Research | Baycrest

Addis, Donna Rose Dr.

Donna Rose Addis

Dr. Donna Rose Addis

Canada 150 Research Chair In Cognitive Neuroscience of Memory and Aging

Senior Scientist Rotman Research Institute

Research Focus

Humans have an amazing capacity to mentally traverse time and space: we can remember ourselves in the past and imagine ourselves in the future. My research program combines neuroimaging, behavioural and neuropsychological methods to investigate how the human brain enables us to remember past experiences, imagine future events and construct a coherent sense of self. In particular, I have focused on the qualities of memories and imagined events, the types of details that comprise these mental representations and the processes that underlie their (re)construction. I have also examined how these abilities change in healthy aging, psychiatric disorders, such as depression, as well as in the context of brain damage in dementia and epilepsy. My research in this area led to the development of our Constructive Episodic Simulation Hypothesis, a theory that describes the overlapping cognitive processes involved in memory and imagination. Moreover, my work has elucidated the role of specific brain regions (e.g., the hippocampus) and whole-brain networks in memory and imagination, as well as other forms of creative cognition.

Publications

Title Source (Journal/Book/Conference) Authors/Presenters Published On Type
Consequences of hippocampal damage across the autobiographical memory network in left temporal lobe epilepsy Brain Addis DR, Moscovitch M, McAndrews MP 1188619200 Journal Article
Changes in Autobiographical Memory Retrieval Network Following Removal of Functionally Active Regions in the Medial Temporal Lobe Cognitive Neuroscience Society McAndrews MP, Addis DR, Moscovitch M, Shah M 1167627600 Presentation
Hippocampal atrophy and autobiographical memory in temporal lobe epilepsy: Preliminary findings Meeting of the International Neuropsychological Society Addis DR, Moscovitch M, Black S, Gao FQ, McAndrews MP 1138770000 Presentation
How do retrieval networks change following removal of functionally active regions in the temporal lobe Annual Meeting of Memory Disorders Research Society: Epilepsy and Memory - New Insights into Process and Structure Addis DR, Moscovitch M, McAndrews MP 1136091600 Presentation
Unilateral temporal lobe epilepsy and changes in the engagement and connectivity of the autobiographical memory retrieval network International Conference on Memory Addis DR, Moscovitch M, McAndrews MP 1136091600 Presentation
Alterations in the autobiographical retrieval network associated with left medial temporal dysfunction Organization for Human Brain Mapping McAndrews MP, Addis DR, Moscovitch M 1136091600 Presentation
Functional neuroanatomy of remote episodic, semantic and spatial memory: a unified account based on multiple trace theory Journal of Anatomy Moscovitch M, Rosenbaum RS, Gilboa A, Addis DR, Westmacott R, Grady C, McAndrews MP, Levine B, Black SE, Winocur G, Nadel L 1120449600 Journal Article
Hippocampal complex contribution to retention and retrieval of recent and remote episodic and semantic memories: evidence from behavioral and neuroimaging studies of healthy and brain-damaged people Dynamic Cognitive Processes Moscovitch M, Westmacott R, Gilboa A, Addis DR, Rosenbaum RS, Viskontas I, Priselac S, Svoboda E, Ziegler M, Black SE, Gao F, Grady CL, Freedman M, Köhler S, Leach L, Levine B, McAndrews MP, Nadel L, Proulx G, Richards B, Ryan L, Stokes K, Winocur G 1104555600 Book Chapter
Neural substrates of autobiographical memory retrieval in unilateral temporal lobe epilepsy: an fMRI study Organization for Human Brain Mapping Addis DR, Moscovitch M, Crawley AP, McAndrews MP 1104555600 Presentation
Recollective qualities modulate hippocampal activation during autobiographical memory retrieval Hippocampus Addis DR, Moscovitch M, Crawley AP, McAndrews MP 1072933200 Journal Article
Characterizing spatial and temporal features of autobiographical memory retrieval networks: a partial least squares approach NeuroImage Addis DR, McIntosh AR, Moscovitch M, Crawley AP, McAndrews MP 1072933200 Journal Article
Qualities of autobiographical memory modulate hippocampal activation during retrieval: preliminary findings of an fMRI study BRAIN AND COGNITION Addis DR, Moscovitch M, Crawley AP, McAndrews MP 1072933200 Abstract
An fMRI study of brain areas active during recall of personal experiences. University Health Network Addis DR, Moscovitch M, Crawley AP, McAndrews MP 1072933200 Presentation
Recollective qualities modulate hippocampal activation during autobiographical memory retrieval Cognitive Neuroscience Society Addis DR, Moscovitch M, Crawley AP, McAndrews MP 1041397200 Presentation

Academic Appointments

  • 2018–Present: Canada 150 Research Chair In Cognitive Neuroscience of Memory and Aging
  • 2018–Present: Senior Scientist, Rotman Research Institute
  • 2018–Present: Honorary Professor, School of Psychology, The University of Auckland

Contact

The Rotman Research Institute
Baycrest
3560 Bathurst Street, 702
Toronto, Ontario
Canada M6A 2E1 Phone: (416) 785-2500 x6480 Email: draddis@research.baycrest.org Fax: (416) 785-2862