans International Workshop on Physics and Engineering of Computerized Multidimensional Imaging and Processing Thompson CJ, Dagher A, Lunney DN, Strother SC, Evans AC 504939600 Book Chapter
Correcting positron emission tomography data for cerebral atrophy Journal of Cerebral Blood Flow & Metabolism Strother SC, Rottenberg DA 504939600 Journal Article
Sensitivity of positron detection for a pair of opposed detectors compared with ring scanners using image-reconstruction Journal of Nuclear Medicine Strother SC, Allard C 504939600 Journal Article
An inter-center comparison of region of interest and resolution effects for normal 18F-fluorodeoxyglucose studies with PET Journal of Cerebral Blood Flow & Metabolism Strother SC, Tyler JK, Peters T, Thompson C, Evans AC, Diksic M, Meyer E, Yamamoto YL, Feindel W 473403600 Journal Article
An improved approach for measurement of regional cerebral rate constants in the deoxyglucose method with positron emission tomography Journal of Cerebral Blood Flow & Metabolism Kato A, Diksic M, Yamamoto YL, Strother SC, Feindel W 470725200 Journal Article
A contrast-detail-noise approach to the study of display conditions IEEE Computer Society Strother SC, Peters TM 410245200 Journal Article
Application of spatial filtering to CT imagery IEEE Computer Society Peters TM, Strother SC 383806800 Journal Article
Analysing dose limited radiation imaging systems New Zealand Medical Physics and Biomedical Engineering Journal Peters TM, Strother SC 347173200 Journal Article
The Delta 2020 CT Scanner New Zealand Medical Physics and Biomedical Engineering Journal Strother SC 252478800 Journal Article
Stability and Reproducibility in fMRI Analysis Optimization for Machine Learning Strother SC, Rasmussen PM, Churchill NW, Hansen LK -28800 Book Chapter
Early cerebral small vessel disease and brain volume, cognition, and gait. Ann Neurol. Smith EE, O’Donnell, M, Dagenais G, Lear SA, Wielgosz A, Sharma M, Poirier P, Stotts G, Black S, Strother SC, Noseworthy MD, Modi J, Goyal M, Batool, S, Sanchez K, Hill V, McCreary C, Frayne R, Shofiqul I, DeJesus J, Sumathy R, Teo K, Yusuf S -28800 Journal Article

Education

  • 1976: B.Sc., Physics & Mathematics, Auckland University Auckland, New Zealand
  • 1979: M.Sc., Hons., Physics, Auckland University Auckland, New Zealand
  • 1986: Ph.D., Electrical Engineering, McGill University Montreal, Canada

Academic Appointments

Reviewership

Committee

Editorial Board

  • 2003–Present: Human Brain Mapping, Associate Editor
  • 2007–Present: Frontiers in NeuroInformatics, Review Editor
  • 2013–Present: Frontiers in Neuroscience: Brain Imaging Models, Associate Editor

Research Projects

External

  • 2005–2007: fMRI Research via Database Mining, Management. Project 2: Optimizing fMRI Processing Pipelines URL
    Collaborators: MS Gazzaniga, PhD, Dartmouth College

    Sponsors: National Institute of Mental Health, NIH, 1,500,000 (USD)

    Research Grant
    Core-Project 1: J Van Horn; Project 2: SC Strother; Project 3: M D'Esposito Project 2: US$200,000
  • 2005–2008: Network mechanisms underlying cognition and recovery of function in the human brain URL
    Collaborators: AR McIntosh

    Sponsors: Bridging Brain, Mind, and Behaviour, James S. McDonnell Foundation, 4,200,000 (USD)

    Research Grant
    Link: http://www.jsmf.org/
  • 2007–2010: Memory and attention in people who experienced a single life-threatening event
    Collaborators: Levine, B., Anderson, A.K., McKinnon, M., Moscovitch, M., Feinstein, A., Mayberg, H., Graham, S.I., Strother, S., and McIntosh, A.R.

    Sponsors: National Institute of Mental Health, NIH, 731,652 (USD)

    Research Grant
    R01 MH076067-02,(3 years) US$10,944 (Equipment).
  • 2007–2011: Towards Clinical FMRI: Characterizing a Rapid, Multitask, fMRI Battery as a Function of Age
    Collaborators: S Graham, C Grady, J Ween

    Sponsors: CIHR, 240,000 (CAD)

    Research Grant
  • 2008–2011: Detection of Drug Effect in Small Groups using PET
    Collaborators: A. Lukic

    Sponsors: National Institute of Mental Health, 750,000

    Research Grant
  • 2010–2013: Network mechanisms underlying cognition and recovery of function in the human brain URL
    Collaborators: AR McIntosh

    Sponsors: Bridging Brain, Mind, and Behavior, James S. McDonnell Foundation, 6,000,000 (USD)

    Research Grant
    Link: http://www.jsmf.org/
  • 2010–2013: 800-Person Population Urban-Rural Epidemiological MRI-SubStudy
    Collaborators: E. Smith

    Sponsors: Canadian Stroke Network and Heart and Stroke Foundation, 600,000

    Research Grant
  • 2010–2015: Optimizing signal detection in functional neuroimaging using resampled performance metrics

    Sponsors: NSERC, 138,000

    Research Grant
  • 2011–2012: Tablet Technology for Assessing Dementia
    Collaborators: Simon Graham

    Sponsors: CIHR, 116,000

    Research Grant
  • 2011–2013: Network mechanisms underlying cognition and recovery of function in the human brain
    Collaborators: AR McIntosh

    Sponsors: Ontario Brain Institute, 6,000,000

    Research Grant
  • 2012: Early and Specific Dementia Diagnosis Using Imaging and Pattern Classification Software
    Collaborators: D. Matthews

    Sponsors: SBIR, 150,000 (USD)

    Research Grant
    Phase 1
  • 2012–2014: Optimising Variability in fMRI Measurements as A Function of Age

    Sponsors: CIHR, 100,000

    Research Grant
  • 2013–2014: 'NeuroCare' as an Innovation in Intervention: A Neurophysiological Approach to Determine Readiness for Return to Activity
    Collaborators: M. Kiethly

    Sponsors: CIHR, 92,000

    Research Grant
  • 2013–2014: Neurodegenerative Disease in Former Athletes with Traumatic Brain Injury
    Collaborators: B. Levine

    Sponsors: CIHR, 100,000

    Research Grant
  • 2013–2015: Early and Specific Dementia Diagnosis Using Imaging and Pattern Classification Software
    Collaborators: D. Matthews

    Sponsors: SBIR, 500,000 (USD)

    Research Grant
    Phase 2
  • 2013–2015: Integrated Data Organising Centre: BrainCODE URL
    Collaborators: Ken Evans

    Sponsors: Ontario Brain Institute, 2,100,000

  • 2013–2015: High-throughput behavioral platform to advance neurodegenerative disease drug discovery
    Collaborators: M. Pardo, Western University

    Sponsors: W. Garfield Weston Foundation, 1,250,000 (CAD)

    Research Grant
  • 2013–2016: Validation of ocular measures as potential biomarkers for early detection of brain amyloid and neurodegeneration
    Collaborators: Sandra Black

    Sponsors: Brain Canada (MIRI), 1,500,000

  • 2013–2018: The Physiological Basis of Resting State fMRI
    Collaborators: Jean Chen

    Sponsors: CIHR, 550,000

  • 2013–2018: The Role of Ischemic Vasculopathy in Adult Onset Neurodegenerative Diseases
    Collaborators: M. Strong

    Sponsors: Ontario Brain Institute, 28,500,000

  • 2013–2018: PURE-MIND: A Population-based Study of Covert Cerebrovascular Disease and Its Contribution to Age-Related Cognitive Decline
    Collaborators: E. Smith

    Sponsors: CIHR, 1,200,000

  • 2013–2018: "NeuroCare" as Innovation in Intervention: A Neurophysiological Approach to Determine Readiness for Return to Activity.
    Collaborators: M. Keithly

    Sponsors: CIHR and Ontario Brain Institute, 1,066,000

  • 2014–2015: A system for automatic lesion delineation, with application to prediction of recovery from stroke and treatment efficacy

    Sponsors: Canadian Partnership for Stroke Recovery, 50,000

  • 2014–2017: CBRAIN: Canadian Brain Research And Informatics Platform
    Collaborators: Alan Evans

    Sponsors: Brain Canada, 1,999,000

  • 2014–2019: Optimising fMRI Detection of Longitudinal Changes in Age-Related Brain Disorders

    Sponsors: CIHR, 586,000

Curriculum Vitae

Contact

The Rotman Research Institute
Baycrest
3560 Bathurst Street, 1058
Toronto, Ontario,
Canada M6A 2E1 Phone: 416 785 2500 x2956 Email: sstrother@research.baycrest.org Fax: 416 785 2862