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Reference (APA Format)

Palmer B.M., Strother S.C. & Rottenberg D.A. 1993. Effect of delay and dispersion correction of arterial blood activity curves on FDG-PET measurements of cerebral metabolic rates for glucose. In (Eds. Uemura K., Lassen N.A., Jones T. & Kanno I.), Quantification of Brain Function: Tracer Kinetics and Image Analysis in Brain PET (pp. 153-160). Amsterdam, The Netherlands: Elsevier Science Publishers B.V..

Book Title

Quantification of Brain Function: Tracer Kinetics and Image Analysis in Brain PET

Chapter Title

Effect of delay and dispersion correction of arterial blood activity curves on FDG-PET measurements of cerebral metabolic rates for glucose

Editor(s)

Uemura K., Lassen N.A., Jones T. & Kanno I.

Publisher

Elsevier Science Publishers B.V.

City

Amsterdam, The Netherlands

Opening Paragraph

Quantitative measurements of regional cerebral metabolic rate for glucose (rCMR,,,) with FDG-PET require the acquisition of a tissue arterial blood activity curve (BAC), which is usually measured by radial arterial sampling. Although arterial sampling permits excellent quantitation of radioactivity, temporal smearing errors are unavoidable due to differences in the tracer's transit time and dispersion from the left ventricle to the carotid and radial arteries. In addition to this internal smearing, discrete arterial blood samples are usually taken with an automatic blood sampling system, which introduces significant external smearing into the measured radial arterial BAC [I].

Volume

1030

Year

1993

Pages

153-160

Authors

Palmer B.M., Strother S.C. & Rottenberg D.A.